DMT1 blocker 2, Compound 12f, is a direct inhibitor of divalent metal transporter 1 (DMT1) with an IC50 of 0.83 μM, is expected to block iron uptake by enterocytes in vivo.
DMT1 blocker 2, Compound 12f, is a direct inhibitor of divalent metal transporter 1 (DMT1) with an IC50 of 0.83 μM, is expected to block iron uptake by enterocytes in vivo.
Cell Research
Cell Line
Type
Value
Description
References
Product Information
Catalog Num
A18999
Formula
C16H13N3O
Molecular Weight
263.29
CAS Number
1062648-63-8
SMILES
OC1=C2C3=C(C=CC=C3)CCC2=NN1C4=NC=CC=C4
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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