SEC inhibitor KL-2
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | SEC inhibitor KL-2 (KL-2), a peptidomimetic lead compound, is a potent, selective super elongation complex (SEC) inhibitor and disrupts the interaction between the SEC scaffolding protein AFF4 and P-TEFb, resulting in impaired release of Pol II from promoter-proximal pause sites and a reduced average rate of processive transcription elongation. |
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Catalog Num | A19043 |
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Formula | C17H13ClFNO3 |
Molecular Weight | 333.74 |
CAS Number | 900308-51-2 |
SMILES | O=C(NC1=CC(Cl)=CC=C1C)/C(O)=C/C(C2=CC=C(F)C=C2)=O |
Synonyms | KL-2 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2