MK-8719

Catalog No.: A18839

OGA inhibitor

MK-8719

MK-8719 Chemical Structure

CAS NO. 1382799-40-7

MK-8719 is a highly potent and selective OGA inhibitor (EC50 = 52.7 nM) which is a Potential Treatment for Tauopathies. MK-8719 showed excellent CNS penetration that has been advanced to first-in-human phase I clinical trials.

Availability: In stock

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5 mg
$350.00
10 mg
$650.00
50 mg
$2,000.00
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Biological Activity

MK-8719 is a highly potent and selective OGA inhibitor (EC50 = 52.7 nM) which is a Potential Treatment for Tauopathies. MK-8719 showed excellent CNS penetration that has been advanced to first-in-human phase I clinical trials.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 37.28 mL 186.38 mL 372.76 mL
0.5 mM 7.46 mL 37.28 mL 74.55 mL
1 mM 3.73 mL 18.64 mL 37.28 mL
5 mM 0.75 mL 3.73 mL 7.46 mL

*The above data is based on the productmolecular weight 268.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18839
Actions Inhibitor
M. Wt 268.27
Formula C9H14F2N2O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1382799-40-7
Synonyms MK-8719; MK 8719; MK8719;
SMILES O[[email protected]]1[[email protected]](O)[[email protected]@]2([H])N=C(NCC)S[[email protected]@]2([H])O[[email protected]@H]1C(F)F

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