MK-8719
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | MK-8719 is a highly potent and selective OGA inhibitor (EC50 = 52.7 nM) which is a Potential Treatment for Tauopathies. MK-8719 showed excellent CNS penetration that has been advanced to first-in-human phase I clinical trials. |
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Catalog Num | A18839 |
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Formula | C9H14F2N2O3S |
Molecular Weight | 268.27 |
CAS Number | 1382799-40-7 |
SMILES | O[C@H]1[C@H](O)[C@@]2([H])N=C(NCC)S[C@@]2([H])O[C@@H]1C(F)F |
Synonyms | MK-8719; MK 8719; MK8719; |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 52 mg/mL (193.83 mM) | |
Water | 52 mg/mL (193.83 mM) | ||
Ethanol | 52 mg/mL (193.83 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 37.28 mL | 186.38 mL | 372.76 mL |
0.5 mM | 7.46 mL | 37.28 mL | 74.55 mL |
1 mM | 3.73 mL | 18.64 mL | 37.28 mL |
5 mM | 0.75 mL | 3.73 mL | 7.46 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2