Biochanin A (4-Methylgenistein)

Catalog No.: A10146

Biochanin A (4-Methylgenistein) Chemical Structure

CAS NO. 491-80-5

Biochanin A is an antiproliferative and anti-inflammatory agent that inhibits iNOS expression and lipopolysacharide (LPS)-induced nitric oxide production in macrophages. Additionally, Biochanin A displays the ability to block phosphorylation of IκBα and p38 MAPK, which prevents NF-κB activation. Furthermore, Biochanin A has been observed to suppress IL-6, IL-1β, and TNF-α production.

Availability: In stock

Package Price Qty
200 mg
$50.00
500 mg
$80.00
10mM * 1mL in DMSO
$50.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Biochanin A is an antiproliferative and anti-inflammatory agent that inhibits iNOS expression and lipopolysacharide (LPS)-induced nitric oxide production in macrophages. Additionally, Biochanin A displays the ability to block phosphorylation of IκBα and p38 MAPK, which prevents NF-κB activation. Furthermore, Biochanin A has been observed to suppress IL-6, IL-1β, and TNF-α production.

Targets
FAAH (rat) FAAH (mouse) FAAH (human) EGFR
1.4 μM1.8 μM2.4 μM91.5 μM
In vitro DMSO 57 mg/mL (200.52 mM)
Water <1 mg/mL (<1 mM)
Ethanol 9 mg/mL (31.66 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.17 mL 175.87 mL 351.74 mL
0.5 mM 7.03 mL 35.17 mL 70.35 mL
1 mM 3.52 mL 17.59 mL 35.17 mL
5 mM 0.7 mL 3.52 mL 7.03 mL

*The above data is based on the productmolecular weight 284.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10146
M. Wt 284.3
Formula C16H12O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 491-80-5
Synonyms 4-Methylgenistein
SMILES COC1=CC=C(C=C1)C2=COC3=CC(=CC(=C3C2=O)O)O

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy Biochanin A (4-Methylgenistein) | Biochanin A (4-Methylgenistein) Supplier | purchase Biochanin A (4-Methylgenistein) | Biochanin A (4-Methylgenistein) cost | Biochanin A (4-Methylgenistein) manufacturer | order Biochanin A (4-Methylgenistein) | Biochanin A (4-Methylgenistein) distributor | buy 491-80-5| 491-80-5 Supplier | purchase 491-80-5 | 491-80-5 cost | 491-80-5 manufacturer | order 491-80-5 | 491-80-5 distributor
Rewards