Others

FPH2 (BRD-9424) is a small molecule, which promotes differentiation of iPS-derived hepatocytes.

NB-598 is a potent competitive inhibitor of squalene epoxidase.

TH-237A is a novel neuroprotective agent, which possess protective properties against β-amyloid (Aβ)-induced neurodegeneration associated with Alzheimer's disease.

TRX-818 is a new, potent and multi-targeted anti-cancer agent in numerous human cancer cell lines.

Enhances differentiation of induced pluripotent stem cells (iPSCs) to hepatocytes; also promotes the maturation of iPSC-derived hepatocytes.

AZD7545 is a novel, selective small-molecule inhibitor of PDHK2 (PDH kinase2) with an IC50 of 36.8 nM and 6.4 nM for PDHK1 and PDHK2 respectively.

Ro 48-8071 is an inhibitor of OSC(Oxidosqualene cyclase; IC50=6.5 nM) that has low-density lipoprotein (LDL) cholesterol lowering activity.

Abscisic Acid is a plant hormone, which is involved in many plant developmental processes, modulates ion homeostasis and metabolism.

Amifostine is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.

Dicoumarol is a competitive NADH quinone oxidoreductase (NQO1) inhibitor.

Meclofenoxate HCl is an anti-aging drug used to treat the symptoms of senile dementia and Alzheimer's disease, and also inhibits the activity of cholinephosphotransferase.

L-Mimosine is a non-protein amino acid, and acts as an iron chelator.

MSDC-0160 is a prototype mTOT-modulating insulin sensitizer being studied to treat diabetes and Alzheimer's disease.

FPH1 is a small molecule, which promotes expansion of iPS-derived hepatocytes.

Ro 48-8071 inhibits cholesterol biosynthesis at the level of 2,3-oxidosqualene cyclase (OSC). It blocks OSC and cholesterol synthesis in HepG2 cells in the nanomolar range. A novel lipid lowering agent.

Isomalt is a sugar substitute, a type of sugar alcohol, used primarily for its sugar-like physical properties.

Jasmonic acid is derived from the fatty acid linolenic acid.

Tazarotenic Acid is the principle active metabolite of Tazarotene.

CAY10650 is a highly potent (IC50 = 12 nM) cPLA2α inhibitor.

PCI-27483 is a reversible small-molecule inhibitor of activated factor VII (factor VIIa) with potential antineoplastic and antithrombotic activities.

AB05831 is a highly potent and specific inhibitor of beta-hexosaminidase.

YL-109 has ability to inhibit breast cancer cell growth and invasiveness in vitro and in vivo.

Esonarimod is an antirheumatic drug, suppressing lymphocyte activating factor activity or biosynthesis.

GR148672X is a TGH inhibitor.

HAMNO, also known as NSC-111847, is a potent and selective inhibitor of replication protein A (RPA) interactions with proteins involved in the replication stress response.

ELN484228 is a cell-permeable alpha-Synuclein Blocker.

CPHPC is a divalent crosslinker of SAP that causes rapid depletion of circulating SAP via hepatic clearance. Serum amyloid P (SAP) is pentraxin with roles in inflammation and immune response.

Succimer is an orally active heavy metal chelator.

Pirinixil is a hypolipidemic agent of low toxicity.

Diflumidone is a non-steroidal antiinflammatory drug.

Anitrazafen is a topically effective antiinflammatory agent.

AMZ30 is a selective, covalent inhibitors of protein phosphatase methylesterase-1(PME-1) with IC50 value of 600 nM.

GJ-103 is an active analog of the read-through compound GJ072. CAS: 1459687-96-7 (Sodium salt) 1459687-89-8 (Free Acid)

EG01377 TFA salt is a selective neuropilin-1 (NRP1) antagonist. CAS: 2227996-00-9 (Free base)

MLS0315771 is a potent competitive phosphomannose isomerase (MPI) inhibitor.

Sulfabromomethazine, also known as Bromosulfamethazine, NSC 5874, SN 3517, is a long-acting derivative of sulfamezathine that is used in the poultry, swine and cattle industries for the treatment of coccidiosis.

KC01 is a covalent inhibitor of ABHD16A.

Chlorthalidone is a diuretic drug used to treat hypertension. It is described as a thiazide diuretic. Compared with other medications of the thiazide class, chlortalidone has the longest duration of action but a similar diuretic effect at maximal therapeutic doses. Chlortalidone is often used in the management of hypertension and edema. Chlorthalidone directly inhibits sodium and chloride reabsorption on the luminal membrane of the early segment in the distal convoluted tubule in the kidney. This leads to an increase in sodium, chloride, bicarbonate, and potassium secretion resulting in the excretion of water.

Felbinac is a potent non-steroidal anti-inflammatory agent, used to treat muscle inflammation and arthritis.

Phenethyl alcohol, or 2-phenylethanol, is the organic compound that consists of a phenethyl group group attached to OH. It is a colourless liquid that is slightly soluble in water, but miscible with most organic solvents.

Carbasalate Calcium, also known as Alcacyl and Omegin, is a non-steroidal anti-inflammatory drug used to treat pain and fever.

Metaxalone is a muscle relaxant used to relax muscles and relieve pain caused by strains, sprains, and other musculoskeletal conditions. It is considered to be a moderately strong muscle relaxant, with relatively low incidence of side effects. Metaxalone appears to interact with the cytochrome p450 system and may act as a general central nervous system depressant.

Oxaceprol is an antirheumatic Agent.

Anisindione (brand name Miradon) is a synthetic anticoagulant and an indanedione derivative. It prevents the formation of active procoagulation factors II, VII, IX, and X, as well as the anticoagulant proteins C and S, in the liver by inhibiting the vitamin K?Cmediated gamma-carboxylation of precursor proteins.

Suxibuzone is a analgesic used for joint and muscular pain. It is a prodrug of the non-steroidal anti-inflammatory drug phenylbutazone, and is commonly used in horses.

Bendroflumethiazide is a thiazide diuretic used to treat hypertension. Bendroflumethiazide works by inhibiting sodium reabsorption at the beginning of the distal convoluted tubule and may play an important role in the treatment of mild heart failure.

alpha-Tocopherol is one of the most abundant isoforms of vitamin E. alpha-Tocopherol is a biologically active liposoluble vitamin and potent antioxidant.

Laurocapram is a chemical enhancer for skin permeation of drug.

Propacetamol Hydrochloride is a prodrug of paracetamol (PCM), being effectively used to treat fever and pain.

Xanthinol niacinate is a combination of xanthinol and niacin which acts as a vasodilator.