Catalog No.
Product Name
Application
Product Information
Citations
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Ligand for E3 Ligase
CRBN ligand-411 is a small molecule ligand that targets the E3 ubiquitin ligase cereblon (CRBN), facilitating its recruitment to specific protein substrates. This compound can be utilized in the development of proteolysis targeting chimeras (PROTACs) by linking to a target protein ligand through a suitable linker. CRBN ligand-411 supports research in targeted protein degradation, enabling the investigation of cellular processes and therapeutic applications in various diseases. -
Ligand for E3 Ligase
CRBN ligand-699 is a small molecule ligand for the E3 ubiquitin ligase cereblon (CRBN). It facilitates the recruitment of the CRBN protein, enabling targeted degradation of specific proteins when linked to a target protein ligand through a suitable linker. This compound is instrumental in the development of PROTACs (proteolysis-targeting chimeras) for research applications focused on ubiquitin-mediated protein turnover and targeted therapy strategies. -
Ligand for E3 Ligase
CRBN ligand-755 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), functioning to selectively recruit the CRBN protein. This compound is designed for use in PROTAC (protasome-targeting chimeras) development, allowing for targeted protein degradation in cellular studies. Its ability to link to a target protein ligand via a linker opens avenues for manipulating protein levels in various biological research applications. -
Ligands for E3 Ligase
CRBN ligand-162 is a ligand for the CRBN-type E3 ubiquitin ligase, facilitating the targeted degradation of proteins through the ubiquitin-proteasome system. This compound is utilized in the design and synthesis of PROTACs (Proteolysis Targeting Chimeras), which are powerful tools for selective protein degradation in various biological research applications. Its utilization promotes advancements in understanding protein function and therapeutic interventions in diseases linked to protein dysregulation. -
Ligand for E3 Ligase
CRBN ligand-636 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to specific target proteins. This compound can be utilized in the design of PROTACs (Proteolysis Targeting Chimeras) by linking it to a target protein ligand through a linker, enabling targeted ubiquitination and degradation of the desired protein. CRBN ligand-636 is valuable in research applications aimed at exploring protein function, degradation pathways, and therapeutic interventions in various diseases. -
Ligand for E3 Ligase
CRBN ligand-571 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to specific target proteins. This compound can be utilized to synthesize PROTACs (proteolysis-targeting chimeras) by linking it to a target protein ligand through a suitable linker. Its distinctive mechanism of action makes it a valuable tool for probing protein degradation pathways and studying the dynamics of protein homeostasis in cellular systems. -
Ligand for E3 Ligase
CRBN ligand-616 functions as a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This reagent can be conjugated with a target protein ligand through a linker to generate a proteolysis-targeting chimeric molecule (PROTAC). It supports research in targeted protein degradation, offering potential applications in therapeutic development and cellular signaling studies. -
Ligand for E3 Ligase
CRBN ligand-631 is a potent ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound is instrumental in the design of PROTACs (Proteolysis Targeting Chimeras) by allowing the conjugation of a target protein ligand through a suitable linker. Its ability to modulate protein degradation pathways makes it valuable for research into targeted protein degradation and therapeutic applications. -
Ligand for E3 Ligase
CRBN ligand-209 is a potent ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the targeted recruitment of the CRBN protein. This compound can be conjugated to a specific target protein ligand through a linker, enabling the formation of PROTACs (proteolysis-targeting chimeras). It is valuable for research applications focused on targeted protein degradation and exploring protein turnover mechanisms within cellular systems. -
Ligand for E3 Ligase
CRBN ligand-418 is a novel ligand for the E3 ubiquitin ligase cereblon (CRBN). This compound is designed to facilitate the recruitment of CRBN to target proteins when conjugated via a linker, thereby enabling the formation of Proteolysis Targeting Chimeras (PROTACs). Its application in targeted protein degradation offers significant potential in therapeutic research and development. -
Ligand for E3 Ligase
CRBN ligand-695 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of this protein in targeted protein degradation applications. It can be conjugated with a target protein ligand through a linker to create a PROTAC, enabling the selective degradation of specific proteins. This compound is valuable for research focused on targeted therapeutics and the manipulation of cellular protein levels. -
Ligand for E3 Ligase
CRBN ligand-687 is a small molecule ligand that targets the E3 ubiquitin ligase cereblon (CRBN). It is designed to facilitate the recruitment of cereblon to specific target proteins, enabling the formation of PROTACs (Proteolysis Targeting Chimeras). This compound is valuable for studies related to targeted protein degradation and offers potential applications in therapeutic development. -
Ligand for E3 Ligase
CRBN ligand-614 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound can be conjugated to a target protein ligand via a linker, enabling the formation of a proteolysis-targeting chimeric molecule (PROTAC). CRBN ligand-614 is valuable for research applications in targeted protein degradation and the study of ubiquitin-proteasome pathway mechanisms. -
Ligand for E3 Ligase
CRBN ligand-354 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. This compound can be utilized in targeted protein degradation approaches, such as the development of PROTACs, by linking it to a target protein ligand through a suitable linker. Its role in protein homeostasis and degradation pathways makes it valuable for studying therapeutic mechanisms in various biological contexts. -
Ligand for E3 Ligase
CRBN ligand-437 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN) that facilitates the assembly of CRBN with target proteins. This compound can be utilized in the design of PROTACs (proteolysis-targeting chimeras) by linking it to a target protein ligand through a suitable linker. Research applications include studies on protein degradation pathways and the development of targeted protein degradation strategies for therapeutic purposes. -
Ligand for E3 Ligase
CRBN ligand-889 is a ligand for the E3 ubiquitin ligase cereblon (CRBN) that facilitates the recruitment of CRBN to target proteins. This compound can be conjugated with a target protein ligand through a linker, allowing the formation of a PROTAC (proteolysis-targeting chimera). CRBN ligand-889 is instrumental in studying protein degradation pathways and the development of targeted therapies leveraging the ubiquitin-proteasome system. -
Ligand for E3 Ligase
CRBN ligand-250 is a specific ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein in targeted protein degradation applications. This compound can be conjugated to target protein ligands through a linker to create a PROTAC (proteolysis-targeting chimera), allowing for the selective degradation of substrate proteins. Its utility in research encompasses the study of protein homeostasis and therapeutic interventions in various diseases. -
Ligand for E3 Ligase
CRBN ligand-380 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN). This compound facilitates the recruitment of cereblon, enabling the targeted degradation of specific proteins through the formation of PROTACs (Proteolysis Targeting Chimeras). CRBN ligand-380 is instrumental in research applications aimed at exploring targeted protein degradation and ubiquitin-mediated proteolysis. -
Ligand for E3 Ligase
CRBN ligand-408 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound is pivotal for the development of proteolysis-targeting chimeras (PROTACs) by linking target protein ligands through a suitable linker. It is useful in studying the modulation of protein degradation pathways and exploring the therapeutic potential of targeted protein degradation. -
Ligand for E3 Ligase
CRBN ligand-698 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound can be utilized in the construction of PROTACs (proteolysis-targeting chimeras) by linking to a target protein ligand through a suitable linker. It is valuable in studies of targeted protein degradation and offers potential applications in drug discovery and development. -
Ligand for E3 Ligase
CRBN ligand-712 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of this essential protein. By utilizing CRBN ligand-712, researchers can effectively create PROTACs (Proteolysis Targeting Chimeras) by linking it to target protein ligands through a suitable linker. This compound is instrumental in studies focused on targeted protein degradation and the modulation of protein levels within cells, providing valuable insights into cellular processes and therapeutic applications. -
Ligand for E3 Ligase
CRBN ligand-740 is a small molecule ligand that targets the E3 ubiquitin ligase cereblon (CRBN). It facilitates the recruitment of CRBN, enabling the formation of targeted protein degraders, or PROTACs, through conjugation with specific target protein ligands via a linker. This compound is valuable in the study of protein degradation pathways and offers a tool for research applications in therapeutic development focused on targeted protein modulation. -
Ligand for E3 Ligase
CRBN ligand-641 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), known for its role in targeted protein degradation. This compound facilitates the recruitment of CRBN to target proteins when conjugated with a suitable ligand through a linker, enabling the development of PROTACs. Its applications span drug discovery and therapeutic development, particularly in cancer research and the modulation of protein levels within cellular pathways. -
Ligand for E3 Ligase
CRBN ligand-481 is a potent ligand for the E3 ubiquitin ligase cereblon (CRBN). This compound effectively recruits CRBN, facilitating the degradation of target proteins through the mechanism of proteolysis-targeting chimeras (PROTACs). Its application in research includes the development of novel therapeutic strategies targeting specific proteins for degradation, making it a valuable tool for studies in protein regulation and cellular homeostasis. -
Ligand for E3 Ligase
CRBN ligand-487 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. It can be utilized in the design of PROTACs (proteolysis-targeting chimeras) by linking to a target protein ligand via a suitable linker. This compound is valuable in studies focused on targeted protein degradation and the modulation of cellular pathways through ubiquitination. -
Ligand for E3 Ligase
CRBN Ligand-539 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. It serves as a crucial component in the development of proteolysis-targeting chimeras (PROTACs) by enabling the conjugation of target protein ligands through a linker. This functionality allows researchers to selectively degrade proteins of interest, providing valuable insights into protein regulation and cellular pathways. -
Ligand for E3 Ligase
CRBN ligand-558 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound can be conjugated with a target protein ligand through a linker to create a PROTAC, which can be utilized in targeted protein degradation research and therapeutic development. Its ability to modulate protein levels by facilitating ubiquitination makes it a valuable tool in cellular and molecular biology studies. -
Ligand for E3 Ligase
CRBN ligand-716 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. This compound can be utilized in the development of proteolysis-targeting chimeras (PROTACs) by linking it to a target protein ligand via a suitable linker. Its primary application includes targeted protein degradation, contributing valuable insights into protein regulation and therapeutic interventions. -
Ligand for E3 Ligase
CRBN ligand-494 is a ligand for the E3 ubiquitin ligase cereblon (CRBN) that facilitates the recruitment of the CRBN protein. This compound can be conjugated to a target protein ligand through a linker, enabling the formation of a PROTAC (proteolysis targeting chimera). Its application in targeted protein degradation research makes it a valuable tool for studying protein regulation and therapeutic interventions in cellular pathways. -
Ligand for E3 Ligase
CRBN ligand-583 is a small molecule ligand that targets the E3 ubiquitin ligase cereblon (CRBN). It is designed to facilitate the recruitment of CRBN to specific target proteins. By being conjugated to a target protein ligand through a linker, CRBN ligand-583 can be utilized in the development of PROTACs (Proteolysis-targeting chimeras) for targeted protein degradation studies and therapeutic applications in cancer and other diseases. -
Ligand for E3 Ligase
CRBN ligand-727 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), serving to selectively recruit the cereblon protein. This compound can be conjugated to a target-specific protein ligand through a linker, facilitating the creation of a proteolysis-targeting chimera (PROTAC). Its applications lie in targeted protein degradation studies, enabling the investigation of protein function and modulation within various biological systems. -
Ligand for E3 Ligase
CRBN ligand-291 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), functioning by selectively recruiting the CRBN protein. It serves as a valuable component in the construction of PROTACs (proteolysis-targeting chimeras) when linked to a target protein ligand via a suitable linker. This compound is essential for studies focused on targeted protein degradation and elucidating cellular mechanisms involving the ubiquitin-proteasome system. -
Ligand for E3 Ligase
CRBN ligand-379 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound can be conjugated to a target protein ligand using a linker to create a PROTAC, enabling targeted protein degradation. Its applications in drug discovery and cellular research make it an invaluable tool for studying protein homeostasis and therapeutic interventions. -
Ligand for E3 Ligase
CRBN ligand-388 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound can be conjugated to a target protein ligand through a linker to create a PROTAC, enabling selective degradation of specific proteins in cellular contexts. It serves as a valuable tool in research applications focused on targeted protein degradation and modulating protein levels within various biological systems. -
Ligand for E3 Ligase
CRBN ligand-526 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound can be employed in the development of PROTACs (proteolysis targeting chimeras) by linking it to a target protein ligand through a suitable linker. Research applications include targeted protein degradation studies, enabling the exploration of novel therapeutic strategies in various disease models. -
Ligand for E3 Ligase
CRBN ligand-610 is a specific ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein to target proteins. This compound can be conjugated to a target protein ligand through a linker, enabling the development of PROTACs (proteolysis-targeting chimeras) for targeted protein degradation applications. It is a valuable tool for researchers studying ubiquitin-proteasome pathway modulation and targeted therapeutics. -
Ligand for E3 Ligase
CRBN ligand-258 is a ligand specifically designed for the E3 ubiquitin ligase cereblon (CRBN). This compound facilitates the recruitment of cereblon to target proteins, enabling the formation of targeted protein degradation chimeras (PROTACs) when linked with an appropriate target ligand. It serves as a valuable tool in drug discovery and development by promoting the ubiquitin-proteasome pathway for selective protein degradation. -
Ligand for E3 Ligase
CRBN ligand-360 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. This compound can be conjugated with a target protein ligand through a linker, enabling the formation of a PROTAC (proteolysis-targeting chimera). It is suitable for applications in targeted protein degradation research and studies involving ubiquitin-proteasome system modulation. -
Ligand for E3 Ligase
CRBN ligand-347 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN). It effectively recruits the cereblon protein, facilitating the targeted degradation of proteins through the proteasome pathway. This compound is commonly employed in PROTAC (proteolysis-targeting chimera) applications, allowing researchers to develop bifunctional molecules that selectively degrade specific target proteins in various biological contexts. -
Ligand for E3 Ligase
CRBN ligand-316 functions as a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound is particularly useful in the development of Proteolysis Targeting Chimeras (PROTACs) by linking to target protein ligands through a suitable linker. Its application in targeted protein degradation makes it a valuable tool in chemical biology and therapeutic research. -
Ligand for E3 Ligase
CRBN ligand-752 is a ligand specifically designed for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound can be conjugated to a target protein ligand through a linker, enabling the formation of a PROTAC (proteolysis-targeting chimera). Its application in targeted protein degradation research offers valuable insights into cell signaling and disease mechanisms. -
Ligand for E3 Ligase
CRBN ligand-362 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. This compound serves as a crucial component in the development of PROTACs (proteolysis-targeting chimeras), enabling targeted protein degradation. Its application is vital for research into targeted therapies and the modulation of protein levels in cellular contexts. -
Ligand for E3 Ligase
CRBN ligand-768 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), enabling the recruitment of the cereblon protein. This compound can be conjugated to a target protein ligand through a linker to create a Proteolysis Targeting Chimera (PROTAC). It serves as a valuable tool in the study of targeted protein degradation and has potential applications in drug discovery and therapeutic development. -
Ligand for E3 Ligase
CRBN ligand-705 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN). This compound effectively recruits the CRBN protein and can be utilized to create peptide-hybrid PROTACs when linked to a target protein ligand through a suitable linker. Its application in protein degradation research provides valuable insights into targeted protein modulation and therapeutic development. -
Ligand for E3 Ligase
CRBN ligand-353 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. This compound can be utilized in the design of PROTACs (Proteolysis Targeting Chimeras) by covalently linking it to a target protein ligand via a suitable linker. It is valuable in studies focused on targeted protein degradation and modulation of cellular pathways mediated by ubiquitination. -
Ligand for E3 Ligase
CRBN ligand-378 is a specific ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. This compound can be conjugated to target protein ligands through a linker, enabling the formation of proteolysis-targeting chimeras (PROTACs). It is valuable for research applications focused on targeted protein degradation and modulation of cellular pathways. -
Ligand for E3 Ligase
CRBN ligand-599 is a potent ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. This compound can be utilized in the design of proteolysis-targeting chimeras (PROTACs) by linking it to specific target protein ligands through a suitable linker. Its applications include studying targeted protein degradation mechanisms and potential therapeutic interventions in protein homeostasis-related diseases. -
Ligand for E3 Ligase
CRBN ligand-595 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. This compound can be conjugated to a target protein ligand through a linker, enabling the formation of a proteolysis-targeting chimera (PROTAC). CRBN ligand-595 is valuable for studies in targeted protein degradation and E3 ligase-mediated ubiquitination pathways. -
Ligand for E3 Ligase
CRBN ligand-622 is a potent ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound can be conjugated to a target protein ligand through a linker to create a proteolysis-targeting chimera (PROTAC). Its use in research enables the selective degradation of specific proteins, thereby aiding investigations into protein regulation and therapeutic applications. -
Ligand for E3 Ligase
CRBN ligand-787 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to specific target proteins. This compound can be utilized in the development of proteolysis-targeting chimeras (PROTACs) by linking it to a ligand for the target protein, enabling targeted degradation via the ubiquitin-proteasome system. CRBN ligand-787 is valuable in research applications focused on protein regulation and degradation mechanisms.
