Catalog No.
Product Name
Application
Product Information
Citations
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calcium channel blocker
Isradipine is a calcium channel blocker of the dihydropyridine class.- Deborah A. Goldspink, .et al. , Mol Metab, 2018, Jan; 7: 90-101 PMID: 29167062
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Selective calcium chelator
BAPTA/AM, an intracellular calcium chelator, induces delayed necrosis by lipoxygenase-mediated free radicals in mouse cortical cultures.- Maohuan Ran, .et al. , Ecotoxicol Environ Saf, 2026, May:316:120163 PMID: 42013791
- Jian Sun, .et al. , Nanoscale, 2024, Dec 17 PMID: 39688368
- Jiunn-Chang Lin, .et al. , Toxicol Appl Pharmacol, 2023, Jul 15;471:116568 PMID: 37245555
- Liying Wu, .et al. , Phytother Res, 2022, Feb;36(2):938-950 PMID: 35076979
- Shichen Xu, .et al. , Cell Signal, 2020, Aug 6;75:109733 PMID: 32771398
- Miho Akimoto, .et al. , Cell Death Dis, 2018, Aug; 9(8): 804 PMID: 30038429
- Zhang L, .et al. , Medicine (Baltimore), 2018, Jun;97(24):e11095 PMID: 29901626
- Manidipine 2HCl is a HCl salt form of Manidipine which is a calcium channel blocker for Ca2+ current with IC50 of 2.6 nM.
- Noriaki Ikemura,, .et al. , Chem -Biol Interact, 2019, 306:1-9 PMID: 30965050
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Calcium Channel inhibitor
Nimodipine is a L-type Ca2+ channel blocker.- Shiqian Han, .et al. , iScience, 2023, Apr 8;26(5):106613 PMID: 37128603
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Calcium channel blocker
Mibefradil is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels displaying IC50s of 2.7 μM and 18.6 μM for T-type and L-type currents, respectively. -
Calcium channel blocker
Mibefradil 2Hcl is calcium channel blocker with moderate selectivity for T-type Ca2+ channels displaying IC50 values of 2.7 uM and 18.6 uM for T-type and L-type channels respectively. - N-type calcium channel blocker-1 is an orally active analgesic agent which shows high affinity to functionally block N-type calcium channels with an IC50 of 0.7 μM in the IMR32 assay.
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T-type Ca2+ channel blocker
ABT-639 hydrochloride is a novel, peripherally acting, selective T-type Ca2+ channel blocker. - Pinaverium Bromide is a spasmolytic agent with low incidence of anticholinergic effects. Pinaverium Bromide is also an antispasmodic.
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glutamate release inhibitor
Sipatrigine, a neuroprotective agent, is a glutamate release inhibitor, voltage-dependent sodium channel and calcium channel inhibitor, penetrating the central nervous system. Has potential to treat focal cerebral ischemia and stroke. -
dihydropyridine calcium entry blocker
Lemildipine is a new dihydropyridine calcium entry blocker. -
Calcium channel blocker
Amlodipine aspartic acid impurity is the impurity of Amlodipine aspartic acid. Amlodipine aspartic acid is a calcium channel blocker with antihypertensive and antianginal properties. -
calcium channel blocker
Azelnidipine is a calcium blocker that attenuates liver fibrosis and may increase antioxidant defence. that attenuates liver fibrosis and may increase antioxidant defence. -
Ca2+ signaling modulator
Astragaloside A is a novel regulator of HIF-1α and angiogenesis through the PI3K/Akt pathway in HUVECs that are exposed to hypoxia. - Benidipine hydrochloride is a long-acting T-type calcium channel blocker, on blood pressure and renal function in hypertensive patients with diabetes mellitus.
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calcium channel blocker
Nilvadipine is a calcium channel blocker (CCB) used for the treatment of hypertension and chronic major cerebral artery occlusion -
Calcium channel blocker
Clevidipine is a dihydropyridine calcium channel blocker indicated for the reduction of blood pressure when oral therapy is not feasible or not desirable. -
Ca2+ channel agonist/CDK2 inhibitor
Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2, with EC50s of 14.23 μM and 3.34 μM, respectively, and is used as a potential treatment for motor nerve terminal dysfunction. - Atagabalin is related to gabapentin, which similarly binds to the α2δ calcium channels (1 and 2).
- CRAC intermediate 2 is a intermediate compound for CRAC inhibitor synthesis, extracted from patent WO 2013059666A1.
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Ca2+ release inhibitor
Dantrolene sodium is a muscle relaxant that acts by abolishing excitation-contraction coupling in muscle cells, probably by action on the ryanodine receptor. -
Selective calcium chelator
BAPTA tetrapotassium is a selective calcium chelator with greater affinity for Ca2+ than Mg2+. -
SERCA inhibitor
Cyclopiazonic acid is an inhibitor of SERCA (endoplasmic reticulum Ca2+-ATPase) which induces the release of intracellular stored Ca2+, without increasing IP3 levels. -
Calcium channel blocker
Efonidipine is a dihydropyridine calcium channel blocker that blocks both T-type and L-type calcium channels. It has also been studied in atherosclerosis and acute renal failure. -
Calcium channel blockers
Nicardipine(YC-93) is a calcium channel blocker that has been widely used to control blood pressure in severe hypertension following events such as ischemic stroke, traumatic brain injury, and intracerebral hemorrhage. -
Calcium channel blocker
Fendiline hydrochloride is a nonselective calcium channel blocker. -
Calcium channel proteins inhibitor
Dantrolene sodium is a inhibitor of calcium channel proteins, inhibiting the release of Ca2+ from the sarcoplasm. Dantrolene sodium is a skeletal muscle relaxant which acts by blocking muscle contraction beyond the neuromuscular junction. - Trimethadione is an oxazolidinedione anticonvulsant. It is most commonly used to treat epileptic conditions that are resistant to other treatments. Trimethadione (TMO) has the properties required of probe drugs for the evaluation of hepatic drug-oxidizing capacity in humans in vivo.
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Calcium channel blocker
Lercanidipine is a calcium channel blocker of the dihydropyridine class, which works by relaxing and opening the blood vessels allowing the blood to circulate more freely around the body. This lowers the blood pressure and allows the heart to work more efficiently. -
calcium channel blocker
Bepridil hydrochloride (CERM 1978) is a calcium channel blocker, with antianginal activity. -
dual T-type and L-type calcium channel blocker
Efonidipine hydrochloride monoethanolate (NZ-105 hydrochloride monoethanolate) is a dual T-type and L-type calcium channel blocker (CCB). -
L-type calcium-channel antagonist
Etripamil (MSP-2017) is a short-acting L-type calcium-channel antagonist with a rapid onset of action designed for intranasal administration, used to treat Paroxysmal Supraventricular Tachycardia (PSVT). Etripamil (MSP-2017) slows atrioventricular nodal conduction and prolongs atrioventricular nodal refractory periods by inhibiting calcium ion influx through the calcium slow channels in the atrioventricular node cells. -
Calcium channel antagonist
Aranidipine (MPC1304) is a Ca2+ channel antagonist with potent and long-lasting antihypertensive effects. -
Calcium Channel Activator
Bay K 8644 is a potent, selective activator of L-type Ca2+ channel with IC50 of 17.3 nM. - Dantrolene sodium Hemiheptahydrate is a skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber.
- Cinepazide maleate is a maleate salt form of cinepazide which is a vasodilator.
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calcium channel blocker
Cinnarizine is a medication derivative of piperazine, and characterized as an antihistamine and a calcium channel blocker. -
Calcium Channel /TRP5 antagonist
Lomerizine dihydrochloride is a antagonist at L-type and T-type Ca 2+ channels and TRp5 channels used to treat migraines and vertigo. -
calcium channel blocker
Nicardipine hydrochloride (YC-93) is a calcium channel blocker with an IC50 of 1 μM for blocking cardiac calcium channels. -
elastogenesis inhibitor
L-Ascorbic acid sodium salt (Sodium L-ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid sodium salt inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid sodium salt is also a collagen deposition enhancer and an elastogenesis inhibitor. - Coelenterazine h is a derivative of Coelenterazine. Coelenterazine h is more sensitive to Ca2+ than is the native complex, thus providing a valuable tool for measuring small changes in Ca2+ concentrations.
