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Biological Activity
CDN1163 is a SERCA2 allosteric activator. It increases Ca2+-ATPase activity and Ca2+ uptake by ER microsomes from obese mice. Rescues HEK cells from ER stress-induced cell death.
| In vitro | DMSO | 63 mg/mL (196.63 mM) | |
| Water | Insoluble | ||
| Ethanol | 63 mg/mL (196.63 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.21 mL | 156.06 mL | 312.13 mL |
| 0.5 mM | 6.24 mL | 31.21 mL | 62.43 mL |
| 1 mM | 3.12 mL | 15.61 mL | 31.21 mL |
| 5 mM | 0.62 mL | 3.12 mL | 6.24 mL |
*The above data is based on the productmolecular weight 320.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16951 |
|---|---|
| Actions | Activator |
| CAS No. | 892711-75-0 |
| Formula | C20H20N2O2 |
| M. Wt | 320.38 |
| Purity | >98% |
| Synonyms | CDN 1163, CDN-1163 |
| SMILES | O=C(NC1=C2N=C(C)C=CC2=CC=C1)C3=CC=C(OC(C)C)C=C3 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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