Catalog No.
Product Name
Application
Product Information
Citations
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Drug Impurity
Brimonidine impurity 3 is a chemical impurity associated with the drug Brimonidine, primarily targeting adrenergic receptors. This compound is relevant for quality control in pharmaceutical formulations and can be utilized to study the stability and degradation pathways of Brimonidine. Its characterization contributes to the development of safer and more effective drug products. -
Drug Impurity
Carvedilol impurity 13 is a known impurity of the beta-blocker carvedilol, which primarily targets beta-adrenergic receptors. This compound is utilized in pharmaceutical research to assess the purity and stability of carvedilol formulations. Its characterization is essential for ensuring compliance with regulatory standards and improving drug quality. -
Intermediate
2-Benzylaniline is an intermediate compound that serves as a precursor in the synthesis of Compound 15. This derivative exhibits affinity for the D3 dopamine receptor, with a Ki value of 4654 nM. 2-Benzylaniline is valuable in research related to mental disorders, enabling the exploration of therapeutic targets within neuropharmacology. -
Impurity of Asenapine
Asenapine impurity 1 is a recognized impurity of Asenapine, an atypical antipsychotic known for its antagonistic activity on serotonin, adrenoceptors, dopamine, and histamine receptors. With reported pKi values ranging from 8.2 to 10.5 across these targets, it is relevant for studies investigating the pharmacological profile of Asenapine. This impurity is important for quality control and characterization in research contexts focused on schizophrenia and bipolar disorder treatments. -
Drug Impurity
Brexpiprazole impurity 1 is a chemical impurity related to the atypical antipsychotic Brexpiprazole, which primarily targets serotonin and dopamine receptors. This impurity can be utilized in the assessment of drug quality and to investigate the stability and degradation pathways of Brexpiprazole. Its presence may influence the pharmacological profile and safety evaluations in related research applications. -
α1 Adrenergic Receptor Agonist
Phenylephrine hydrochloride is an α1 adrenergic receptor agonist primarily used as a sympathomimetic agent. It induces vasoconstriction and increases perfusion pressure, making it valuable in clinical settings for managing hypotension and as a decongestant. Researchers utilize Phenylephrine hydrochloride to study cardiovascular responses and the pharmacological effects of adrenergic activation in various biological systems. -
Drug Intermediate
1-epi-Regadenoson ethyl ester is a key intermediate in the synthesis of the α-isomer impurity of Regadenoson, a highly selective agonist for the adenosine A2A receptor. This compound is essential for research involving adenosine receptor biology and contributes to the understanding of cardiovascular function and cellular signaling pathways. Its application extends to the development and analysis of therapeutic agents targeting adenosine receptors. -
Synthetic Cannabinoid
5-Fluoropentylindole serves as a synthetic cannabinoid that primarily targets cannabinoid receptors in the central nervous system. This compound exhibits significant affinity for CB1 receptors, making it a valuable tool for studying the endocannabinoid system and its associated signaling pathways. 5-Fluoropentylindole is applicable in pharmacological research and may aid in investigating the effects of synthetic cannabinoids on physiological processes and potential therapeutic outcomes. -
Drug Intermediate
1-epi-Regadenoson hydrazone serves as a crucial intermediate in the synthesis of the α-isomer impurity of Regadenoson, a selective adenosine A2A receptor agonist. Its role in the development of this compound is significant for research in cardiovascular pharmacology and adenosine receptor modulation. This reagent is essential for investigations into therapeutic applications targeting the A2A receptor pathway. -
Drug Impurity
Mirabegron impurity 10 is a known impurity associated with the pharmacological agent Mirabegron, a selective beta-3 adrenergic receptor agonist. It is crucial for studies focused on drug purity and stability, as well as for understanding the synthesis and degradation pathways of Mirabegron. This impurity serves as a reference standard for analytical methods and quality control processes in pharmaceutical development and research applications. -
Drug Impurity
Salbutamol impurity 7 is a known impurity of the bronchodilator Salbutamol, which primarily targets beta-2 adrenergic receptors. This compound is important for analytical research and quality control in pharmaceutical development to ensure the purity and safety of Salbutamol formulations. Its presence can influence pharmacokinetics and therapeutic efficacy, making it relevant for studies focused on drug metabolism and impurities. -
Drug Impurity
Paliperidone impurity 3 is a known impurity of the antipsychotic agent Paliperidone, which primarily targets dopamine receptors. This compound is utilized in pharmaceutical research for quality control and to assess the purity of Paliperidone formulations. It serves as a crucial reference standard in the development and validation of analytical methods, ensuring compliance with regulatory standards in drug production. -
Drug Intermediate
2,6-Dichloropurine is a pharmaceutical intermediate primarily utilized in the synthesis of various drug candidates. This compound plays a key role in the development of phosphodiesterase (PDE) inhibitors, human A3 adenosine receptor antagonists, and cyclin-dependent kinase (CDK) inhibitors. Its versatile chemical structure makes it a valuable reagent in biomedical research and pharmaceutical development. -
Drug Intermediate
Fmoc-Lys(tBuO-Ara-Glu(AEEA-AEEA)-OtBu)-OH is a key drug intermediate in the synthesis of Tirzepatide, which functions as a dual agonist of the glucose-dependent insulinotropic peptide (GIP) and the glucagon-like peptide-1 receptor (GLP-1R). This compound is essential for research and development in diabetes therapeutics, as Tirzepatide enhances insulin secretion and improves glycemic control. Its structural features facilitate the exploration of peptide-based treatments for metabolic disorders. -
Piperazine
1-Benzyl-3-methylpiperazine is a piperazine derivative that primarily functions as a monoamine receptor ligand. It exhibits significant activity at various serotonin and dopamine receptors, making it a valuable compound for research in neuropharmacology. This reagent is often utilized in studies exploring the effects of psychoactive substances and the mechanisms underlying mood regulation. -
Piperazine
MDBP hydrochloride is a piperazine derivative that acts as a central nervous system modulator. It demonstrates significant biological activity by influencing serotonin and dopamine receptors, making it a valuable tool for neuroscience research. This compound is useful for investigating psychiatric disorders and exploring the pharmacological effects of piperazine analogs. -
Derivative of Clonidine
Acetylclonidine is a derivative of Clonidine that targets imidazoline and adrenergic receptors. It exhibits biological activity in reducing intraocular pressure, making it a valuable reagent for research into ocular antihypertensive agents for the treatment of glaucoma. Its unique profile may provide insights into novel therapeutic approaches in ocular health. -
Amisulpride Photodegradation Product
Amisulpride N-oxide is a photodegradation product of Amisulpride, which acts as a dopamine D2/D3 receptor antagonist. This compound may be relevant for studies investigating the stability and degradation pathways of Amisulpride under light exposure. Its characterization can aid researchers in understanding the pharmacokinetics and metabolic processes associated with dopamine receptor modulation. -
Aminoalkylindole Derivative
7'-Methoxy NABUTIE is a derivative of aminoalkylindole that primarily targets cannabinoid receptors. This compound is recognized for its potential biological activity in modulating the effects associated with alcohol consumption. Research applications include investigations into the pathways of alcohol abuse and the exploration of therapeutic strategies for addiction. -
Platelet Aggregation Inhibitor
4-Trifluoromethylsalicylic acid, also known as Desacetyl triflusal, functions as a platelet aggregation inhibitor. This compound is instrumental in research related to cardiovascular disorders, particularly in the study of thrombus formation and prevention. Its ability to modulate platelet activity makes it a valuable tool for investigating hematological processes and developing antithrombotic therapies. -
Tetrahydrocannabinol Analogues
8-Oxo-Δ9-THC is an oxygenated analog of tetrahydrocannabinol that exhibits significant interaction with cannabinoid receptors in the endocannabinoid system. This compound demonstrates notable biological activity, which may influence various cellular signaling pathways involved in pain modulation, inflammation, and neuroprotection. Its potential applications include research into therapeutic effects associated with cannabinoid compounds as well as studies investigating the pharmacological properties of cannabis-derived substances. -
Desfluorinated Nebivolol Isomer
Desfluoro nebivolol is a desfluorinated isomer of the antihypertensive agent nebivolol, primarily acting as a beta-adrenergic receptor blocker. This compound exhibits pharmacological activity related to cardiovascular regulation, making it relevant for research in hypertension and heart failure therapies. Its unique chemical structure allows for exploration of β-blockade mechanisms and potential therapeutic benefits, providing valuable insights for the development of cardiovascular treatments. -
Piperazine
2-BZP is a piperazine compound that functions as a central nervous system stimulant by targeting serotonin and dopamine receptors. Its primary biological activity includes modulation of neurotransmitter release, making it useful in research related to neuropharmacology and behavioral studies. 2-BZP serves as a valuable tool for elucidating the mechanisms of psychostimulant effects and exploring potential therapeutic applications. -
Drug Derivative
Cetamolol is a drug derivative that primarily targets beta-adrenergic receptors. It exhibits significant cardioprotective effects and is utilized in research focusing on cardiovascular pharmacology. Its ability to modulate heart rate and blood pressure makes it valuable for investigating hypertension and related cardiovascular disorders. -
Piperazine
1-(3-Chloro-4-fluorophenyl)piperazine hydrochloride is a piperazine derivative that acts as a potent and selective modulator of various neurotransmitter systems. This compound is primarily utilized in neuroscience research to investigate its effects on serotonin and dopamine receptors, contributing to the understanding of mood disorders and psychotropic drug action. Its unique chemical structure makes it valuable for studies related to pharmacology and medicinal chemistry. -
Drug Derivative
1(R)-Tetrahydrocannabidiol is a drug derivative known for its interaction with cannabinoid receptors. It exhibits potential neuroprotective activity, making it a valuable tool for investigating neurological diseases and disorders. This compound facilitates research into the therapeutic effects of cannabinoids in various neurobiological contexts. -
Antiplatelet Aggregation Agent
Imolamine is a potent antiplatelet aggregation agent that functions through the modulation of platelet activation pathways. As a phenyl aminoxidiazole derivative, it demonstrates significant anti-thrombotic activity, making it a valuable tool for studying platelet biology and associated disorders. This compound is relevant for research into coronary heart disease and other cardiovascular conditions where platelet aggregation plays a critical role. -
Drug Derivative
TA-993 is a drug derivative that enhances limb blood flow primarily through the modulation of the sympathetic nervous system, bypassing adrenergic receptors. This compound demonstrates a distinctive mechanism of action, potentially influencing heart rate through alternative pathways. TA-993 is valuable for research applications focused on understanding vascular dynamics and autonomic control in various physiological and pathological states. -
Active Molecule
WAY-271999 is an active molecule that serves as a potent antagonist of the cannabinoid receptor type 1 (CB1). It exhibits significant modulation of neuropsychiatric and metabolic processes, making it a valuable tool for research in obesity, addiction, and mood disorders. This compound is suitable for in vitro and in vivo studies aimed at elucidating the role of CB1 signaling in various physiological and pathological conditions. -
Drug Derivative
Benzoadenosine is a drug derivative that acts as an adenosine receptor modulator. It exhibits biological activities that may influence cellular signaling pathways involving adenosine, making it valuable for research in pharmacology and drug development. This compound can be utilized to investigate the role of adenosine-related mechanisms in various biological processes and disease states. -
Vasoconstrictor Agent
Nordefrin, a derivative of norepinephrine, functions primarily as a vasoconstrictor agent. It exerts its biological activity by stimulating adrenergic receptors, leading to increased vascular resistance and elevated blood pressure. This compound is commonly utilized in research investigations focused on cardiovascular physiology and pharmacology, particularly those exploring blood pressure regulation and vascular function. -
Platelet Aggregation Inhibitor
Ataprost is a potent platelet aggregation inhibitor that functions as an orally active analogue of Carboprostacyclin. This compound demonstrates 2.6 times greater efficacy than Carboprostacyclin in inhibiting ADP-induced platelet aggregation in vitro. Additionally, Ataprost has been shown to alleviate coronary spasm, making it relevant for research in cardiovascular diseases and platelet function studies. -
Guanfacine Derivative
Etiguanfacine is a derivative of Guanfacine that primarily targets alpha-2 adrenergic receptors. It exhibits potential for reducing gastrointestinal side effects commonly associated with Guanfacine, making it a valuable tool for research into improved therapeutic profiles. This compound can be utilized in studies involving hypertension and attention-deficit hyperactivity disorder (ADHD), as well as in evaluating receptor-mediated mechanisms in neuropharmacology. -
Drug Derivative
Fepradinol is a drug derivative that primarily acts as a selective modulator of adrenergic receptors. This compound exhibits significant biological activity in influencing cardiovascular responses and can be utilized in research focused on cardiovascular pharmacology. Its modulatory effects make it valuable for investigating the therapeutic potential in treating various cardiovascular disorders. -
Drug Derivative
Methoserpidine is a drug derivative that primarily functions as an antagonist of the alpha-adrenergic receptor. This compound exhibits significant biological activity in modulating cardiovascular responses and neurotransmitter release, making it useful for research in hypertension and other cardiovascular disorders. Its properties enable exploration of adrenergic signaling pathways and may provide insights into potential therapeutic strategies. -
Dexoxadrol Enantiomer
Levoxadrol is the active enantiomer of dexoxadrol, primarily targeting adrenergic receptors. This compound exhibits potent agonistic activity, making it valuable for research applications in cardiovascular and neuropharmacology studies. Its distinct biological properties facilitate investigations into adrenergic signaling pathways and their role in various physiological and pathological conditions. -
Cannabinoid Compound
Δ8-THCO (delta 8-tetrahydrocannabinol) is a cannabinoid compound derived from Cannabis sativa. This compound exhibits psychoactive properties akin to delta-9-THC, engaging with the CB1 cannabinoid receptor, which is implicated in various physiological processes such as appetite, pain sensation, and mood regulation. Δ8-THCO is utilized in research focused on understanding the effects of cannabinoids on the endocannabinoid system and exploring potential therapeutic applications in pain management and anxiety treatment. -
Peptide
Cionin is a disulfotyrosyl hybrid peptide derived from cholecystokinin and gastrin. It primarily targets cholecystokinin receptors, mediating various physiological functions such as gastric motility and enzyme secretion. This compound is utilized in research applications examining gastrointestinal physiology and the endocrine system. Its unique structure allows for the exploration of receptor interactions and signaling pathways in peptide studies. -
Nasal Vasoconstrictor
Tymazoline hydrochloride is an imidazoline derivative known for its nasal vasoconstrictor properties. It acts primarily on alpha-adrenergic receptors, leading to the reduction of nasal mucosal edema. This compound is valuable in research applications related to rhinitis and other conditions involving nasal congestion. -
Drug Derivative
MRS 2500 is a potent drug derivative that selectively targets adenosine A3 receptors. This compound exhibits significant effects on cellular signaling pathways, making it valuable for research involving inflammation and cancer biology. MRS 2500 can be utilized in studies aimed at understanding the role of adenosine receptors in various physiological and pathological processes. -
Alkaloid
N-(2-Hydroxy-3-methylbutyl)-adenosine is a natural alkaloid that modulates adenosine receptors. Its biological activity includes influencing various cellular processes such as inflammation and neuroprotection. This compound is utilized in research exploring adenosine signaling pathways and its implications in physiological and pathological conditions. -
Exenatide Impurity
(D-Asp28)-Exenatide is an impurity of Exenatide, which functions as a long-acting glucagon-like peptide-1 (GLP-1) receptor agonist. This compound plays a significant role in the regulation of glucose homeostasis and appetite control, making it relevant for research in diabetes and obesity. The characterization of this impurity is essential for understanding the pharmacological properties and ensuring the quality of Exenatide in therapeutic applications. -
Pressor/Sympathomimetic Agent
Gepefrine is an orally active sympathomimetic agent with pressor properties. It primarily targets adrenergic receptors, enhancing vascular response and improving arterial pressure regulation. Gepefrine is utilized in research to study its effects on orthostatic dysregulation and cardiovascular dynamics. -
Drug Derivative
SKF 83692 is a potent derivative that primarily targets dopamine receptors, specifically D1-like receptors. This compound exhibits notable biological activity in modulating dopaminergic signaling, making it valuable for research in neuropharmacology and the study of dopamine-related disorders. SKF 83692 serves as an important tool for investigating receptor pharmacology and the potential therapeutic effects of dopamine modulation in various neurological conditions. -
Propranolol Analogue
KP-19 is a Propranolol analogue that targets β-adrenergic receptors, influencing cardiac function and stress response. This compound exhibits potential biological activity in modulating cardiovascular mechanisms and offers insights into the treatment of cardiovascular diseases. Its application in research may contribute to understanding therapeutic strategies for managing heart-related conditions. -
Benzofuran
5-EAPB hydrochloride is a benzofuran derivative that acts primarily as a serotonin and dopamine receptor modulator. This compound is known for its psychoactive properties and has been used in neurological research to explore the mechanisms of mood regulation and cognitive function. Its ability to enhance serotonergic transmission makes it a valuable tool for studying various neuropharmacological applications. -
Intermediate
4-Propionamidophenol is an important intermediate in the synthesis of alkanolamine derivatives, primarily targeting β-adrenergic receptors. This compound exhibits significant β-adrenergic blocking activity, making it useful for research into cardiovascular conditions, including heart disease and hypertension. Its utility in synthesizing related compounds enhances its potential for various pharmacological studies. -
Phytocannabinoid
Δ9-Tetrahydrocannabivarinic acid (THCVA) is a phytocannabinoid that acts primarily on cannabinoid receptors, influencing various physiological processes. It exhibits potential anti-inflammatory properties and may play a role in modulating appetite and pain perception. THCVA is of interest in research relating to the therapeutic applications of cannabinoids in treating metabolic disorders and neurological conditions. -
Semaglutide Prodrug
Semaglutide Main Chain (9-37) serves as a peptide starting material for the synthesis of the semaglutide prodrug. This compound is integral in facilitating the development of semaglutide, which is a GLP-1 receptor agonist known for its role in enhancing glucose-dependent insulin secretion and reducing appetite. It is widely applicable in diabetes research and therapeutic development aimed at metabolic disorders. -
Somatostatin Analogue
DOTAMTATE is a somatostatin analogue that selectively targets somatostatin receptors. It exhibits significant potential for the imaging and treatment of somatostatin receptor-positive neuroendocrine tumors, making it a valuable tool for investigative research in oncology and radiopharmaceutical applications. The incorporation of 212Pb into DOTAMTATE enhances its therapeutic efficacy and suitability for targeted radionuclide therapy.
