Biotin-azide (N-(3-Azidopropyl)biotinamide) serves as a versatile click chemical reagent featuring a terminal azide moiety. This compound facilitates the synthesis of biotinylated conjugates through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, Biotin-azide is capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with dibenzocyclooctyne (DBCO) or bicyclo[6.1.0]nonyne (BCN) functional groups. Its applications span various fields, including bioconjugation and visualization studies in chemical biology.
Biotin-azide (N-(3-Azidopropyl)biotinamide) serves as a versatile click chemical reagent featuring a terminal azide moiety. This compound facilitates the synthesis of biotinylated conjugates through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, Biotin-azide is capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with dibenzocyclooctyne (DBCO) or bicyclo[6.1.0]nonyne (BCN) functional groups. Its applications span various fields, including bioconjugation and visualization studies in chemical biology.
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