Catalog No.
Product Name
Application
Product Information
Citations
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Adenosine Analog
4’-C-Methyl-N6-methyladenosine is an adenosine analogue that primarily targets adenosine receptors. This compound exhibits significant biological activity as a vasodilator, promoting smooth muscle relaxation, and has shown potential in inhibiting cancer cell progression. It serves as a valuable tool in research applications focused on vascular biology and cancer therapeutics. -
Purine Nucleoside Analog
N1-Allylpseudouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research and therapeutic applications. Researchers can leverage its properties to explore therapeutic strategies for treating various malignancies. -
Purine Nucleoside Analog
5’-Azido-5’-deoxy-2’-O-(2-methoxyethyl)uridine is a purine nucleoside analog that exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action involve the inhibition of DNA synthesis and the induction of apoptosis. This compound also serves as a click chemistry reagent, featuring an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing alkyne groups or DBCO/BCN moieties. These properties make it a valuable tool for research in chemical biology and medicinal chemistry. -
Purine Nucleoside Analog
2'-O-Hexadecanyl guanosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer effects are primarily attributed to the inhibition of DNA synthesis and the induction of apoptosis. This compound is valuable for research applications focused on cancer biology and therapeutics targeting nucleoside metabolism. -
Nucleotide Derivative
7-Deazaadenosine 5'-phosphate (7-Deaza-AMP) is a nucleotide derivative that serves as a potential substrate or competitive inhibitor for enzymes interacting with 5'-adenylic acid monophosphate. By modulating intracellular signaling pathways, particularly those involving AMP, 7-Deazaadenosine 5'-phosphate can influence various cellular functions. This compound is useful in research applications exploring nucleotide metabolism and signaling events in cellular biology. -
Purine Nucleoside Analog
2-Chloro-N6-methyl-2’-deoxyadenosine is a purine nucleoside analog that demonstrates significant antitumor activity against indolent lymphoid malignancies. This compound exerts its anticancer effects primarily through the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. It serves as a valuable tool in cancer research, particularly in the study of mechanisms underlying cellular proliferation and programmed cell death. -
Purine Nucleoside Analog
5’-O-(4,4-Dimethoxytrityl)-2’-O-methyl inosine is a purine nucleoside analog that inhibits DNA synthesis and promotes apoptosis in cancer cells. It demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. This compound serves as a valuable tool in cancer research, facilitating the study of nucleoside metabolism and therapeutic mechanisms in oncological applications. -
Purine Nucleoside Analog
2',3'-Bis-(O-t-butyldimethylsilyl)uridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is useful in evaluating therapeutic strategies targeting specific malignancies and elucidating the underlying mechanisms of nucleoside metabolism in treated cells. -
Purine Nucleoside Analog
3-O-Benzoyl-1,2:5,6-bis(di-O-isopropylidene)-alpha-D-galactofuranose is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its biological efficacy is primarily mediated through the inhibition of DNA synthesis and the induction of apoptosis. This reagent is valuable for research into cancer therapeutics and the mechanisms of nucleoside analog effects in oncological studies. -
Nucleoside Analog
Rp-ATPαS tetrasodium is a nucleoside analog that serves as a critical substrate in nucleic acid synthesis. This compound is utilized for various biotechnological applications, including the study of RNA synthesis and enzymatic functions in nucleotide metabolism. Its unique properties facilitate research into biochemical pathways and nucleic acid interactions, making it a valuable tool for molecular biology studies. -
Purine Nucleoside Analog
8-Azido-2′-deoxyadenosine is a purine nucleoside analog that exhibits significant antitumor activity. This compound primarily functions by inhibiting DNA synthesis and inducing apoptosis, making it a valuable reagent for research in oncology, particularly in studies targeting indolent lymphoid malignancies. Its unique properties make it a useful tool for investigating cancer cell biology and therapeutic strategies. -
Purine Nucleoside Analog
2-Hydroxy-2'-deoxy-2'-fluoro-beta-D-arabino adenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis in cancerous cells. This compound serves as a valuable reagent for research applications focused on cancer biology and therapeutic interventions in lymphoid tumors. -
Nucleoside Metabolite
2-Hydroxyhepta-2,4-dienedioate is a nucleoside metabolite that plays a significant role in various biological processes. This compound is involved in metabolic pathways relevant to nucleoside metabolism and may serve as a valuable tool for studying nucleic acid synthesis and regulation. Its unique chemical structure enables exploration of its function in cellular activities and potential therapeutic applications in nucleic acid-related research. -
Purine Nucleoside Analog
2',3',5'-Tri-O-benzoyl-2'-beta-C-methyl-6-azauridine is a purine nucleoside analog that exhibits notable antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound can be utilized in studies aimed at understanding the therapeutic potential of nucleoside analogs in oncology. -
Purine Nucleoside Analog
3’-O-Methyl-4-deoxy uridine is a purine nucleoside analogue that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism of action involves the inhibition of DNA synthesis, leading to the induction of apoptosis in cancer cells. This reagent is valuable for research applications focused on cancer biology and therapeutic development. -
Serotonin Product
Formyl-5-hydroxykynurenamine is a metabolite derived from serotonin through the enzymatic activity of indoleamine 2,3-dioxygenase 1 (IDO1). This compound plays a crucial role in the catabolism of serotonin, influencing various biological pathways. It is utilized in research to study serotonin metabolism and its implications in neurological disorders and immune responses. -
Purine Nucleoside Analog
1-(3-β-Azido-2,3-dideoxy-5-O-trityl-D-threopenta-furanosyl)thymine is a purine nucleoside analog that exhibits significant antitumor activity. This compound primarily functions by inhibiting DNA synthesis and inducing apoptosis, making it valuable in the treatment of indolent lymphoid malignancies. Its unique structural properties enable researchers to explore therapeutic applications in cancer biology and nucleic acid metabolism. -
Linoleic Acid Metabolite
9,10-Dihydroxy-12,13-epoxyoctadecanoate is a linoleic acid metabolite that plays a crucial role in fatty acid metabolism. This compound exhibits notable biological activity, influencing various biochemical pathways associated with lipid metabolism. Its applications in research include studying inflammation, cellular signaling, and potential roles in metabolic disorders. -
Cytosolic Thymidine Kinase/Mitochondrial Enzyme Inhibitor
Ap5dT is an inhibitor of cytosolic thymidine kinase and mitochondrial enzymes, exhibiting inhibition constants (Kis) of 0.12 μM and 0.50 μM, respectively. This compound is relevant for research on acute myelocytic leukemia, facilitating investigations into thymidine metabolism and its implications in cancer biology. Its selective inhibition properties make Ap5dT a valuable tool for studying metabolic pathways involved in cellular proliferation. -
Purine Nucleoside Analog
7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy guanosine is a purine nucleoside analog known for its broad antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound functions as a click chemistry reagent featuring an alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules. This versatility makes it suitable for various applications in chemical biology and drug discovery. -
Purine Nucleoside Analog
6-Methoxy purine-9-beta-D-(3’-deoxy-3’-fluoro)riboside is a purine nucleoside analogue that primarily targets DNA synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as the inhibition of DNA replication and the induction of apoptosis. Its unique structure allows for diverse applications in cancer research and therapeutic development. -
Adenosine Analog
N6-Isopentenyl-2’-C-methyladenosine is an adenosine analog that primarily acts as a vasodilator by influencing adenosine receptors. This compound has demonstrated potential in inhibiting cancer progression, making it valuable for research in oncology and cardiovascular studies. Its unique structure allows for diverse applications in studying nucleotide metabolism and therapeutic interventions targeting adenosine signaling pathways. -
Nucleoside Metabolite
7,8-Dihydro-7,8-dihydroxykynurenic acid is a nucleoside metabolite that plays a role in the modulation of neurotransmitter systems. This compound exhibits neuroprotective properties and is involved in the kynurenine pathway, which has implications in neurological disorders. It is utilized in research applications focused on neurobiology and neuropharmacology, particularly in studies related to neurodegeneration and psychiatric conditions. -
Nucleoside Analogue
OGT-719 is a potent, orally active nucleoside analogue targeting the asialoglycoprotein receptor (ASGP-R). This compound demonstrates significant inhibition of metastatic colorectal tumor growth in the liver of nude mice. OGT-719 is suitable for research applications focused on primary hepatocellular carcinoma and colorectal liver metastases. -
Purine Nucleoside Analog
4’-Azido-3’-O-benzoyl-5’-O-(m-chlorobenzoyl)-2’-deoxy-2’-fluoro-beta-D-arabinouridine functions as a purine nucleoside analog, demonstrating significant antitumor activity against indolent lymphoid malignancies. Its anticancer mechanisms include the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a versatile click chemistry reagent, featuring an azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups. This functionality makes it valuable in bioconjugation studies and various chemical biology applications. -
Nucleoside Antimetabolite/Analog
(±)-Lobucavir is a nucleoside antimetabolite/analog known for its carcinogenic activity. Research indicates that chronic administration of (±)-Lobucavir in murine models leads to tumor formation with a similar spectrum to that observed with other nucleoside analogs such as zidovudine or ganciclovir. This compound serves as a valuable tool for studying the mechanisms of nucleoside analog-induced carcinogenesis and their effects in oncological research. -
Purine Nucleoside Analog
6-Chloro-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-9H-purine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer properties are primarily attributed to the inhibition of DNA synthesis and the induction of apoptosis in malignant cells. This compound serves as a valuable tool for research applications focused on oncology and the development of novel therapeutic strategies. -
Purine Nucleoside Analog
3',5'-Di-O-acetyl-2'-deoxy-5,N3-dimethyluridine is a purine nucleoside analog that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms primarily involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound can be utilized in studies aimed at understanding cellular responses to nucleoside analogs and their potential therapeutic effects. -
Purine Nucleoside Analog
5-Amino-2'-deoxyuridine monohydrochloride is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for research in cancer biology and therapeutic development. This compound is applicable in studies focused on nucleic acid metabolism and the exploration of novel cancer treatments. -
Uridine Analog
5’-O-DMT-2’-deoxy-2’-fluoro-β-D-arabinouridine is a uridine analog that targets various biological pathways associated with nucleoside metabolism. This compound exhibits potential antiepileptic effects, making it valuable for research in anticonvulsant and anxiolytic activities. Additionally, its unique structure facilitates the exploration of novel antihypertensive agents, contributing to advancements in therapeutic development. -
Uridine Analog
3′,5′-Di-O-acetyl-2′-deoxy-2′-fluorouridine is a uridine analog that serves as a valuable tool for investigating antiepileptic mechanisms. This compound has been shown to possess anticonvulsant and anxiolytic properties, making it useful in the exploration of new therapeutic pathways. Additionally, its structural modifications contribute to the development of novel antihypertensive agents, facilitating research in cardiovascular pharmacology. -
Nucleoside
L-5-Methyluridine is a nucleoside with significant biological relevance, serving as an endogenous methylated form prevalent in human fluids. Its unique structure contributes to various cellular processes, including modulation of RNA stability and translation. This compound is utilized in research exploring RNA function and methylation patterns, making it a valuable reagent for studies related to gene expression and regulation. -
Purine Nucleoside Analog
2’-Azido-2’-deoxy-5-methyl cytidine is a purine nucleoside analog with significant antitumor activity, particularly in targeting indolent lymphoid malignancies. Its anticancer effects are primarily mediated through the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a versatile click chemistry reagent, featuring an azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules that possess DBCO or BCN groups. -
Purine Nucleoside Analog
3’-Deoxy-3’-α-C-methyl-5-fluorouridine is a purine nucleoside analog that primarily targets DNA synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by disrupting nucleotide incorporation into nucleic acids. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research applications. -
Anticancer Agent
Fosfluridine Tidoxil is an oral-active anticancer agent that utilizes a specific carrier molecule linked by a phosphate group to 5-Fluorouridine (5-FUrd), a metabolite of 5-Fluorouracil (5-FU). This compound demonstrates significant cytotoxic activity against various cancer cell lines, making it a valuable tool in cancer research. Fosfluridine Tidoxil is primarily applied in studies focusing on targeted cancer therapies and the exploration of drug metabolism and efficacy. -
Nucleoside Analogue
Methyl 2-deoxy-3,5-di-O-benzoyl-2-fluoro-4-thio-D-arabinopentofuranoside is a ribofuranose nucleoside analogue designed to target nucleoside-dependent pathways. This compound exhibits potential antiviral activity, particularly against certain RNA viruses, and is valuable for research in nucleoside metabolism and therapeutic development. Its structural modifications may enhance stability and bioavailability, making it a useful tool for studying nucleoside interactions and biochemical mechanisms. -
Purine Nucleoside Analog
2’-β-C-Methyl-5-methyluridine is a purine nucleoside analog with significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. This compound is utilized in research focused on cancer biology and the evaluation of therapeutic strategies targeting nucleoside metabolism. -
Purine Nucleoside Analog
2'-Deoxy-N2,N2-dimethylguanosine is a purine nucleoside analog that exhibits notable antitumor activity, particularly against indolent lymphoid malignancies. Its biological action primarily involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. Researchers can utilize this compound in studies focused on cancer biology and the development of therapeutic strategies targeting nucleoside metabolism. -
Purine Nucleoside Analog
2'-Deoxy-N4,N4-dimethylcytidine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism of action involves the inhibition of DNA synthesis, which promotes apoptosis in cancer cells. This compound is valuable for research applications focused on cancer biology and the development of novel therapeutic strategies. -
Purine Nucleoside Analog
2’-Deoxy-O6-[2-(4-nitrophenylethyl)]guanosine is a purine nucleoside analog that exhibits potent antitumor activity. This compound primarily targets and inhibits DNA synthesis, leading to the induction of apoptosis in cancer cells. It is particularly useful for researching indolent lymphoid malignancies, providing insights into anticancer mechanisms and therapeutic strategies. -
Cytidine Analog
5-Formyl-2’-O-methylcytidine is a cytidine nucleoside analog that acts as an inhibitor of DNA methyltransferases. This compound exhibits potential anti-metabolic and anti-tumor activity, making it a valuable tool in cancer research and epigenetic studies. Its unique structure allows for the investigation of nucleoside metabolism and modifications within nucleic acid processes. -
Steroid Metabolite
17-Deoxycortolone is a steroid metabolite that serves as a crucial intermediate in steroidogenesis. It is involved in the biosynthesis of corticosteroids and plays a role in various biological processes. This reagent is primarily utilized in biochemical research focusing on steroid metabolism and endocrine function. -
Guanylate Kinases Inhibitor
Guanosine 3',5'-bisdiphosphate (ppGpp) acts as a specific inhibitor of guanylate kinases, affecting GTP biosynthesis in chloroplasts. By inhibiting plastid and mitochondrial guanylate kinase activity, ppGpp is crucial for understanding metabolic regulation and signaling processes in plant systems. This reagent is valuable for research applications involving nucleotide metabolism and signaling pathways. -
Cytidine Analog
3’-O-(2-Methoxyethyl)cytidine is a cytidine analog that functions primarily as an inhibitor of DNA methyltransferases. This compound exhibits significant potential in anti-metabolic and anti-tumor research applications, providing a valuable tool for studying epigenetic regulation and cancer biology. Its ability to interfere with DNA methylation processes makes it an important reagent for investigating cellular pathways associated with gene regulation and tumor progression. -
Phosphonic Acid
2-Methylaminoethylphosphonic acid is a naturally occurring phosphonic acid that acts as a key metabolite in various marine organisms. It has been implicated in neurotransmitter regulation and cellular signaling pathways. This compound serves as a valuable research tool in studying biological processes related to phosphonates, neurobiology, and marine biochemistry. -
Purine Nucleoside Analog
2’-Amino-2’-deoxy-β-D-arabinouridine is a purine nucleoside analog known for its antitumor activity against indolent lymphoid malignancies. This compound exerts its biological effects primarily through the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. It is particularly relevant in studies aimed at understanding and developing treatments for specific types of hematological cancers. -
Nucleoside Metabolite
2,3-Dihydroxyindole is a nucleoside metabolite that plays a crucial role in various biochemical processes. This compound is known for its potential involvement in melanin biosynthesis and exhibits antioxidant properties. Research applications include studies on pigment formation and its implications in skin biology and related disorders. -
Purine Nucleoside Analog
N6-Methyl-4’-thio-adenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for research in cancer biology and therapeutic development. This reagent is suitable for studies investigating the molecular pathways of cell proliferation and death in malignancies. -
Purine Nucleoside Analog
2’-O-Methyl-2-thiouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is suitable for studies aimed at understanding the molecular pathways of tumor progression and therapeutic responses in malignancies. -
Purine Nucleoside Analog
Purine-9-b-D-(3’,5’-di-O-benzoyl-2’-deoxy-2’-fluoro)arabinoriboside is a purine nucleoside analog that exhibits potent antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is suitable for studies focused on understanding the therapeutic potential of nucleoside analogs in oncology.
