Fig. 1 · Structure
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DDL-218
SirT1 Enhancer
DDL-218 is a potent enhancer of the SirT1 protein, specifically targeting its activity. It has demonstrated efficacy in augmenting SirT1 function in ApoE4-expressing neurons and in murine models of Alzheimer's disease. DDL-218 serves as a valuable tool for investigating SirT1-related pathways and their implications in neurodegenerative disorders, particularly Alzheimer's disease.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2767324-34-3 |
| Applications | SirT1 Enhancer |
| Formula | C12H18N2O2 |
| Molecular Weight | 222.28 |
| SMILES | N[C@@H](C)C(OC(C)(C)CC1=CC=NC=C1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.