Fig. 1 · Structure
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YK-3-237
SIRT1 Activator
YK-3-237 is a selective activator of SIRT1, targeting mutant p53 proteins. This compound has demonstrated the ability to inhibit the proliferation of triple-negative breast cancer cells, making it a valuable tool for research into cancer biology and potential therapeutic strategies. It may provide insights into the role of SIRT1 in tumor progression and cellular metabolism.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 1215281-19-8 |
| Applications | SIRT1 Activator |
| Formula | C19H21BO7 |
| Molecular Weight | 372.18 |
| SMILES | COC1=C(C=C(C=C1OC)C(/C=C/C2=CC(B(O)O)=C(C=C2)OC)=O)OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.