Catalog No.
Product Name
Application
Product Information
Citations
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BLC6/BLC6B Degrader
ALV-05-151-02 is a degrader of BCL6 and BCL6B, effectively reducing endogenous BCL6 levels in SuDHL4 cells and BCL6B levels in KYO1 cells, which exhibit high expression of these targets. This compound serves as a valuable tool for researching hematological malignancies by facilitating the study of the role of BCL6 and BCL6B in various malignancies. -
Anti-inflammatory Agent
Metiazinic acid is an anti-inflammatory agent that functions through the inhibition of key inflammatory pathways. It demonstrates significant biological activity in reducing inflammation and is valuable for research applications aimed at understanding inflammatory processes and developing therapeutic strategies for inflammatory diseases. -
Anti-inflammatory Agent
Fanetizole is an anti-inflammatory agent that targets specific pathways involved in inflammatory responses. It has demonstrated notable efficacy in reducing inflammation, making it a valuable compound for the study of inflammatory diseases. Researchers can utilize Fanetizole to explore mechanisms of action and potential therapeutic applications in various inflammatory conditions. -
Hapten
AdBeSA is a hapten that modulates peptide binding to MHC class II molecules. This structural analog can alter immune responses by impacting antigen presentation. Its primary application is in the study of T-cell activation and the design of peptide-based vaccines. AdBeSA serves as an important tool for researchers investigating immune system interactions and therapeutic strategies targeting autoimmune diseases. -
Anti-inflammatory Agent
1-O-Tigloyl-1-O-debenzoylohchinal is an orally active limonoid-type triterpenoid with anti-inflammatory properties. It demonstrates significant inhibition of acetic acid-induced increases in vascular permeability, λ-Carrageenan-induced paw edema, and acetic acid-induced writhing in murine models, indicating its potential as a peripheral analgesic agent. Notably, it does not exert significant effects in central pain models, highlighting its peripheral action. This compound is suitable for research focused on acute and chronic inflammatory conditions and related gastrointestinal disorders. -
Anti-inflammatory/Antipyretic/Analgesic Agent
Pipebuzone is an anti-inflammatory, antipyretic, and analgesic agent that targets multiple pathways involved in the inflammatory response. It exhibits significant biological activity in reducing inflammation and alleviating pain associated with rheumatic diseases. Researchers commonly utilize Pipebuzone in studies aimed at understanding the mechanisms of inflammation and exploring potential therapeutic interventions for inflammatory disorders. -
Anti-inflammatory agent
Sanggenon B is an anti-inflammatory agent that exhibits inhibitory effects on nitric oxide (NO) production in LPS-stimulated RAW264.7 macrophage cells. This compound, extracted from mulberry trees, serves as a valuable tool in research applications focused on understanding and mitigating inflammatory processes. Its biological activity positions it as a potential candidate for further exploration in therapeutic contexts related to inflammation. -
CD36 Ligand
EP 80317 is a selective ligand for CD36. This compound exhibits cardioprotective effects against damage and dysfunction caused by myocardial ischemia and reperfusion, while also temporarily reducing peripheral lipolysis. EP 80317 is valuable in the investigation of cardiovascular disease mechanisms and potential therapeutic interventions. -
Anti-Inflammatory Agent
Cucurbitadienol is a natural compound primarily known for its anti-inflammatory properties. Isolated from the seeds of Trichosanthes kirilowii, this tetracyclic terpene has been shown to modulate inflammatory pathways. Its biological activity makes it a valuable tool in research focused on understanding and developing treatments for inflammatory diseases. -
MHC class II epitope antigen
M30 peptide is an MHC class II epitope antigen that plays a crucial role in initiating T cell responses. This peptide is particularly valuable in cancer nanovaccine research, facilitating the development of targeted immunotherapies. By enhancing antigen presentation, M30 peptide supports investigations into adaptive immune responses against tumors. -
Anti-inflammatory Agent
Alpinenone is a sesquiterpene compound with anti-inflammatory properties. It acts by inhibiting the overproduction of nitric oxide (NO), thereby reducing inflammation. Alpinenone is suitable for research applications focused on inflammation-related diseases, as well as gastrointestinal and urinary system disorders. -
MHC class I epitope antigen
M27 peptide is an MHC class I epitope antigen that plays a crucial role in immune response modulation. Its primary application lies in cancer nanovaccine research, facilitating the development of targeted immunotherapies. By presenting specific antigenic sequences, M27 peptide aids in the identification and activation of T lymphocytes, contributing to enhanced anti-tumor immune responses. -
Anti-Inflammatory Agent
Prinomide triethanolamine is an orally available nonsteroidal anti-inflammatory agent targeting pathways involved in inflammation. It exhibits significant anti-inflammatory properties and is utilized in research focused on inflammatory diseases, including rheumatoid arthritis. This reagent provides valuable insights into the mechanisms of inflammation and the potential therapeutic effects of anti-inflammatory compounds. -
Anti-Inflammatory Agent
Anti-inflammatory agent 36 is a potent anti-inflammatory compound that selectively inhibits lipopolysaccharide (LPS)-induced macrophage activation. This mechanism aids in modulating inflammatory responses, making it a valuable tool for studying inflammatory pathways and potential therapeutic interventions. Its application is pivotal in researching conditions characterized by excessive inflammation, contributing to a better understanding of inflammatory diseases. -
Anti-inflammatory Agent
EVT‑401 is an anti-inflammatory agent that modulates immune responses by inhibiting key inflammatory pathways. It demonstrates significant pharmacological effects in vivo and is valuable for studying various inflammatory conditions. EVT‑401 is a potent tool for research focused on understanding the mechanisms of inflammation and potential therapeutic interventions. -
Anti-inflammatory/antioxidant
S-Carboxymethyl-L-cysteine L-lysine monohydrate is a mucosal active compound that demonstrates notable anti-inflammatory and antioxidant properties. This reagent is primarily utilized in research related to chronic obstructive pulmonary disease (COPD), where it may help in elucidating the underlying mechanisms of inflammation and oxidative stress. Its unique profile makes it valuable for studies aimed at developing therapeutic strategies for respiratory conditions. -
Anti-inflammatory Agent
Zidometacin is a nonsteroidal anti-inflammatory agent that primarily targets prostaglandin synthesis, effectively reducing inflammation with a diminished risk of gastrointestinal toxicity. It exhibits notable antinociceptive and antipyretic properties, demonstrating low ulcerogenic potential in rat models. Zidometacin is applicable in research focused on analgesia and osteoarthritis, contributing valuable insights into pain management and inflammatory processes. -
Anti-inflammatory Agent
PH-46A is an indane dimer that operates as an anti-inflammatory agent. It has demonstrated the ability to reduce histological damage and lower serum amyloid A (SAA) levels in murine models of colitis. This compound is valuable for research applications focused on inflammatory diseases and therapeutic intervention strategies. -
Anti-inflammatory Agent
5,7,5′-Trihydroxy-3′,4′-dimethoxyflavonol-3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside functions as an anti-inflammatory agent and belongs to the flavonol glycoside class. This compound, isolated from Ginkgo biloba leaves, demonstrates significant antioxidative and cardioprotective properties. Its application extends to investigating mechanisms underlying inflammation and cardiac injury, making it a valuable reagent for biochemical and pharmacological research. -
Anti-inflammatory Agent
Chinoin 127 is a non-anesthetic analgesic agent that exhibits significant anti-inflammatory properties. Demonstrated to provide potent analgesic effects in various models, including the hot plate test, Randall-Selitto test, and torsion test, Chinoin 127 is valuable for research applications aimed at understanding pain mechanisms and developing therapies for inflammatory conditions. -
Anti-inflammatory Agent
Diacetyl boldine is an anti-inflammatory agent known for its soothing and moisturizing properties. This compound is investigated for its potential effects on skin disorders, particularly melasma and lentigo senilis. Its biological activity makes it a valuable reagent for research focused on dermatological applications and skin health. -
BLC6/BLC6B Degrader
ALV-05-077-01 is a selective degrader of BCL6 and BCL6B proteins. It effectively reduces endogenous BCL6 levels in SuDHL4 cells and BCL6B levels in KYO1 cells, both of which exhibit high expression of these proteins. This compound is useful for investigating the role of BCL6 and BCL6B in hematological malignancies and provides insight into potential therapeutic strategies targeting these proteins. -
Anti-Inflammatory Agent
Prinomide tromethamine is an orally available nonsteroidal anti-inflammatory agent that targets inflammatory pathways. It exhibits significant biological activity by reducing inflammation and alleviating symptoms associated with conditions such as rheumatoid arthritis. This compound is valuable for research focused on understanding inflammatory mechanisms and developing therapeutic strategies for related diseases. -
Anti-Inflammatory Agent
Polyporoid C is an ergostane-type ecdysteroid with strong anti-inflammatory properties. It has been demonstrated to reduce inflammation in vivo, making it a valuable tool for investigating inflammatory pathways. This compound is suitable for research applications focused on inflammation modulation and therapeutic mechanisms. -
Antiinflammatory Agent
Etofesalamide is a nonsteroidal anti-inflammatory agent that targets inflammatory pathways to modulate immune responses. It exhibits significant biological activity through its major phase II metabolites, including glucoside and riboside conjugates, such as etofesalamide-2-glucuronide in filamentous fungi. This compound is applicable in research related to allergic and autoimmune skin disorders, including acne, psoriasis, and contact dermatitis. -
Anti-inflammatory Agent
Zizyvoside I is a bioactive compound derived from Dioscorea septemloba, known for its anti-inflammatory properties. This compound has demonstrated the ability to modulate inflammatory responses, making it a valuable tool in research focused on inflammatory diseases. Zizyvoside I can be utilized in studies investigating the underlying mechanisms of inflammation and the development of therapeutic strategies. -
Anti-inflammatory Agent
DD-3305 is an anti-inflammatory agent that significantly reduces both acute and chronic inflammation. In models of carrageenan-induced inflammation in rats, DD-3305 demonstrated comparable efficacy to indomethacin, effectively abating inflammatory responses and allergy-related symptoms. This compound is a valuable tool for research applications focused on inflammation pathways and potential therapeutic interventions. -
Multiple Sclerosis Immune Modulator
Glatiramer acetate is a synthetic analogue of myelin basic protein that functions primarily as an immune modulator for the treatment of multiple sclerosis. Its mechanism involves inhibiting experimental autoimmune encephalomyelitis (EAE) by competing with myelin antigens for binding to MHC molecules, which subsequently modulates T cell response. Additionally, glatiramer acetate promotes the induction of T helper 2 (Th2) cells, which migrate to the central nervous system and facilitate localized immunosuppression. This compound serves as a valuable tool for research into autoimmune disorders and therapeutics for multiple sclerosis. -
Anti-inflammatory agent
SerBut is a serine-conjugated butyrate prodrug designed to exert anti-inflammatory effects. It demonstrates potential therapeutic activity in modulating inflammation, making it suitable for research applications targeting inflammatory pathways and related diseases. Its oral bioactivity enhances its utility in in vivo studies. -
Nonsteroidal Anti-inflammatory Drug
Azapropazone is a nonsteroidal anti-inflammatory drug (NSAID) primarily targeting the inhibition of cyclooxygenase enzymes. This compound exhibits significant anti-inflammatory and analgesic properties, making it valuable in the study of rheumatoid arthritis and related inflammatory disorders. Researchers can utilize Azapropazone to investigate its effects on pain management and the underlying mechanisms of inflammatory conditions. -
Anti-inflammatory Agent
Fenclozic acid is an orally active anti-inflammatory agent that exerts its effects by inhibiting prostaglandin synthesis. It demonstrates significant analgesic and antipyretic properties, making it useful in the study of pain and fever management. Researchers commonly utilize fenclozic acid to explore pathways underlying inflammation and to develop therapeutic strategies for related conditions. -
Hapten
J10-1 is a hapten that enhances peptide exchange among various DR alleles, including DR1, DR2, and DR4 (specifically DRB1*0401). This compound facilitates the binding of peptides to MHC class II molecules, making it a valuable tool for investigating immune regulation and responses. Its utility in research applications can aid in the understanding of T cell activation and autoimmune diseases. -
Anti-inflammatory Substance
Kebuzone is a non-steroidal anti-inflammatory compound that targets inflammatory pathways. It exhibits significant anti-inflammatory activity and may be useful in research related to inflammatory diseases, including thrombophlebitis and rheumatoid arthritis. This reagent provides a valuable tool for studying mechanisms of inflammation and exploring potential therapeutic strategies. -
Non-steroidal Anti-inflammatory Agent
Difenpiramide is a non-steroidal anti-inflammatory agent that exhibits pronounced anti-inflammatory, analgesic, antipyretic, and uricosuric properties. This compound also demonstrates platelet anti-aggregation activity, making it valuable for research applications in inflammation, pain management, and cardiovascular studies. Its multifaceted biological activities contribute to its potential use in various therapeutic contexts. -
Anti-inflammatory Agent
Furobufen is an anti-inflammatory agent that exerts antiarthritic and antipyretic effects, providing significant relief in conditions characterized by inflammation. Its analgesic properties are particularly pronounced in inflamed tissues, making it a valuable compound for research applications focused on pain management and inflammatory diseases. This compound can be utilized in exploring therapeutic strategies for various inflammatory conditions. -
Antiinflammatory Agent
D228 is an orally active anti-inflammatory agent that targets T and B lymphocytes. It effectively reduces ConA-induced T cell proliferation with an IC50 of 42.85 μM and LPS-induced B cell proliferation with an IC50 of 3.15 μM. D228 demonstrates efficacy in the treatment of inflammatory bowel disease (IBD) by alleviating inflammation in the DSS-induced IBD model, primarily through the downregulation of the MyD88/TRAF6/p38 signaling pathway. -
FAP Modulator
SID 125240931 is a modulator of fluorogen activating proteins (FAPs), primarily targeting the interaction between fluorogens and FAP. This compound is designed to disrupt binding affinity, providing insights into FAP-mediated processes. It has potential applications in cellular imaging and monitoring protein interactions, making it a valuable tool for researchers in cell biology and molecular imaging studies. -
Anti-Inflammatory Agent
Anti-inflammatory agent 32 (compound C3) functions as an anti-inflammatory agent, exhibiting notable antioxidative properties. This compound is ideal for research focused on anti-inflammatory mechanisms and skin care product development, contributing valuable insights into inflammatory pathways and therapeutic interventions. -
Anti-inflammatory Agent
Nicotredole is an orally active anti-inflammatory agent that primarily targets inflammatory pathways. It demonstrates significant anti-inflammatory and analgesic effects, exhibiting potency comparable to that of Phenylbutazone while presenting only minimal ulcerogenic activity. Nicotredole is suitable for research applications focused on inflammation and pain management studies. -
Anti-inflammatory Agent
Tetridamine is a non-steroidal anti-inflammatory agent that primarily targets inflammatory pathways. It has been demonstrated to significantly reduce paw swelling and alleviate pain sensitivity in various models of inflammation. This compound is valuable for research into inflammation-related conditions and the development of novel anti-inflammatory therapies. -
Anti-inflammatory Agent
Cedrol methyl ether is an anti-inflammatory agent derived from ginger. It exhibits significant anti-inflammatory activity, making it a valuable compound for research applications related to hyperhidrosis and abnormal vaginal discharge. Its potential uses in studying inflammatory conditions highlight its importance in biochemical and therapeutic investigations. -
Anti-Inflammatory Agent
Mosedipimod is a monoacetyldiaglyceride that functions as a Toll-Like Receptor (TLR) signaling inhibitor. It exhibits significant anti-inflammatory activity by reducing myeloperoxidase expression in lung tissue, thereby attenuating airway inflammation. This compound is primarily utilized in research related to chronic obstructive pulmonary disease (COPD), contributing to the understanding of inflammatory pathways and potential therapeutic interventions. -
Anti-inflammatory Analgesic
Isamfazone is an anti-inflammatory analgesic that acts primarily by inhibiting the production of pro-inflammatory mediators. It exhibits significant efficacy in reducing pain and inflammation, making it valuable for investigations into pain management and inflammatory diseases. This compound is utilized in preclinical studies to explore its therapeutic potential in various conditions associated with inflammation. -
Anti-inflammatory Drug
Rivasterat is a cholesterol-derived steroid that exhibits potent anti-inflammatory activity. It functions by modulating inflammatory pathways, making it a valuable tool in research focused on inflammation-related diseases. Its potential applications include studying the role of inflammation in chronic conditions and evaluating therapeutic strategies for inflammatory disorders. -
Anti-Inflammatory Agent
Proquazone is a unique non-steroidal anti-inflammatory agent (NSAID) that lacks a free acid group in its chemical structure. This compound exhibits significant anti-inflammatory, analgesic, and antipyretic activities, making it suitable for various therapeutic applications. Notably, Proquazone has the potential to inhibit or halt the progression of bone erosions, positioning it as a valuable tool in inflammatory disease research.
