1-O-Tigloyl-1-O-debenzoylohchinal is an orally active limonoid-type triterpenoid with anti-inflammatory properties. It demonstrates significant inhibition of acetic acid-induced increases in vascular permeability, λ-Carrageenan-induced paw edema, and acetic acid-induced writhing in murine models, indicating its potential as a peripheral analgesic agent. Notably, it does not exert significant effects in central pain models, highlighting its peripheral action. This compound is suitable for research focused on acute and chronic inflammatory conditions and related gastrointestinal disorders.
1-O-Tigloyl-1-O-debenzoylohchinal is an orally active limonoid-type triterpenoid with anti-inflammatory properties. It demonstrates significant inhibition of acetic acid-induced increases in vascular permeability, λ-Carrageenan-induced paw edema, and acetic acid-induced writhing in murine models, indicating its potential as a peripheral analgesic agent. Notably, it does not exert significant effects in central pain models, highlighting its peripheral action. This compound is suitable for research focused on acute and chronic inflammatory conditions and related gastrointestinal disorders.
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