D228 is an orally active anti-inflammatory agent that targets T and B lymphocytes. It effectively reduces ConA-induced T cell proliferation with an IC50 of 42.85 μM and LPS-induced B cell proliferation with an IC50 of 3.15 μM. D228 demonstrates efficacy in the treatment of inflammatory bowel disease (IBD) by alleviating inflammation in the DSS-induced IBD model, primarily through the downregulation of the MyD88/TRAF6/p38 signaling pathway.
D228 is an orally active anti-inflammatory agent that targets T and B lymphocytes. It effectively reduces ConA-induced T cell proliferation with an IC50 of 42.85 μM and LPS-induced B cell proliferation with an IC50 of 3.15 μM. D228 demonstrates efficacy in the treatment of inflammatory bowel disease (IBD) by alleviating inflammation in the DSS-induced IBD model, primarily through the downregulation of the MyD88/TRAF6/p38 signaling pathway.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
