ALV-05-077-01 is a selective degrader of BCL6 and BCL6B proteins. It effectively reduces endogenous BCL6 levels in SuDHL4 cells and BCL6B levels in KYO1 cells, both of which exhibit high expression of these proteins. This compound is useful for investigating the role of BCL6 and BCL6B in hematological malignancies and provides insight into potential therapeutic strategies targeting these proteins.
ALV-05-077-01 is a selective degrader of BCL6 and BCL6B proteins. It effectively reduces endogenous BCL6 levels in SuDHL4 cells and BCL6B levels in KYO1 cells, both of which exhibit high expression of these proteins. This compound is useful for investigating the role of BCL6 and BCL6B in hematological malignancies and provides insight into potential therapeutic strategies targeting these proteins.
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