ALV-05-151-02

Catalog No.: B19728
BLC6/BLC6B Degrader
ALV-05-151-02 is a degrader of BCL6 and BCL6B, effectively reducing endogenous BCL6 levels in SuDHL4 cells and BCL6B levels in KYO1 cells, which exhibit high expression of these targets. This compound serves as a valuable tool for researching hematological malignancies by facilitating the study of the role of BCL6 and BCL6B in various malignancies.
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Size Stock
5mg
10mg
50mg
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Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionALV-05-151-02 is a degrader of BCL6 and BCL6B, effectively reducing endogenous BCL6 levels in SuDHL4 cells and BCL6B levels in KYO1 cells, which exhibit high expression of these targets. This compound serves as a valuable tool for researching hematological malignancies by facilitating the study of the role of BCL6 and BCL6B in various malignancies.
Product Information
Catalog NumB19728
FormulaC27H28F3N5O4
Molecular Weight543.54
CAS Number2744249-11-2
SMILESCN(C)C(CC(NC1=CC=CC(C(F)(F)F)=C1)=O)C2=CC(NC3=CCN(C4C(NC(CC4)=O)=O)C3=O)=CC=C2
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