Aegeline is a natural alkaloid that targets fungal pathways by mimicking the yeast SNARE protein Sec22p to inhibit α-synuclein and Bax toxicity in yeast models. This compound effectively restores growth in yeast cells impaired by these toxic proteins. Additionally, Aegeline exhibits antioxidant properties, making it a valuable reagent for studying cellular stress responses and neurodegenerative mechanisms in fungal systems.
Aegeline is a natural alkaloid that targets fungal pathways by mimicking the yeast SNARE protein Sec22p to inhibit α-synuclein and Bax toxicity in yeast models. This compound effectively restores growth in yeast cells impaired by these toxic proteins. Additionally, Aegeline exhibits antioxidant properties, making it a valuable reagent for studying cellular stress responses and neurodegenerative mechanisms in fungal systems.
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