Catalog No.
Product Name
Application
Product Information
Citations
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Antitumor Agent
PD 113270 is an antitumor agent that functions primarily through the inhibition of specific cellular pathways. This compound has demonstrated notable inhibitory effects on yeast, indicating its potential use in studying antifungal mechanisms and tumor cell proliferation. PD 113270 is of particular interest for research applications in cancer biology and pharmacology, aiding in the exploration of new therapeutic strategies. -
Antimicrobial Agent
Quadrilineatin is an antimicrobial agent that exhibits significant antifungal and antibacterial activity. It disrupts microbial cell function, making it effective against a broad spectrum of pathogens. This reagent is applicable in research focused on infectious diseases and the development of antimicrobial therapies. -
Antifungal Agent
Antifungal Agent 134 primarily targets fungal pathogens by disrupting cellular membranes and mitochondrial function, resulting in substantial reactive oxygen species (ROS) accumulation. It exhibits potent antifungal activity with EC50 values of 3.24 μg/mL against Botrytis cinerea and varying efficacy against other fungi, including Alternaria and Fusarium species. In addition to its antifungal properties, Antifungal Agent 134 also demonstrates significant herbicidal activity against common field weeds such as Amaranthus retroflexus and Abutilon theophrasti. This compound is suitable for research focused on crop disease management and weed control strategies. -
Antibiotic
Malonylniphimycin is a macrolide antibiotic that targets Gram-positive bacteria, fungi, and yeasts. Isolated from Streptomyces strain hygroscopicus B-7, it demonstrates potent antibacterial activity that makes it a valuable tool for research in antimicrobial resistance and the development of new therapeutic strategies. Its unique structural features and resistance profile provide insights into the mechanisms of action and efficacy against various pathogens. -
Antifungal Agent
Bullatenone is a volatile bioactive compound sourced from Lophomyrtus bullata, primarily functioning as an antifungal agent. It exhibits significant inhibitory effects against fungal pathogens, including Candida albicans and Cladosporium resinae. Due to its multifaceted biological activities, Bullatenone is valuable in researching inflammatory conditions and infectious diseases. -
Antibiotic
Nanaomycin B is an antibiotic that exerts its activity against Gram-positive bacteria, mycobacteria, mycoplasma, and fungi. This compound is utilized in biological research for its potent antimicrobial properties and its ability to inhibit the growth of various microorganisms. Nanaomycin B serves as a valuable tool in studies involving antibiotic resistance and microbial pathogenesis. -
Antibiotic
Ezomycin D2 is an antifungal antibiotic that targets phytopathogens. It demonstrates significant activity against Sclerotinia sclerotiorum and Botrytis, offering effective control against these fungi as well as Candidiasis in crop settings. This compound is valuable for researchers studying agricultural disease management and developing sustainable solutions for crop protection. -
PXR Agonist
Tolindate is a potent PXR agonist, exhibiting an EC50 value of 8.3 μM. This compound demonstrates significant antifungal activity, making it a valuable tool for research in pharmacology and toxicology. Its ability to modulate the pregnane X receptor (PXR) may provide insights into drug metabolism and interactions with xenobiotics. -
Insect toxin
3-GlcA-28-AraRhaxyl-medicagenate is an insect toxin classified within the saponin family. This compound demonstrates notable antifungal properties and has been shown to induce mortality in rice weevils at concentrations as low as 0.1 mg/mL. It serves as a valuable tool for research into insecticidal agents and pest management strategies. -
Anthraquinone Derivative
Neobulgarone E is an anthraquinone derivative isolated from Neobulgaria pura HA A07-97, an ascomycete fungus. This compound effectively inhibits the formation of appressoria in Magnaporthe grisea, making it a valuable tool for research on fungal development and pathogenesis. Notably, Neobulgarone E exhibits minimal cytotoxicity and lacks antifungal, antibacterial, or phytotoxic effects, highlighting its specificity in targeting fungal processes without adversely affecting other biological systems. -
Antibiotic
Polyoxin L is a nucleoside antifungal antibiotic that targets the biosynthesis of chitin in fungal cell walls. It exhibits potent antifungal activity, particularly against rice sheath blight, making it valuable for agricultural research. This compound is useful in studies aimed at understanding fungal resistance mechanisms and developing effective plant protection strategies. -
Lactone
Feigrisolide B is a lactone derived from Streptomyces griseus, exhibiting notable antiviral properties against Coxsackie virus B3 and antifungal activity against Sporobolomyces ochreata. Additionally, it demonstrates moderate inhibitory effects on the enzyme 3α-hydroxysterol dehydrogenase, making it a valuable compound for research into lipid metabolism and infectious diseases. This compound is suitable for studies involving fungal resistance mechanisms and viral pathogenesis. -
Fungi Inhibitor
Acremine I is a potent fungi inhibitor derived from the endophytic fungus Acremonium byssoides. It has demonstrated effective inhibition of Plasmopara viticola, making it a valuable tool for research on plant diseases, particularly grape downy mildew. This compound is useful for studying the mechanisms of fungal resistance and developing strategies for disease management in agriculture. -
β-lactamase Inhibitor
Kalafungin is a β-lactamase inhibitor derived from marine Streptomyces, exhibiting an IC50 value of 225.37 μM. This compound demonstrates potent antimicrobial activity against a range of pathogenic fungi, yeasts, and protozoa, as well as significant effects on gram-positive bacteria like Staphylococcus aureus. Additionally, Kalafungin shows moderate activity against select gram-negative bacteria, making it a valuable tool for research in antibiotic resistance and microbial pathogenesis. -
Antibiotic
Polyoxin M is a nucleoside antifungal antibiotic that targets the synthesis of fungal cell walls. It exhibits potent activity against a wide range of fungal pathogens, particularly demonstrating effectiveness against rice sheath blight. This compound is utilized in research applications focusing on fungal infections and antimicrobial resistance studies. -
Antibacterial Agent
N,O-Diacetyltyramine is an antibacterial agent that exhibits cytotoxic properties. It is derived from the actinomycete Pseudonocardia endophytica VUK-10 and demonstrates activity against both Gram-positive and Gram-negative bacteria, as well as fungi. Additionally, N,O-Diacetyltyramine has been shown to be cytotoxic to various cancer cell lines, including MDA-MB-231, HeLa, MCF-7, and OAW-42, making it a promising candidate for research in antimicrobial and anticancer applications. -
Anti-Fungal Agent
Chondramide D is an anti-fungal agent that specifically targets Candida species, including various yeast forms such as Henson yeast and lipids yeast. This compound demonstrates significant antifungal activity but does not exhibit antibacterial properties against Gram-positive or Gram-negative bacteria. Chondramide D is valuable for research applications focused on fungal infection treatment and understanding yeast-related pathologies. -
Fungicide
Imazalil sulfate is a potent fungicide that primarily targets fungal pathogens in agricultural settings. It exhibits strong activation of the mouse pregnane X receptor (mPXR) while showing minimal interaction with the mouse constitutive androstane receptor (mCAR), indicating its specific metabolic effects. Research indicates that Imazalil sulfate can induce developmental abnormalities, disrupt gut microbiota, and impair hepatic metabolism, making it significant for studies on environmental and toxicological impacts of fungicides. -
Anti-Fungal Agent
Crocacin C functions as an anti-fungal agent, exhibiting significant activity against both yeast and filamentous fungi. In studies, it has been shown to inhibit mouse fibroblast L929 cells, highlighting its potential cytotoxic effects. Additionally, Crocacin C disrupts the bc1 segment of electronic transmission in calf heart microsomes, resulting in a redshift of the 569 nm peak in the cytochrome B reduction spectrum. These properties make it a valuable reagent for research in fungal pathogenesis and cellular bioenergetics. -
Fungal Inhibitor
Mollugogenol A is a potent fungal inhibitor that disrupts cellular integrity in fungal cells. It induces lipid peroxidation, leading to damage to sperm membranes, demonstrating significant sperm-killing activity. This compound is valuable for research applications focused on antifungal mechanisms and reproductive toxicity studies. -
Antibiotic
Hydranthomycin is an antibiotic with notable antifungal properties. It exhibits moderate activity against Pyricularia oryzae, with a minimum inhibitory concentration (MIC) of 25 μg/mL. Additionally, Hydranthomycin inhibits the growth of Euglena gracilis and displays effective herbicidal activity, making it a valuable tool for research in antifungal and herbicide applications. -
Bc1 Complex Inhibitor
bc1 Complex-IN-1 is a potent inhibitor of the bc1 complex, demonstrating significant antifungal activity. This compound effectively exhibits fungicidal properties against Cucumber downy mildew (CDM), making it a valuable tool for studying fungal pathogenesis and potential therapeutic interventions. Its application in research can aid in understanding the mechanisms underlying fungal resistance and the development of effective fungicides. -
Antifungal Agent
Vermistatin is an antifungal agent derived from the fungal strain Guignardia. It exhibits potent cytotoxic and antifungal activities, making it a valuable tool for studying fungal infections and testing antifungal efficacy. This reagent is useful in various research applications, including drug development and the investigation of fungal pathogenesis. -
Antibacterial Agent
Aurachin C is an isoprenoid quinoline alkaloid that functions primarily as a selective inhibitor of terminal oxidases. It exhibits significant antibacterial, antiplasmodial, and antifungal properties, making it a valuable compound for research in infectious disease models. Its mechanism of action and broad-spectrum activity render Aurachin C a useful tool for investigating microbial resistance and developing new antimicrobial therapies. -
Anti-Fungal Agent
Cyclothiazomycin is an antifungal agent that selectively inhibits renin activity while sparing other proteases such as pepsin, aspartic acid, serine, mercaptan protease, and metalloproteinases. Although it demonstrates weak antifungal activity, it serves as a valuable tool in research settings focused on elucidating renin-related pathways and their implications in fungal infections. Its specific inhibition profile makes it a candidate for studies exploring renin's role in various biological processes. -
Fungal CYP51A1 Inh
Becliconazole functions as an inhibitor of the fungal cytochrome P450 51A1 (CYP51A1) enzyme. This compound exhibits significant antifungal activity and is primarily utilized in research related to fungal infections, offering insights into the mechanisms of action and potential therapeutic interventions against fungal pathogens. -
Antifungal Agents
Pradimicin L is an antifungal agent derived from the Streptomyces madurensis species. This homolog of pradimicin A exhibits potent antifungal activity, making it a valuable tool for research in mycology and fungal infection studies. Its efficacy in disrupting fungal cell integrity highlights its potential for further investigation in the development of antifungal therapies. -
Anti-Bacterial Agent
Bagremycin A is an anti-bacterial agent derived from the Streptomyces sp. Tu 4128 strain. It exhibits modest activity against Gram-positive bacteria, as well as the yeast Saccharomyces cerevisiae and the pathogenic fungus Candida albicans. This reagent is utilized in research applications aimed at exploring bacterial resistance mechanisms and the development of novel antimicrobial strategies. -
Anti-Fungal Agent
Haliangicin C is an anti-fungal agent targeting filamentous fungi and oomycetes. It exhibits potent activity against a range of filamentous fungal pathogens, making it a valuable tool for studying fungal infections and their mechanisms. However, it does not demonstrate antibacterial activity, highlighting its specificity for fungal applications in research and therapeutic investigations. -
Anti-Fungal Agent
Ramulosin is an antifungal agent that effectively inhibits the germination of fungal meristems. Its primary mechanism involves disrupting fungal growth, making it a valuable tool for research in mycology and antifungal drug discovery. Ramulosin's activity can aid in understanding fungal pathogenesis and developing targeted therapies against fungal infections. -
Antibiotic
Frenolicin is an antibiotic that primarily targets bacterial pathogens, exhibiting significant antibacterial activity. In addition to its antimicrobial properties, Frenolicin demonstrates cytotoxic effects on tumor cells, making it a valuable compound for research in oncology and infectious disease studies. This dual action positions Frenolicin as a potential candidate for further investigation in therapeutic applications. -
Antibiotic
Mycobacillin is a peptide antibiotic that targets bacterial cell wall synthesis. It exhibits notable antibacterial activity, particularly against Mycobacterium species, making it a valuable reagent in studies of microbial resistance and antibiotic efficacy. Additionally, its antifungal properties allow for exploration in research focused on fungal infections and treatment strategies. -
Antibiotic
Alliacol B is an antibiotic that primarily targets bacterial and fungal pathogens. This compound exhibits weak antibacterial and antifungal activity while inhibiting DNA synthesis in cells of the ascitic form of Ehrlich carcinoma. Its unique mechanism makes it a valuable tool for studies involving cancer cell proliferation and the evaluation of antimicrobial efficacy. -
Macrocyclic dilactone
De-N-methylpamamycin-593A is a macrocyclic dilactone that effectively induces aerial mycelium formation in fungi. This compound serves as a valuable tool in the study of fungal biology, particularly in understanding the mechanisms behind mycelial growth and development. Its unique structure and bioactivity make it pertinent for research in mycology and related fields. -
Chitin Synthase Inhibitor
Asulam potassium is a potent chitin synthase inhibitor that targets the biosynthesis of chitin in fungal cell walls. By disrupting the structural integrity of fungal cells, Asulam potassium effectively impedes normal growth and reproduction, demonstrating significant antifungal activity. This compound is valuable for research applications focused on managing fungal diseases, including downy mildew and gray mold, particularly in crops such as spinach, tulips, daffodils, and lilies. -
Fungicide
PPm is a potent succinate dehydrogenase inhibitor with demonstrated fungicidal activity. It effectively targets fungal respiratory pathways, disrupting energy production and leading to cell death. This compound is widely utilized in agricultural research and studies aimed at understanding fungal resistance mechanisms and developing novel fungicidal strategies. -
Antibiotic
Candicidin D is an antibiotic that exerts its antifungal activity by interacting with steroids in cell membranes. It demonstrates inhibitory effects against Saccharomyces cerevisiae, Candida albicans, and other Candida species, with a minimum inhibitory concentration (MIC) ranging from 0.25 to 1 μg/mL in RPMI-1640 medium. This compound is valuable for research applications focused on fungal pathogenesis and the development of antifungal therapies. -
Antibacterial Agent
1-Methyl-4-nitroimidazole is an antibacterial agent that functions primarily through reduction by bacterial nitroreductases, leading to the generation of toxic derivatives. These derivatives induce DNA damage and inhibit bacterial nucleic acid synthesis, while also producing toxic superoxides that promote bacterial cell death. This compound demonstrates moderate in vitro activity against both bacterial and fungal pathogens and is applicable in research focused on skin infections, purulent infections, and urinary tract infections. -
Antifungal Agent
SPK-843 is a potent antifungal agent that demonstrates significant inhibitory activity against Aspergillus fumigatus (MIC 0.5 μg/mL), Aspergillus flavus (MIC 0.25 μg/mL), and Aspergillus niger (MIC 0.0625 μg/mL). This compound exhibits dose-dependent efficacy in murine models of pulmonary aspergillosis, making it valuable for studying therapeutic strategies for fungal infections. SPK-843 can be employed in various research applications related to antifungal drug development and fungal pathogenesis. -
Anti-Fungal Agent
1,6-Dihydroxy-2-chlorophenazine is a compound that exhibits weak anti-fungal and anti-yeast activity. Its mechanism involves interference with cellular processes in fungi, making it a candidate for research in antifungal drug development. This compound may be utilized in studies investigating the mechanisms of fungal infection and resistance, as well as in screening assays for new therapeutic agents. -
Antitumor Antibiotic
Glidobactin C is an antitumor antibiotic that exhibits significant antifungal activity against pathogenic fungi and yeast, particularly Candida albicans and Aspergillus fumigatus, with a minimum inhibitory concentration (MIC) of 0.8 μg/mL. This compound has demonstrated the potential to extend survival in murine models inoculated with leukemia P388 cells. Research applications include investigating its therapeutic efficacy in cancer and fungal infections, contributing to the development of novel treatments in these areas. -
Antifungal Agent
O-Acetylbenzeneamidinocarboxylic acid serves as an antifungal agent targeting various plant pathogenic fungi. This compound exhibits notable inhibitory activity, making it suited for research applications focused on understanding fungal infections and developing antifungal strategies in agricultural settings. Its effectiveness as a fungal metabolite positions it as a valuable tool in the study of plant pathology. -
Antifungal Agent
Eulicin is an antifungal agent primarily targeting fungal pathogens. It exhibits significant activity against both Gram-positive and Gram-negative bacteria and has demonstrated the ability to inhibit human immunodeficiency virus (HIV) infection and replication. Eulicin is derived from the genus Streptomyces, making it a valuable compound for research in microbial resistance and antiviral therapeutics. -
Antifungal Activity
4-Methyl-6,7-methylenedioxycoumarin is a coumarin derivative that displays significant antifungal activity. It demonstrates effectiveness against Pythium species, making it a valuable tool for research in antifungal applications. This compound is suitable for studies aiming to explore the mechanisms of antifungal resistance and the development of new antifungal agents. -
Antibiotic
2-Hydroxymethylclavam is a β-lactam antibiotic with a primary mechanism of inhibiting bacterial cell wall synthesis. This compound exhibits antifungal activity, particularly against plant pathogenic fungi. It can be utilized in research studies focused on antibiotic resistance and the development of antifungal therapies. -
Antimicrobial Agent
Streptothricin E is a potent antimicrobial agent with broad-spectrum antibacterial and antifungal properties. It exhibits effective inhibitory activity against various bacterial and fungal strains, making it valuable in microbiological research and therapeutic applications. Additionally, Streptothricin E has been shown to inhibit the PR-8 strain of influenza virus in tissue culture, highlighting its potential utility in virology studies. -
Diffusion Signaling Factor
Cis-11-Methyl-2-dodecenoic acid is a diffusion signaling factor (DSF) involved in quorum sensing (QS) within microbial and fungal communication systems. This compound plays a crucial role in regulating virulence and biofilm formation in several bacterial pathogens, making it a valuable tool for research on microbial interactions and pathogenesis. Its application extends to studies aimed at understanding the mechanisms of bacterial communication and the development of strategies to combat bacterial infections. -
Anti-Fungal Agent
Neosordarin is an effective antifungal agent that targets fungal pathogens, including Saccharomyces cerevisiae. It demonstrates potent inhibitory activity with an IC50 value ranging from 0.2 to 0.3 μg/mL. This compound is particularly valuable in research applications focused on understanding fungal resistance and developing antifungal therapies. -
Antifungal Antibiotic
PF-1163B is a potent antifungal antibiotic that targets fungal cell wall synthesis. It exhibits strong inhibitory activity against a range of pathogenic fungi, making it valuable for research into antifungal therapies and mechanisms of resistance. This compound can be utilized in studies aimed at understanding fungal pathogenesis and developing novel treatments for fungal infections. -
Antifungal Agent
Antifungal Agent 113 (compound 9a) is a potent compound targeting fungal and bacterial pathogens. It exhibits significant antifungal and antibacterial activity, specifically against Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA). This compound is valuable for research applications focused on combating resistant infections and exploring antifungal mechanisms.
