Antibiofilm agent-12 is a carbazate derivative with a primary mechanism as an antifungal agent targeting Candida auris. It exhibits significant antifungal activity, demonstrated by a minimum inhibitory concentration (MIC90) of 237.9 μM, and functions by disrupting drug efflux pump activity and promoting ergosterol depletion. This effectively hinders biofilm formation and decreases the metabolic flexibility of Candida auris. Furthermore, Antibiofilm agent-12 has shown efficacy in a C. elegans model infected with Candida auris, highlighting its potential for addressing fungal infections and biofilm-related complications.
Antibiofilm agent-12 is a carbazate derivative with a primary mechanism as an antifungal agent targeting Candida auris. It exhibits significant antifungal activity, demonstrated by a minimum inhibitory concentration (MIC90) of 237.9 μM, and functions by disrupting drug efflux pump activity and promoting ergosterol depletion. This effectively hinders biofilm formation and decreases the metabolic flexibility of Candida auris. Furthermore, Antibiofilm agent-12 has shown efficacy in a C. elegans model infected with Candida auris, highlighting its potential for addressing fungal infections and biofilm-related complications.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
