Catalog No.
Product Name
Application
Product Information
Citations
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Fungal Inhibitor
4-Chlorosalicylic acid is a potent fungal inhibitor that functions primarily by inhibiting monophenolase and diphenolase activities, demonstrating IC50 values of 1.89 mM and 1.10 mM, respectively. It exhibits significant antimicrobial properties, displaying an MIC of 250 μg/mL and an MBC of 500 μg/mL against E. coli. This compound is useful in research applications focused on elucidating mechanisms of fungal and bacterial inhibition. -
Aryltetralin Lignans
α-Peltatin is an aryl lignan that exhibits significant anticancer and antifungal properties. It functions primarily by inhibiting DNA topoisomerase, disrupting DNA replication and repair, and by hindering tubulin polymerization, which impairs microtubule formation. These mechanisms make α-Peltatin a valuable compound for research in cancer biology and antifungal assays. -
Fungicidal Activity
Pinosylvin monomethyl ether primarily targets fungal pathogens, exhibiting notable fungicidal activity. This compound demonstrates antibacterial effects, making it of interest for research in microbiology and pharmacology. Its applications include the study of fungal resistance and the development of antimicrobial agents. -
Antifungal Agent
iKIX1 is an antifungal agent that targets the KIX domain of the mediator subunit CgGal11A, interrupting its interaction with the activation domain of CgPdr1. This compound effectively resensitizes drug-resistant Candida glabrata to azole antifungals in vitro, with inhibition constants IC50 and Ki values of 190.2 μM and 18 μM, respectively. iKIX1 is utilized in research focused on understanding multidrug resistance mechanisms and addressing C. glabrata infections. -
Antifungal Agent
Verazine, an antifungal agent derived from the dried roots and rhizoma of Veratrum maackii Regel, targets fungal pathogens effectively. Its mechanism involves inducing DNA damage in the cerebellum and cerebral cortex of mice in a dose-dependent manner. This compound is relevant for research applications focusing on fungal infections and neurological diseases, offering insights into their underlying mechanisms. -
Antimalarial/Antifungal Agent
Rutarin is a coumarin derivative that exhibits antimalarial and antifungal properties. It effectively inhibits Plasmodium falciparum, demonstrating an IC50 of 88 μg/mL, making it a potential candidate for malaria research. Additionally, Rutarin shows inhibitory activity against Coniophora cerebella, highlighting its utility in antifungal studies. -
Antifungal Agent
Concanamycin C is an antifungal agent that primarily targets the inhibition of lymphocyte proliferation. This compound demonstrates significant antibiotic activity against various fungal and yeast species, making it a valuable tool in antifungal research. It is particularly useful in studies exploring immune responses and fungal pathogenesis. -
Antifungal Agent
Antifungal agent 49 is an antifungal compound designed to target fungal pathogens. It exhibits potent activity against Cryptococcus neoformans, demonstrating a minimum inhibitory concentration (MIC) of 49 μM. This agent can be utilized in research focused on fungal infections and the development of novel antifungal therapies. -
Fungal Inhibitor
(E)-Coniferyl alcohol is a fungal inhibitor that acts as an intermediate in the biosynthetic pathways of eugenol, stilbenoids, and coumarin. This compound demonstrates potent activity against fungal species, making it valuable for studies focused on fungal growth inhibition. Its applications span research on plant defense mechanisms and the development of antifungal agents. -
Antifungal Agent
Diamthazole hydrochloride is an antifungal agent that targets fungal cell membranes. It has demonstrated significant activity against a range of fungal pathogens, making it a valuable tool for infection research. This compound is particularly useful in studying mechanisms of fungal resistance and evaluating potential therapeutic interventions. -
BoNT A Inhibitor
Chaetochromin A is a fungal metabolite that acts as an inhibitor of botulinum neurotoxin serotype A (BoNT A). With an IC50 value of 24.6 μM, it demonstrates significant inhibitory effects, making it a valuable tool for research into neurotoxicology and the mechanistic pathways of neurotoxin action. Its role in understanding BoNT A interactions provides insights for potential therapeutic applications. -
Antimicrobial Agent
Chlorobutanol hemihydrate functions as an antimicrobial agent, demonstrating effectiveness against a range of Gram-positive and Gram-negative bacteria, as well as various fungal spores and fungi. Its preservative properties make it suitable for applications in both the food and cosmetics industries. This compound is valuable for research involving antimicrobial resistance and preservation techniques in different biological contexts. -
Fungal Inhibitor
Isopyrazam serves as a potent fungal inhibitor, demonstrating significant efficacy against various plant pathogenic fungi. Its mechanism of action enhances disease resistance in crops, making it a valuable tool in agricultural research focused on plant protection and disease management. The use of Isopyrazam can lead to improved crop yield and quality, highlighting its potential applications in agro-biological studies. -
Mpro Inhibitor/Anti-Coronaviral Agent
Polycarpine hydrochloride is a potent inhibitor of the main protease (Mpro) with an IC50 of 30 nM, making it a valuable anti-coronaviral agent. This compound, derived from Polycarpa aurata, exhibits significant antiviral properties, demonstrating effectiveness against SARS-CoV-2 Mpro and PEDV Mpro, with IC50 values of 30.0 nM and 0.12 μM respectively. It also possesses antifungal activity, positioning it as a versatile tool for research in virology and infectious diseases. -
Antifungal Agent
Demethoxyencecalin is a chromene compound isolated from Helianthus annuus that exhibits antifungal activity. It targets fungal cell membranes, disrupting their integrity and leading to cell death. This compound is valuable for research applications focused on antifungal activity and the development of novel antifungal agents. -
Antifungal Agent
Methyl orsellinate is an antifungal agent that acts as a 5-lipoxygenase inhibitor, exhibiting an IC50 value of 59.6 μM. This phytotoxic compound demonstrates significant antifungal properties, making it a valuable tool for research on fungal infections. Its ability to inhibit key enzyme pathways highlights its potential in studying antifungal mechanisms and therapeutic applications. -
Fungal Inhibitor
Ethyl Vanillate is a potent fungal inhibitor that primarily targets 17β-hydroxysteroid dehydrogenase type 2 (17β-HSD2), with an IC50 of 1.3 µM. This compound demonstrates significant antifungal properties, making it valuable for research focused on fungal infections and related metabolic pathways. Its ability to modulate steroid hormone activity positions Ethyl Vanillate as an important tool in studies of fungal biology and therapeutic strategies. -
Antibiotic
Asukamycin is a manumycin-type antibiotic derived from Streptomyces nodosus subsp. asukaensis, known for its broad-spectrum antimicrobial properties. This compound exhibits potent antibacterial activity and has been shown to inhibit the growth of various tumor cell lines, making it a valuable reagent for cancer research and antimicrobial studies. -
Fungal Inhibitor
(S,S)-Valifenalate is an acylamino acid fungicide targeting the cell-wall synthesis of Oomycetes fungi. By disrupting the structural integrity of the cell wall, it effectively hinders the growth stages of fungal pathogens, both externally on spores and internally within plant mycelium. This compound is employed in various agricultural research applications aimed at developing strategies for fungal control and improving crop health. -
Antifungal Agent
Mutanocyclin is a highly effective antifungal agent that targets Candida albicans by inhibiting its filamentation. This compound significantly reduces the mRNA expression of key genes involved in fungal morphogenesis, including HWP1, ECE1, FLO8, and TEC1. Additionally, Mutanocyclin has demonstrated the ability to inhibit the yeast form of C. albicans in ex vivo mouse models, making it a valuable tool for research on fungal pathogenesis and potential therapeutic applications. -
Fungal
(Rac)-Dehydrocostus Lactone primarily targets fungal organisms and demonstrates notable antifungal activity. This natural compound also displays a broad range of biological activities, including anti-inflammatory, anticancer, antiviral, and antimicrobial properties. Research applications include investigating its effects on Trypanosoma brucei rhodesiense, as well as exploring its potential in models of diabetes, ulcers, and helminthic infections. Additionally, (Rac)-Dehydrocostus Lactone shows varying IC(50) values in cytotoxicity assays, indicating a favorable selectivity index. -
Succinate Dehydrogenase Inhibitor
Isofetamid is a potent inhibitor of succinate dehydrogenase, primarily utilized as a fungicide. It demonstrates effective control against a range of fungal pathogens, including gray mold, white mold, and powdery mildew. This compound is valuable for research related to plant fungal diseases, contributing to the understanding of fungal inhibition mechanisms and disease management strategies. -
Rapamycin Derivative
7-O-Demethyl rapamycin, a rapamycin derivative, primarily targets the mTOR pathway. This compound exhibits antifungal activity and demonstrates immunosuppressant properties, making it valuable in research related to immune response modulation. Additionally, 7-O-Demethyl rapamycin effectively inhibits tumor cell growth, contributing to studies on cancer biology and therapeutic strategies. -
Coniferin Isomer
(E)-Coniferin is an isomer of Coniferin, a glucoside derived from coniferyl alcohol. This compound exhibits antifungal activity by inhibiting fungal growth and melanization processes. It is useful in research applications focused on fungal pathogenesis and the study of plant defense mechanisms. -
Fungicide
Fuberidazole is a potent fungicide that primarily targets fungal cell growth. It demonstrates a synergistic effect when combined with cucurbituril (CB) macromolecules, particularly CB7 and CB8, enhancing its efficacy. Research indicates that CB8 can induce pKa shifts in Fuberidazole, further improving its antifungal properties. Fuberidazole has been shown to significantly inhibit the growth of Botrytis cinerea, making it a valuable candidate for studies in agricultural and microbiological applications. -
Fungicide
Cymoxanil is a fungicidal cyanooxime that targets plant pathogens within the Perenosporales order. It exerts its biological activity by interfering with fungal growth and affecting DNA and RNA synthesis, particularly in Phytophthora species. This compound is primarily used in agricultural research to study disease management and develop protective strategies against fungal infections in crops. -
Cinnamaldehyde
3-Hydroxy-4-methoxycinnamaldehyde, a derivative of cinnamaldehyde, displays significant antibacterial activity against both Gram-positive and Gram-negative bacteria, as well as antifungal properties with a minimum inhibitory concentration (MIC) ranging from 12.5 to 50 μg/mL. Isolated from the stem bark of Flemingia paniculata, this compound is suitable for research focused on microbial infections and the development of new antimicrobial agents. -
Antibacterial Agents
Benzoic acid lithium is an aromatic compound utilized primarily for its antibacterial properties. It effectively inhibits the growth of bacteria and fungi, making it a valuable preservative in various applications, including food, beverages, and cosmetics. This compound is widely used in research to study antimicrobial mechanisms and develop new preservative formulations. -
Antifungal Agent
Tetradehydropodophyllotoxin is an antifungal agent that exhibits potent inhibitory activity against various fungal pathogens. This compound targets key metabolic processes essential for fungal growth and survival, making it a valuable tool in antifungal research and drug development. Its application spans laboratory studies aimed at understanding fungal resistance mechanisms and evaluating antifungal efficacy. -
Fungal Inhibitor
Thalifoline is an alkaloid recognized for its antifungal properties, primarily targeting fungal cell integrity. Its mode of action involves disrupting fungal growth and proliferation, making it a valuable reagent for research focused on antifungal drug development and potential therapeutic applications against fungal infections. -
Antifungal Alkaloid
Norsanguinarine is an antifungal alkaloid that demonstrates potent activity against fungal pathogens, including Alternaria brassicicola and Curvularia maculans, at concentrations of 1000 ppm. This compound is of interest for research applications focused on the development of natural antifungal agents and the study of plant-microbe interactions. Its mechanism of action may provide insights into novel strategies for controlling fungal diseases in agricultural settings. -
Antifungal Agent
Pseudolaric acid A-O-β-D-glucopyranoside is an antifungal agent isolated from Cortex Pseudolaricis. This compound exhibits notable antifungal properties, making it valuable in research focused on fungal infections and related therapeutic strategies. Additionally, it has shown antifertility activities, providing insights into its multifaceted biological applications. -
Calcineurin Inhibitor
APX879 is a calcineurin inhibitor that selectively targets fungal cells, exhibiting reduced immunosuppressive effects and lower toxicity compared to traditional agents. As a C22-modified analog of FK506, APX879 retains broad-spectrum antifungal activity, making it a valuable tool for studying fungal pathogenesis and the immune response. It holds potential applications in antifungal drug development and research focused on fungal infections. -
Fungal Inhibitor
Saperconazole is a broad-spectrum antifungal triazole that primarily targets fungal growth by inhibiting 14α-demethylase, an enzyme essential for ergosterol biosynthesis. It exhibits potent activity against Aspergillus species, with a minimum inhibitory concentration (MIC90) of 0.19 mg/L. Saperconazole is utilized in research applications involving antifungal efficacy and mechanistic studies of fungal pathogens. -
Fungicide
Flufenoxadiazam is a fungicide that targets fungal pathogens through the inhibition of specific cellular processes. It demonstrates potent fungicidal activity, especially against Phakopsora pachyrhizi and Puccinia triticina. This compound is valuable for agricultural research aimed at managing crop diseases and improving yield in susceptible plant species. -
Fungicide
Fenbuconazole is a triazole fungicide that exerts its activity by inhibiting sterol biosynthesis in fungi. It demonstrates significant antifungal efficacy, with an ED50 of 0.21 μg/mL against M. citri and 1.01 μg/mL against C. acutatum. Additionally, Fenbuconazole has been shown to inhibit human aromatase activity in the JEG-3 choriocarcinoma cell line, leading to increased DNA damage in Allium cepa root cells and a rise in abnormal cell frequency under in vitro conditions. This compound is valuable for research in fungicidal action and mechanisms of DNA damage in cellular models. -
CHS Inhibitor
Chitin Synthase Inhibitor 4 is a selective inhibitor of chitin synthase (CHS), functioning primarily by disrupting chitin biosynthesis in fungal pathogens. This compound demonstrates significant fungicidal activity, making it a promising candidate for agricultural applications aimed at controlling fungal infections. Its mechanism supports research into chitin synthase-targeted approaches in crop protection and fungal biology. -
Antifungal Agent
Mefentrifluconazole is a novel azole derivative that functions as a potent antifungal agent, targeting fungal CYP51 with a Kd of 0.5 nM. This compound exhibits broad-spectrum efficacy against various fungal pathogens while demonstrating significantly lower inhibitory activity on human aromatase, with an IC50 of 0.92 μM. It is suitable for research applications focusing on antifungal therapy and agrochemical development. -
Antifungal Agent
Ticlatone is an antifungal agent that targets fungal cell growth and replication. It exhibits significant activity against various mycoses, making it a valuable tool for studying fungal infections and related therapeutic responses. Ticlatone is suitable for use in research applications focused on the mechanisms of antifungal resistance and the evaluation of potential treatment strategies. -
Fungicide and Preservative
Iodopropynyl butylcarbamate (IPBC) is a broad-spectrum fungicide that effectively inhibits fungal growth by targeting key metabolic pathways. It is commonly utilized as a preservative in various applications, including paints, coatings, wood protection, personal care products, and cosmetics. IPBC's strong antifungal properties make it a valuable reagent for researchers studying fungal resistance and preservation techniques in diverse environments. -
Fungicide
Benodanil is a benzanilide fungicide that targets fungal pathogens in various agricultural applications. It exhibits effective antifungal activity, making it a valuable tool in the management of crop diseases. Researchers utilize Benodanil to study its efficacy and mechanisms of action in combating fungal infections in plants, contributing to improved agricultural practices and yield outcomes. -
Antifungal Peptides
Cyclo(L-Phe-trans-4-OH-L-Pro) is a cyclic peptide that exhibits antifungal activity by disrupting the integrity of fungal cell membranes. This compound is valuable in research focused on developing novel antifungal agents and studying the mechanisms of peptide-based antifungal strategies. Its precise mechanism of action makes it a potential candidate for addressing fungal resistance in clinical settings. -
Siderophore
Bacillibactin, a cyclic tricatecholate siderophore, primarily targets iron acquisition in bacteria by chelating iron ions (Fe3+) from the environment. This mechanism enhances bacterial survival under iron-limited conditions and exhibits direct antimicrobial activity against producing strains such as Pseudomonas aeruginosa and Aeromonas veronae, along with plant pathogens like Pseudomonas syringae. Bacillibactin is suitable for use in antibacterial and antifungal research applications, facilitating studies on microbial pathogenesis and iron metabolism. -
Fungal Inhibitor
Kakuol is a naturally derived compound that acts as a fungal inhibitor, targeting fungal cell growth and proliferation. Exhibiting potent antifungal activity, Kakuol is valuable for research applications involving the investigation of fungal infections and the development of antifungal therapies. Its mechanism of action provides insights into novel approaches for combating fungal pathogens. -
SDH Inhibitor
SDH-IN-2 is a potent inhibitor of succinate dehydrogenase (SDH) with an IC50 value of 0.55 μg/mL, demonstrating strong antifungal activity against phytopathogenic fungi, with an average EC50 range of 3.82-9.81 μg/mL. This compound also features an alkyne group, enabling its application in click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its dual role as an SDH inhibitor and antifungal agent makes SDH-IN-2 a valuable tool for biochemical research and drug development studies focused on metabolic pathways and fungal diseases. -
Fungal Inhibitor
SCH 51048 is a potent fungal inhibitor that generates active metabolites with demonstrated antifungal properties. Research studies have shown that these metabolites exhibit enhanced activity, making SCH 51048 a valuable compound for investigating antifungal mechanisms and evaluating therapeutic options in fungal infections. This compound serves as a useful tool in the study of fungal biology and the development of new antifungal agents. -
Antifungal Agent
4',7-Dimethoxyisoflavone is a naturally occurring isoflavone derived from the leaves of Albizzia lebbeck, exhibiting significant antifungal properties. This compound has been shown to inhibit the growth of various fungal pathogens, making it a valuable reagent for research in antifungal drug development and related studies. Its potential applications extend to investigations focused on the mechanisms of fungal resistance and the exploration of new therapeutic strategies. -
Analogue of Pyrazine-2-carboxamide
Pyrazine-2-amidoxime is a structural analogue of pyrazine-2-carboxamide, primarily targeting microbial organisms. It exhibits significant antimicrobial activity, effectively killing and inhibiting the growth of Candida albicans, a common fungal pathogen, as well as various Gram-positive bacteria. This compound is valuable for research applications focused on antifungal and antibacterial therapies. -
olysaccharide Copolymer
L-Triguluronic acid is a linear polysaccharide copolymer consisting of three L-guluronic acid units. It serves as a precursor to alginate, a class of unbranched polyanionic polysaccharides that exhibits significant biological activities. This compound is particularly useful in research focused on the development of delivery systems for anti-fungal agents, aiding in the exploration of innovative therapeutic strategies.
