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27-O-Demethylrapamycin

Catalog No.: A27587
Antifungal Agent
27-O-Demethylrapamycin, a derivative of Rapamycin, functions primarily as an antifungal agent. It demonstrates significant inhibitory activity against Candida albicans, Saccharomyces cerevisiae, and Fusarium oxysporum. This compound is valuable for research applications focusing on antifungal mechanisms and the exploration of novel therapeutic strategies against fungal infections.
27-O-Demethylrapamycin 141392-23-6 Antifungal Agent
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description27-O-Demethylrapamycin, a derivative of Rapamycin, functions primarily as an antifungal agent. It demonstrates significant inhibitory activity against Candida albicans, Saccharomyces cerevisiae, and Fusarium oxysporum. This compound is valuable for research applications focusing on antifungal mechanisms and the exploration of novel therapeutic strategies against fungal infections.
Product Information
Catalog NumA27587
FormulaC50H77NO13
Molecular Weight900.15
CAS Number141392-23-6
SMILESO=C1N2[C@](CCCC2)([H])C(O[C@](CC([C@@H](/C=C([C@H]([C@H](C([C@@H](C[C@@H](/C=C/C=C/C=C([C@H](C[C@@]3([H])O[C@@](C1=O)([C@@H](CC3)C)O)OC)\C)C)C)=O)O)O)\C)C)=O)([H])[C@H](C)C[C@H]4C[C@H]([C@@H](CC4)O)OC)=O
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Microbiology > Antifection > Fungal