Fig. 1 · Structure
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rel-Avibactam sodium
Cat. No.
A49013
CAS
1383814-68-3
β-lactamase Inhibitor
rel-Avibactam sodium is a potent β-lactamase inhibitor designed to combat bacterial resistance. It demonstrates broad-spectrum antibacterial activity, particularly against Enterobacteriaceae that produce Ambler A and C types of β-lactamases. When used in combination with Cefazidime, rel-Avibactam sodium exhibits significant inhibitory effects and offers enhanced efficiency compared to traditional β-lactamase inhibitors, as indicated by its low IC50 values against TEM-1 and P99 enzymes. This compound is essential for research into antibiotic resistance and the development of novel antibacterial therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1383814-68-3 |
| Applications | β-lactamase Inhibitor |
| Formula | C7H10N3NaO6S |
| Molecular Weight | 287.23 |
| Synonyms | NXL-104 sodium |
| SMILES | NC([C@@H]1[N@]2C(N([C@](CC1)([H])C2)OS(=O)(O[Na])=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.