rel-Avibactam sodium

Catalog No.: A49013
β-lactamase Inhibitor
rel-Avibactam sodium is a potent β-lactamase inhibitor designed to combat bacterial resistance. It demonstrates broad-spectrum antibacterial activity, particularly against Enterobacteriaceae that produce Ambler A and C types of β-lactamases. When used in combination with Cefazidime, rel-Avibactam sodium exhibits significant inhibitory effects and offers enhanced efficiency compared to traditional β-lactamase inhibitors, as indicated by its low IC50 values against TEM-1 and P99 enzymes. This compound is essential for research into antibiotic resistance and the development of novel antibacterial therapies.
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Size Stock
5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptionrel-Avibactam sodium is a potent β-lactamase inhibitor designed to combat bacterial resistance. It demonstrates broad-spectrum antibacterial activity, particularly against Enterobacteriaceae that produce Ambler A and C types of β-lactamases. When used in combination with Cefazidime, rel-Avibactam sodium exhibits significant inhibitory effects and offers enhanced efficiency compared to traditional β-lactamase inhibitors, as indicated by its low IC50 values against TEM-1 and P99 enzymes. This compound is essential for research into antibiotic resistance and the development of novel antibacterial therapies.
Product Information
Catalog NumA49013
FormulaC7H10N3NaO6S
Molecular Weight287.23
CAS Number1383814-68-3
SMILESNC([C@@H]1[N@]2C(N([C@](CC1)([H])C2)OS(=O)(O[Na])=O)=O)=O
SynonymsNXL-104 sodium
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