Catalog No.
Product Name
Application
Product Information
Citations
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Antibiotic
Sakyomicin A is an antibiotic derived from the Actinomycete strain M-53, primarily targeting Gram-positive bacteria. This compound demonstrates significant antibacterial activity, making it valuable for research applications focused on microbial resistance and antibiotic efficacy. Its unique mechanism of action facilitates the exploration of new therapeutic options against Gram-positive infections. -
Antitumor Antibiotic
6-Deoxyilludin M is an antitumor antibiotic that exhibits significant antileukemic activity. This compound can be isolated from the culture broth of the Basidiomycota species, Pleurotus japonicus. It serves as a valuable tool for cancer research, particularly in studies aimed at understanding leukemic processes and developing novel therapeutic strategies. -
Antitumor Antibiotic
Feudomycin A is an antitumor antibiotic that inhibits cancer cell proliferation through its unique cyclic structure. Its biological activity includes the induction of apoptosis in various tumor cell lines, thereby demonstrating potential in cancer research and therapeutic applications. Investigations into its mechanistic pathways can facilitate the development of novel anticancer strategies. -
Antibiotic
Epithienamycin A is a carbapenem antibiotic that exerts its action by inhibiting bacterial cell wall synthesis. It demonstrates significant antibacterial activity against both Gram-positive and Gram-negative bacteria, making it a valuable compound for research in antibiotic efficacy and resistance studies. This reagent is useful for evaluating the mechanisms of bacterial susceptibility and potential therapeutic applications in infectious disease management. -
Antibiotic
Biphenomycin A is a cyclic peptide antibiotic derived from Streptomyces griseorubiginosus 43708. It exhibits significant antibacterial activity and is relevant for research in the field of anti-infection. Its unique structure and mechanism offer potential insights into antibiotic development and resistance studies. -
Cephalosporin Antibiotic
CS 461 is a cephalosporin antibiotic that exhibits potent antibacterial activity against both Gram-positive and Gram-negative bacteria, including certain β-lactamase producing strains. This compound is valuable for research focused on infections, providing a well-balanced approach to tackling diverse bacterial pathogens. Its utility in understanding antibacterial mechanisms makes it a significant reagent in the study of antibiotic resistance and infection treatment strategies. -
Antibiotic
Gentamicin C1 is an aminoglycoside antibiotic that primarily targets bacterial ribosomes to inhibit protein synthesis. It exhibits broad-spectrum antimicrobial activity effective against a variety of Gram-negative and some Gram-positive bacteria. This compound is widely used in research and clinical settings for the treatment of serious infections and for studying antibiotic resistance mechanisms. -
Antibiotic
Arylomycin A5 is a lipohexapeptide antibiotic that targets Gram-positive bacteria through inhibition of bacterial protein synthesis. It demonstrates significant antibacterial activity by interfering with the function of ribosomal RNA, making it a valuable tool in the study of antibiotic resistance and bacterial infections. Arylomycin A5 is suitable for research applications aimed at elucidating the mechanisms of action of antibiotics and developing new therapeutic strategies. -
Antibiotic
(1S,2R,7S)-Sitafloxacin is an antibiotic with potent topoisomerase inhibition targeting DNA gyrase and topoisomerase IV in bacteria. It exhibits significant antibacterial activity, with an IC50 of 0.18 μg/mL against Escherichia coli DNA gyrase and effective action against Staphylococcus aureus. This compound is valuable in the study of various bacterial infections and provides insights into antibiotic resistance mechanisms and therapeutic approaches. -
Antibiotic
Napyradiomycin C1 is an antibiotic that exhibits potent activity against Gram-positive bacteria and mycobacterial strains. It demonstrates minimal efficacy against Gram-negative bacteria and fungi. The compound shows an IC50 of 9.2 µg/mL in leukemia L-1210 cells, indicating its potential application in cancer research and the development of novel therapeutic strategies against specific bacterial infections. -
Antibiotic
Auramycin A is an anthracycline antibiotic targeting Gram-positive bacteria, demonstrating significant antibacterial activity. In addition to its antimicrobial properties, Auramycin A exhibits notable antitumor effects against P388 and L1210 leukemia cell lines in murine models, making it a valuable reagent for research in both infectious diseases and cancer therapies. -
Antibiotic
Pristinamycin IB is an ester peptide antibiotic primarily targeting Gram-positive bacteria. Its mechanism involves inhibiting protein synthesis, leading to antimicrobial activity. Pristinamycin IB is used in research applications aimed at understanding bacterial resistance and testing new therapeutic approaches against resistant strains of Gram-positive pathogens. -
Antibiotic
Haloquinone is a quinone antibiotic that demonstrates potent antibacterial activity against Halobacteria, as well as exhibiting effects against Gram-positive bacteria and mycoplasma. This compound is valuable in researching bacterial resistance mechanisms and the efficacy of novel antibiotic therapies. Its broad-spectrum activity makes it a useful tool for microbiological studies and drug development in the field of infectious diseases. -
Antitumor Antibiotic
Baumycin C1 is an antitumor antibiotic that exerts its biological activity through the inhibition of DNA synthesis. This compound demonstrates potent cytotoxic effects against various cancer cell lines, making it a valuable tool for cancer research. Its mechanism of action and efficacy position Baumycin C1 as a potential candidate for studies investigating novel antitumor therapies. -
Antimicrobial Antibiotic
Sperabillin C is an antimicrobial antibiotic that exhibits potent activity against both Gram-negative and Gram-positive bacteria, including resistant strains such as Pseudomonas aeruginosa and Staphylococcus aureus. Its ability to target a wide spectrum of bacterial pathogens makes it a valuable reagent for research applications in antibiotic resistance studies and the development of new antimicrobial therapies. -
Antibiotic
Pyralomicin 2a is an antibiotic that demonstrates significant antibacterial activity by targeting bacterial cell wall synthesis. It is primarily utilized in research to investigate its effectiveness against various bacterial strains and to explore its potential therapeutic applications in treating bacterial infections. This compound provides a valuable tool for studying antibiotic resistance and the mechanisms of action of antibacterial agents. -
Bacterial Quorum-sensing Molecule
N-3-Hydroxydecanoyl-DL-homoserine lactone is a bacterial quorum-sensing molecule that primarily targets the transcription factor SdiA. It activates SdiA with an EC50 value of 0.6 µM, enabling the detection of N-acyl homoserine lactones (AHLs) in bacterial systems. This compound is particularly relevant for research into the regulation of gene expression in Salmonella enterica and other bacteria, providing insights into quorum sensing mechanisms and potential therapeutic strategies against bacterial infections. -
Antibiotic
Desertomycin B is an antibiotic derived from the guanidino form of a fermentation product of Streptomyces flavofungi. This compound exhibits potent antibacterial activity, demonstrating effectiveness against a range of gram-positive bacteria. Desertomycin B serves as a valuable tool in microbiological research and the study of antibiotic resistance mechanisms. -
Antibiotic
Celesticetin B is an antibiotic that primarily targets Gram-positive bacteria. It exhibits significant antibacterial activity, making it a valuable tool in the study of bacterial infections and resistance mechanisms. This compound is particularly useful for research focusing on the development of new therapeutic strategies against Gram-positive pathogens. -
Antibiotic
Hongoquercin A is a sesquiterpene antibiotic that exhibits moderate activity against Gram-positive bacteria, with a minimum inhibitory concentration (MIC) ranging from 4 to 8 μg/mL. This compound is valuable for research applications focused on antibiotic development and bacterial susceptibility studies. Its unique structure and mechanism of action make it a significant candidate for further exploration in microbial resistance and therapeutic interventions. -
Antibiotic
Lincosamine is a lincosamide antibiotic that inhibits bacterial growth through interference with protein synthesis. Produced by Streptomyces lincolnensis, Lincosamine demonstrates efficacy against various bacterial infections, particularly Klebsiella pneumoniae. Its activity has been benchmarked against other antimicrobial agents, highlighting its relevance in the study of bacterial resistance and the development of new therapeutic strategies. -
Antibiotic
Actiketal is a glutarimide antibiotic that primarily targets bacterial RNA synthesis. It demonstrates potent inhibition of [3H]thymidine incorporation in EGF-stimulated Balb/MK cells, indicating its potential effects on cell proliferation and differentiation. This compound is useful in research applications focused on understanding bacterial resistance mechanisms and exploring the role of antibiotics in cellular responses. -
Antitumor Antibiotic
Cypemycin is a linaridin antibiotic that exhibits antitumor activity by inhibiting cancer cell proliferation. It demonstrates significant cytotoxicity against P388 leukemia cells, with an IC50 of 1.3 μg/mL. Additionally, Cypemycin is effective against various human tumor cell lines, including HeLa S3, HHCC-1, HCCS-M, and Slex, with IC50 values greater than 25 μg/mL. This compound serves as a valuable tool for researching cancer therapeutics and understanding mechanisms of tumor cell resistance. -
Antibiotic
Fluvirucin A1 is an antibiotic that specifically targets the influenza A virus. It exhibits potent antiviral activity, making it a valuable tool for researchers studying influenza infections and potential therapeutic interventions. Fluvirucin A1 can be utilized in preclinical studies to explore mechanisms of viral resistance and efficacy of antiviral compounds. -
Antibiotic
Monamycin G3 is an ester peptide antibiotic that primarily targets Gram-positive bacteria. It exhibits potent antibacterial activity, making it a valuable reagent for investigating bacterial resistance mechanisms and evaluating the efficacy of antimicrobial agents in research settings. Its unique structure and mode of action make it an important tool for studies involving infection models and antibiotic development. -
Antibiotic
PF1140 is a fungal-derived antibiotic that exhibits potent antimicrobial activity against various infectious agents. It is primarily used in the study of infectious diseases, allowing researchers to investigate its efficacy and mechanisms of action. PF1140's unique properties make it a valuable tool for understanding antibiotic resistance and developing new therapeutic strategies. -
Antibiotic
Oxypyrrolnitrin is a nitrogen-containing heterocyclic antibiotic that exhibits broad-spectrum antibacterial and antifungal activity. It demonstrates efficacy against Gram-positive and Gram-negative bacteria, as well as mycobacteria and various fungi. This compound is valuable for research applications focused on combating bacterial resistance and studying fungal infections. -
Antibiotic
3-O-Demethylmonensin A is a polyether antibiotic that functions by disrupting ion transport across cell membranes, primarily targeting bacterial cells. This compound exhibits notable antibacterial activity and has been used in research to study antibiotic mechanisms and resistance. Its specific effects make it valuable for investigating microbial interactions and cellular processes in various biological systems. -
Antibacterial Agent
Cefditoren Pivoxil hydrochloride is a third-generation oral cephalosporin antibiotic with broad-spectrum antibacterial activity, particularly effective against Gram-negative and Gram-positive bacteria. Its enhanced stability against various β-lactamases makes it a valuable tool in studying infectious diseases. Research applications include investigating acute exacerbations of chronic bronchitis, community-acquired pneumonia, streptococcal pharyngitis/tonsillitis, and uncomplicated skin and skin structure infections. -
Antibiotic
Himalomycin A is an anthraquinone antibiotic that exhibits potent antibacterial activity against Staphylococcus aureus, Escherichia coli, and Streptomyces vuridochromogenes. Its mechanism of action involves interference with bacterial DNA synthesis and function, making it a valuable tool for studying antimicrobial resistance mechanisms and assessing bacterial susceptibility in research applications. This compound serves as a useful reagent for investigations in microbiology and antibiotic development. -
Antibiotic
Desmethyl ofloxacin hydrochloride is a primary metabolite of the fluoroquinolone antibiotic ofloxacin, targeting bacterial DNA gyrase and topoisomerase IV. This compound exhibits significant antibacterial activity against a variety of Gram-positive and Gram-negative bacteria. It is utilized in research to investigate mechanisms of antibiotic resistance and to explore the pharmacokinetics of fluoroquinolone antibiotics. -
Antibiotic
Oxamicetin is a nucleoside antibiotic targeting bacterial cell mechanisms. It exhibits potent anti-bacterial activity, particularly against mycobacteria, making it a valuable reagent for research focused on bacterial infections and resistance. Its unique properties facilitate studies in microbiology and contribute to the development of new therapeutic strategies. -
Antibiotic
Lincomycin B is an antibiotic derived from the bacterium Streptomyces lincolnensis. It exhibits potent antibacterial activity against a variety of Gram-positive bacteria, making it valuable for research in microbial pathogenesis and antibiotic resistance. Lincomycin B is often utilized in studies exploring microbial inhibition and the development of novel therapeutics. -
Antibiotic
Norvancomycin is a glycopeptide antibiotic derived from Nocardia orientalis, exhibiting potent antibacterial activity against various strains of Staphylococcus aureus and Staphylococcus epidermidis. This compound is primarily utilized in infection research, providing insights into antibiotic resistance mechanisms and potential therapeutic interventions. Its efficacy in combating Gram-positive bacterial infections makes it a valuable tool for microbiological and pharmacological studies. -
Antibiotic
Monamycin G2 is an ester peptide antibiotic that primarily targets Gram-positive bacteria. This compound exhibits significant antibacterial activity, making it a valuable tool for research into antibiotic resistance and the mechanisms of bacterial infection. Its unique structure and function position Monamycin G2 as a promising candidate for further studies in antibiotic development and microbiological applications. -
Antibiotic
Dactimicin is a pseudodisaccharide aminoglycoside antibiotic that specifically inhibits bacterial protein synthesis. It is effective against methicillin-susceptible Staphylococcus aureus and coagulase-negative staphylococci, demonstrating MIC50s of 2 μg/mL. Dactimicin retains activity against strains that produce aminoglycoside-modifying enzymes, making it a valuable reagent for research on antibiotic resistance and bacterial growth inhibition. -
Antibiotic
Saroaspidin B is an antibiotic compound featuring a dimeric structure derived from phloroglucinol. It exhibits significant antibacterial activity, making it a valuable reagent for studying microbial resistance and antibiotic efficacy. Research applications include investigating mechanisms of action against pathogenic bacteria and exploring potential therapeutic uses in infectious diseases. -
Antibiotic
Propeptin is a peptide antibiotic comprised of 19 amino acids, primarily targeting bacterial infections. It demonstrates selectivity by exhibiting weaker antibacterial activity against Pseudomonas aeruginosa, Mycobacterium monobacterium, and Xanthomonas oryzae. Although Propeptin does not affect KB and L1210 tumor cell lines, it effectively inhibits prolyl endopeptidase, suggesting potential applications in biochemical research and antibiotic development. -
Antibiotic
Sannamycin B is an aminoglycoside antibiotic that primarily targets bacterial ribosomes, inhibiting protein synthesis. While its antibacterial activity is limited to a few bacterial species, it serves as a valuable tool for studying antibiotic mechanisms and resistance. Sannamycin B can be utilized in research applications exploring the efficacy of aminoglycosides and the development of novel antimicrobial strategies. -
Antibiotic
Chrymutasin C is a glycosidic antibiotic known for its antitumor properties. It exerts cytotoxic effects on various cancer cell lines, making it a valuable compound for research applications in cancer treatment and drug development. Its efficacy in disrupting cellular processes highlights its potential as a therapeutic agent in oncology. -
Antibiotic
Cefpimizole sodium is a broad-spectrum cephalosporin antibiotic that targets bacterial cell wall synthesis. It is effective against a variety of Ampicillin-resistant bacteria and demonstrates significant activity against gram-negative species. In addition to its antimicrobial properties, cefpimizole sodium enhances the phagocytic activity of macrophages and neutrophils, making it valuable for research applications in microbiology and immunology. -
Antibiotic
(rac)-Methyl-6-gingerol is an antibiotic derived from Aframomum melegueta. This compound demonstrates significant anti-mycobacterial activity by inhibiting the efflux of toxins in Mycobacterium species. It serves as a valuable tool for research focused on combating mycobacterial infections and studying bacterial resistance mechanisms. -
Antibiotic
Seldomycin factor 5 is an aminoglycoside antibiotic with broad-spectrum antimicrobial activity. It disrupts bacterial protein synthesis by binding to the 30S ribosomal subunit, leading to misreading of mRNA and subsequent inhibition of bacterial growth. Seldomycin factor 5 is utilized in research applications focused on bacterial resistance mechanisms and the development of new antimicrobial therapies. -
Antibiotic
Platenomycin W2 is a macrolide antibiotic that targets bacterial ribosomes to inhibit protein synthesis, specifically effective against Gram-positive bacteria. Its bioactivity makes it a valuable tool in studying bacterial resistance mechanisms and developing new therapeutic agents against infections caused by resistant strains. Researchers can utilize Platenomycin W2 in antimicrobial susceptibility assays and studies focused on the molecular pathways of antibiotic action. -
Antibiotic
Polymyxin B is an antibiotic that primarily targets Gram-negative bacteria by binding with high affinity to lipopolysaccharides (LPS) in the bacterial cell wall. This binding disrupts membrane integrity, leading to increased permeability and ultimately inducing bacterial cell death. Polymyxin B is extensively utilized in research related to endotoxemia due to its ability to neutralize endotoxins and mitigate their harmful effects. -
Bacterial Inhibitor
Lysostaphin targets the bacterial cell wall, acting as an antistaphylococcal agent. This enzyme exhibits the activities of glycylglycine endopeptidase, endo-β-N-acetyl glucosamidase, and N-acetyl muramyl-L-alanine amidase, leading to effective inhibition of Staphylococcus species. Due to its specific enzymatic action, lysostaphin is valuable in research focused on bacterial resistance, pathogen biology, and the development of antimicrobial therapeutics. -
β-lactamase Substrate
Nitrocefin is a chromogenic substrate specifically targeting β-lactamase enzymes. It displays a characteristic color shift from yellow to red upon hydrolysis of the β-lactam ring, enabling visual quantification of β-lactamase activity. This reagent is widely utilized in studies of enzyme inhibition and the development of β-lactamase-resistant antibiotics. -
Antibacterial Agent
Moxifloxacin is an 8-methoxyquinolone antibiotic that functions through the inhibition of bacterial DNA gyrase and topoisomerase IV. It effectively targets a variety of Gram-positive and Gram-negative bacteria, making it useful in the treatment of conditions such as acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia. This compound is valuable for research involving antimicrobial resistance and bacterial infections in clinical microbiology studies. -
Bacterial Inhibitor
Cefotaxime is a third-generation cephalosporin antibiotic that targets bacterial cell wall synthesis. It exhibits broad-spectrum antibacterial activity against a variety of Gram-positive and Gram-negative bacteria and is notably stable against β-lactamase enzymes. This compound is widely used in microbiological research and clinical settings for the treatment and study of bacterial infections. -
Antibiotic
Cefepime is a broad-spectrum cephalosporin antibiotic that effectively targets both Gram-positive and Gram-negative aerobic bacteria. It is characterized by its ability to penetrate the blood-brain barrier, making it suitable for treating central nervous system infections. While it exhibits potent antibacterial activity, it is important to note that cefepime has also been associated with neurotoxicity. This agent is utilized in various research applications focused on antibiotic resistance and infection control.
