Catalog No.
Product Name
Application
Product Information
Citations
-
Bacterial Inhibitor
Thiamphenicol-d3 is a deuterium-labeled variant of the broad-spectrum antibiotic Thiamphenicol, which targets the 50S ribosomal subunit. By binding to this subunit, it inhibits protein synthesis, exhibiting bacteriostatic activity against a wide range of Gram-negative and Gram-positive aerobic and anaerobic bacteria. This reagent is valuable for research applications involving microbiology and the study of antibiotic mechanisms. -
Antibiotic
Platensimycin is an antibiotic derived from Streptomyces platensis that selectively inhibits the biosynthesis of cellular lipids in gram-positive bacteria. It targets the β-ketoacyl-acyl-carrier-protein synthase I/II enzymes, FabF/B, with IC50 values of 48 nM and 160 nM for Staphylococcus aureus and Escherichia coli, respectively. With its unique mechanism of action, Platensimycin shows potential as a therapeutic agent to combat antibiotic resistance. -
Fluoroquinolone Antibiotic
Grepafloxacin hydrochloride is a fluoroquinolone antibiotic that exhibits potent activity against community-acquired respiratory pathogens, particularly Streptococcus pneumoniae. This compound demonstrates high tissue penetration and a favorable pharmacodynamic profile, making it suitable for research applications focused on antimicrobial resistance and respiratory infections. Its unique properties allow for the investigation of effective treatment strategies in microbiology and pharmacology research. -
Antibiotic
Spiramycin I is a macrolide antibiotic that primarily targets bacterial protein synthesis by inhibiting the 50S ribosomal subunit. It exhibits significant antibacterial and antiparasitic activity, making it useful in the treatment of various infections. This reagent is valuable for research applications focused on antimicrobial resistance mechanisms and the development of new therapeutic strategies. -
Antibiotic
Anhydrotetracycline is an antibiotic that functions primarily through the inhibition of tetracycline destructases, thereby preserving the activity of tetracycline antibiotics. This compound demonstrates dose-dependent potency, making it a valuable tool for studying antibiotic resistance mechanisms and enhancing the efficacy of tetracycline-based therapies. Its application in molecular biology and microbiology research helps elucidate bacterial response to antibiotic treatment. -
Antibiotic
Sanfetrinem sodium is a beta-lactamase-stable antibiotic that targets bacterial cell wall synthesis. It exhibits broad-spectrum antibacterial activity against both gram-positive and gram-negative bacteria, making it a valuable reagent for research applications aimed at understanding bacterial resistance mechanisms and developing new antimicrobial therapies. -
β-Lactam Antibiotic
Loracarbef hydrate is a β-lactam antibiotic that belongs to the carbacephem class, exhibiting a synthetic origin. This second-generation cephalosporin antibiotic demonstrates significant antibacterial activity against a variety of Gram-positive and selected Gram-negative bacteria. It is primarily utilized in research applications focused on microbiology and antibiotic resistance studies. -
Antibiotic
Levonadifloxacin is a broad-spectrum antibiotic that targets bacterial infections, particularly against staphylococcal strains. It exhibits potent antibacterial activity against both Methicillin-susceptible Staphylococcus aureus (MSSA) and Methicillin-resistant S. aureus (MRSA). This compound is valuable for research applications focused on the mechanisms of antibiotic resistance and the efficacy of therapeutic strategies in treating resistant infections. -
Bacterial Inhibitor
2,2':5',2''-Terthiophene is a heterocyclic oligomer that primarily targets bacterial inhibition. This compound exhibits significant antimicrobial activity, making it a valuable tool for studying bacterial growth and resistance mechanisms. Additionally, 2,2':5',2''-Terthiophene serves as an essential building block in the synthesis of organic semiconductor materials, particularly polythiophene, which has applications in electronic devices and sensors. -
Antibacterial agent
Lascufloxacin is a potent fluoroquinolone antibacterial agent that effectively targets bacterial DNA gyrase and topoisomerase IV, leading to DNA replication inhibition. It demonstrates significant activity against a range of pathogens, including strains resistant to traditional quinolone therapies. Lascufloxacin is primarily applicable in the treatment of various infectious diseases, particularly lower respiratory tract infections. -
Antibiotic
Kendomycin ((−)-TAN 2162) is a polyketide antibiotic primarily targeting bacterial growth inhibition. It exhibits significant antibacterial activity, particularly against methicillin-resistant Staphylococcus aureus (MRSA) with a minimum inhibitory concentration (MIC) of 5 μg/mL. In addition to its antibacterial properties, Kendomycin acts as a potent antagonist of the endothelin receptor and a calcitonin receptor agonist, highlighting its potential applications in anti-osteoporotic research. -
Antibiotic
AMOZ, a metabolite associated with Furaltadone, functions as an antibiotic by forming stable tissue residues through covalent binding to proteins. This property allows for the coupling of AMOZ with carrier proteins, such as BSA or OVA, to elicit an immune response and release upon acid hydrolysis. AMOZ is instrumental in monitoring antibiotic residues in animal-derived foods, with detection capabilities via competitive ELISA methods achieving limits as low as 0.16 μg/kg in shrimp samples. Its utility makes it a critical marker in food safety research. -
Antibiotic
PAMAM Dendrimer G0.0 amine is an antibiotic targeting pore-forming toxins, specifically acting as an antagonist to anthrax toxin protective antigen 63 (PA63, IC50 = 231 nM) and C. botulinum C2 toxin subunit (C2IIa, IC50 = 940 nM). At concentrations of 10 and 20 µM, it demonstrates protective effects against C2 toxin-induced cytotoxicity in HeLa cells. Additionally, this compound acts as a nickel chelator and has been employed in the selective capture and storage of carbon dioxide in gas-feed systems when used in conjunction with polysulfone membrane-bound chitosan. PAMAM Dendrimer G0.0 amine serves as a valuable reagent in research focused on infectious diseases, cancer biology, and drug delivery systems. -
Glycopeptide Antibiotic
A40926 is a glycopeptide antibiotic that targets the bacterial cell wall peptidoglycan precursor D-alanyl-D-alanine (D-Ala-D-Ala). It functions by irreversibly inhibiting cell wall synthesis through competitive binding, demonstrating significant bactericidal activity against Gram-positive bacteria, including Staphylococcus and Streptococcus, as well as Neisseria gonorrhoeae, with MIC values ranging from 0.06 to 2 μg/mL. Additionally, A40926 is effective against penicillin-resistant strains, disrupting peptidoglycan cross-linking and leading to bacterial lysis and death. The compound's fat-soluble fatty acid structure enhances serum concentrations and extends its duration of action, with a terminal half-life of 61.22 hours in rats. -
Antibiotic Peptide
Dermcidin-1L (human) is an antibiotic peptide that targets microbial pathogens with its inherent antimicrobial activity. Secreted by sweat glands, it plays a crucial role in skin defense mechanisms. Research applications include studies of inflammatory skin disorders and the investigation of innate immune responses. -
Antibiotic
Indolmycin is a competitive inhibitor of prokaryotic tryptophanyl-tRNA synthetase (TrpS), serving as an effective antibiotic. This compound exhibits significant antibacterial and antiviral properties, making it valuable in various research applications focused on microbial resistance and viral infection mechanisms. Its unique mode of action allows for exploration into strategies for combating infectious diseases. -
Antibiotic
Ristocetin A sulfate is an antibiotic primarily targeting staphylococcal infections. Its biological activity includes promoting thrombocytopenia and platelet agglutination. Ristocetin A sulfate is instrumental in two important assays: the ristocetin cofactor assay and the ristocetin-induced platelet aggregation assay, both of which are utilized in diagnosing von Willebrand disease and various bleeding disorders. -
Antibiotic
trans-Clopenthixol dihydrochloride is an antibiotic agent that exhibits activity against Pseudomonas aeruginosa and Plasmodium falciparum in vitro, while lacking neuroleptic effects. This compound is valuable for research applications focusing on bacterial and parasitic infections. Its structural properties enable investigations into potential therapeutic pathways for managing these pathogens. -
Antibiotics
Sulfathiazole-d4 is a deuterium-labeled variant of Sulfathiazole, which serves as a selective antibiotic with specific endocrine-disrupting properties. It primarily targets the steroidogenic pathway by enhancing the activity of CYP19 in human adrenal cancer cells (H295R) while upregulating mRNA expression of CYP17, CYP19, and 3β-HSD. This compound is instrumental in increasing the production of 17-estradiol (E2) and has been shown to exert endocrine-disrupting effects in aquatic organisms, including species such as the Japanese medaka fish, making it a valuable tool for studies on endocrine disruption and steroid metabolism. -
Bacteriostatic Antibiotic
Trimethoprim hydrochloride is a bacteriostatic antibiotic that functions primarily as a dihydrofolate reductase inhibitor. It exhibits efficacy against a broad spectrum of Gram-positive and Gram-negative aerobic bacteria, making it valuable in the study of urinary tract infections, Shigellosis, and Pneumocystis pneumonia. Additionally, trimethoprim hydrochloride has been shown to inhibit Influenza A virus infection in chick embryos when combined with zinc, highlighting its potential for further virological research applications. -
GAK Inhibitor
GAK Inhibitor 2 is a selective inhibitor of cyclin G-associated kinase (GAK), exhibiting a potent IC50 value of 0.024 μM. This compound demonstrates significant antiviral activity, with an effective concentration (EC50) of 1.049 μM against dengue virus (DENV). GAK Inhibitor 2 is suitable for research exploring GAK's role in viral pathogenesis and therapeutic strategies against DENV. -
Cephalosporin Antibiotic
Cephalexin hydrochloride is a semisynthetic cephalosporin antibiotic that exhibits potent activity against a broad spectrum of gram-positive and gram-negative bacteria. It acts primarily by targeting penicillin-binding proteins (PBPs), leading to the inhibition of bacterial cell wall synthesis. This compound is commonly utilized in research related to bacterial infections, including pneumonia, streptococcal throat infections, and bacterial endocarditis. -
Antibiotic
Hordenine hydrochloride is an alkaloid known for its antibiotic properties and its mechanism of action involves the inhibition of melanogenesis through the suppression of cyclic adenosine monophosphate (cAMP) production. This compound is of significant interest in research focused on skin biology and pigmentation processes. Additionally, hordenine hydrochloride may be explored for its potential therapeutic applications in various dermatological conditions. -
Veterinary Antibiotic
Nifursol is an orally active veterinary antibiotic that targets Histomonas meleagridis, effectively preventing histomoniasis in turkeys. This agent is utilized in research focused on Escherichia coli gastroenteritis, particularly in the context of Salmonella infections in poultry and aquatic animals. Its application in veterinary medicine supports studies investigating antibiotic efficacy and disease prevention in livestock. -
Antibiotic
trans-Clopenthixol is an antibiotic that exhibits no neuroleptic effects. It has demonstrated the ability to inhibit the growth of Pseudomonas aeruginosa and Plasmodium falciparum in vitro. This compound may be valuable for research applications focused on bacterial and parasitic infections. -
Aminoglycoside Antibiotic
Neamine tetrahydrochloride is an aminoglycoside antibiotic that exhibits broad-spectrum antibacterial activity. It serves as an anti-angiogenesis agent by specifically targeting angiogenin, contributing to its antitumor properties. Additionally, Neamine tetrahydrochloride demonstrates neuroprotective effects, making it valuable in various biomedical research applications, including studies focused on cancer and neurodegenerative diseases. -
Cephalosporin Antibiotic
Ceftaroline fosamil hydrate is a potent cephalosporin antibiotic that targets bacterial cell wall synthesis. It exhibits broad-spectrum efficacy against Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA) and multidrug-resistant Streptococcus pneumoniae, as well as common Gram-negative bacteria. This compound is valuable for research focused on complicated skin and skin structure infections (cSSSIs) and community-acquired bacterial pneumonia (CABP). -
Antibiotic
Ribostamycin is a broad-spectrum aminoglycoside antibiotic that targets bacterial protein synthesis, primarily by binding to the ribosome. It exhibits activity against both Gram-negative and Gram-positive bacterial infections. Additionally, Ribostamycin has been shown to inhibit the chaperone activity of protein disulfide isomerase (PDI), making it useful in various research applications related to microbial resistance and protein folding studies. -
β-lactamase Inhibitor
Sulbactam pivoxil is a prodrug of Sulbactam, functioning primarily as a β-lactamase inhibitor. It demonstrates significant antibacterial activity by overcoming resistance mechanisms associated with β-lactam antibiotics. This compound is characterized by enhanced absorption compared to Sulbactam, leading to elevated serum concentrations following oral administration, making it a valuable tool for research on antibiotic resistance and evaluation of combination therapies. -
Antibiotic
Nybomycin is an antibiotic that demonstrates significant antiphage and antibacterial activity. It functions by binding to DNA, resulting in distinctive morphological alterations in mycobacterial bacilli, ultimately leading to bacterial cell death. This compound is valuable in research applications focused on understanding bacterial resistance and developing new antimicrobial therapies. -
Cephalosporin Antibiotic
Cefteram pivoxil is an orally active cephalosporin antibiotic that targets bacterial cell wall synthesis. Its primary mechanism involves the inhibition of penicillin-binding proteins, leading to bacterial lysis and death. This compound exhibits broad-spectrum antibacterial activity and is commonly utilized in the treatment of various bacterial infections, including respiratory and urinary tract infections. -
Bacterial Inhibitor
Moxifloxacin hydrochloride monohydrate is a potent bacterial inhibitor that targets DNA gyrase and topoisomerase IV, leading to the disruption of bacterial DNA replication and transcription. It exhibits strong efficacy against Streptococcus pneumoniae and is primarily utilized in the study of bacterial infections, including research on tuberculosis. Its oral bioavailability and broad-spectrum activity make it a valuable reagent for microbiological studies and antibiotic efficacy testing. -
Cephamycin Antibiotic
Cefmetazole is a semisynthetic cephamycin antibiotic that targets penicillin-binding proteins (PBPs) to inhibit bacterial cell wall biosynthesis. With broad-spectrum antibacterial activity, it effectively combats gram-positive, gram-negative, and anaerobic bacteria. Cefmetazole is commonly utilized in research focused on gynecologic, intraabdominal, urinary tract, respiratory tract, and skin and soft tissue infections. -
Antibiotic
Alafosfalin is a phosphonodipeptide that functions as an inhibitor of cell wall biosynthesis. It exhibits antibacterial activity, making it a valuable tool for research in the study of bacterial infections and the mechanisms of antibiotic resistance. This compound is applicable in investigations focusing on cell wall integrity and the development of novel antibacterial strategies. -
Antibiotic
Cefixime trihydrate is a third-generation cephalosporin antibiotic that targets bacterial cell wall synthesis. It exhibits broad-spectrum activity against various gram-positive and gram-negative bacteria, making it effective for treating a range of bacterial infections, including urinary tract infections and respiratory tract infections. This compound is valuable in microbiological research and the study of antibiotic resistance mechanisms. -
Bacterial Inhibitor
Helvolic acid, also known as Fumigacin, is a natural antibiotic derived from Xylaria sp. It exhibits potent activity against Gram-positive bacteria, making it a valuable tool for investigating bacterial inhibition. This compound can be utilized in microbiological studies to explore mechanisms of antibiotic action and resistance. -
Antibiotic
Fluoroquinolonic acid is a bacteriostatic antibiotic that primarily targets bacterial DNA gyrase and topoisomerase IV. This compound demonstrates broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria, making it useful in various microbiological studies. Its ability to inhibit bacterial growth positions it as a valuable reagent for research applications in antibiotic resistance and pathogen profiling. -
Lipopeptide Antibiotic
Globomycin is a lipopeptide antibiotic that acts as an irreversible inhibitor of signal peptidase II (LspA). By binding to the peptidase, Globomycin disrupts the processing of prolipoproteins, demonstrating significant antibacterial activity against the mollicute Spiroplasma melliferum with a minimum inhibitory concentration (MIC) of 6.25-12.5 μM. This compound is valuable for research applications focused on bacterial protein processing and antibiotic resistance mechanisms. -
Antibiotic
AMOZ-d5 is a deuterated form of AMOZ, a tissue-bound metabolite of the synthetic nitrofuran antibiotic Furaltadone. This compound exhibits potent antibacterial activity and is primarily utilized in research to study the pharmacokinetics and metabolism of nitrofuran antibiotics. Its stable isotopic labeling allows for detailed analytical investigations in various biological samples. -
Chloramphenicol-Like Antibiotic
Azidamfenicol is a chloramphenicol-like antibiotic that functions by inhibiting ribosomal peptidyltransferase with a Ki value of 22 μM. This broad-spectrum agent exhibits significant antibacterial activity, making it useful in studying bacterial protein synthesis. Additionally, Azidamfenicol serves as a click chemistry reagent due to the presence of an azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules, DBCO, or BCN groups. This dual functionality allows for versatile applications in chemical biology and bioconjugation strategies. -
Antibiotic
Mellein is an antibiotic derived from the culture fluids of Aspergillus species. This compound exhibits potent antibacterial activity, making it valuable in studying microbial resistance and the mechanisms of action of antibiotics. Its application extends to various fields of microbiological research and drug development, providing insights into potential therapeutic uses. -
Antibiotic
Cefalonium is a first-generation β-lactam cephalosporin antibiotic targeting bacterial cell wall synthesis. It exhibits potent activity against Gram-positive bacteria, particularly staphylococci, making it a valuable tool for studying bovine mastitis. This compound is essential for research applications focused on bacterial infections and antibiotic resistance mechanisms in veterinary medicine. -
Antibiotic
Ulifloxacin is a broad-spectrum quinolone antibiotic that targets bacterial DNA gyrase and topoisomerase IV, inhibiting bacterial DNA replication and transcription. It demonstrates potent antibacterial activity against a variety of Gram-positive and Gram-negative pathogens. Due to its efficacy, Ulifloxacin is utilized in research applications focused on infectious diseases and the development of novel antibacterial therapies. -
HIV-1 Inhibitor
Formycin A is a purine nucleoside antibiotic that acts as a potent inhibitor of human immunodeficiency virus type 1 (HIV-1), exhibiting an EC50 of 10 μM. This compound demonstrates notable antiviral and antitumor activities, making it a valuable tool for research in virology and cancer biology. Its efficacy against HIV-1 makes it a relevant candidate for studies aimed at developing antiviral therapies. -
β-lactam Antibiotic
Azidocillin is a semi-synthetic β-lactam antibiotic that exhibits oral bioavailability and retains its antibacterial activity against various pathogens. Featuring an azide group, Azidocillin serves as both a therapeutic agent and a versatile click chemistry reagent, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition reactions with alkyne-containing compounds. It may also undergo strain-promoted azide-alkyne cycloaddition (SPAAC) with DBCO or BCN groups. This compound is valuable for investigating osteitis resulting from dental procedures, otitis media, enterococcal septicemia, and other bacterial infections. -
Antibiotic Agent
Metronidazole acetic acid is a metabolite of metronidazole that exhibits mutagenic activity in bacterial systems. As a nitroimidazole antibiotic, it is effective against anaerobic bacteria and protozoa, making it valuable for research in antimicrobial resistance and infectious disease models. Its unique properties allow for exploration of mutagenesis and metabolism in microbial contexts, supporting various biochemical studies. -
Antibiotic
Penicillin G benzathine tetrahydrate is a beta-lactam antibiotic that functions by inhibiting bacterial cell wall synthesis. It possesses potent activity against a wide range of Gram-positive bacteria, making it effective in treating various bacterial infections, including rheumatic fever and syphilis. This compound is commonly utilized in clinical and research settings to study antibiotic resistance and the pharmacokinetics of penicillin derivatives. -
Antibiotic
Aurachin SS is an antibiotic compound derived from the natural product isolated from Streptomyces sp. NA04227. It exhibits significant antibacterial activity, making it a valuable tool for research into microbial resistance and the development of new antimicrobial strategies. This compound is suitable for investigations in microbiology and therapeutic applications targeting bacterial infections. -
Macrolide Antibiotic
Erythromycylamine is a macrolide antibiotic that primarily targets bacterial ribosomes, inhibiting protein synthesis. It exhibits significant antibacterial activity against a range of Gram-positive cocci and Moraxella catarrhalis. This reagent is valuable for research applications focusing on bacterial resistance, antibiotic efficacy studies, and the mechanisms of action of macrolide antibiotics. -
Antibacterial Agent
SABA1 is an antibacterial agent that exhibits significant activity against Pseudomonas aeruginosa and Escherichia coli. With an IC50 of 4.0 µM against E. coli ACC, SABA1 is a valuable tool for researching bacterial infections and antimicrobial resistance in various biological studies.
