Leotiomycene C

Catalog No.: A27657
Antifungal Agent
Leotiomycene C is an isoprenylated bisresorcinol derivative derived from the freshwater fungus Helotiales sp., functioning primarily as an antifungal agent. This compound effectively disrupts the quorum sensing mechanisms of methicillin-resistant Staphylococcus aureus (MRSA), exhibiting an IC₅₀ value between 6.3 and 12.5 μM. Leotiomycene C is relevant for research focused on combating MRSA infections and understanding quorum sensing pathways in pathogenic bacteria.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLeotiomycene C is an isoprenylated bisresorcinol derivative derived from the freshwater fungus Helotiales sp., functioning primarily as an antifungal agent. This compound effectively disrupts the quorum sensing mechanisms of methicillin-resistant Staphylococcus aureus (MRSA), exhibiting an IC₅₀ value between 6.3 and 12.5 μM. Leotiomycene C is relevant for research focused on combating MRSA infections and understanding quorum sensing pathways in pathogenic bacteria.
Product Information
Catalog NumA27657
FormulaC19H20O3
Molecular Weight296.36
CAS Number2293113-73-0
SMILESOC1=C2C(/C=C(C)\C)C3=C(O)C=C(C)C=C3OC2=CC(C)=C1
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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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