Arborcandin B

Catalog No.: A27654
1,3-β-glucan Synthase Inhibitor
Arborcandin B is a potent inhibitor of 1,3-β-glucan synthase, functioning as an antifungal agent. It demonstrates notable biological activity with IC50 values of 0.30 μg/mL against Candida albicans and 0.025 μg/mL against Aspergillus fumigatus. Arborcandin B also reveals a minimum inhibitory concentration (MIC) of 2-4 μg/mL against various species within the genus Candida, making it a valuable tool for research in antifungal mechanisms and therapies.
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5mg
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionArborcandin B is a potent inhibitor of 1,3-β-glucan synthase, functioning as an antifungal agent. It demonstrates notable biological activity with IC50 values of 0.30 μg/mL against Candida albicans and 0.025 μg/mL against Aspergillus fumigatus. Arborcandin B also reveals a minimum inhibitory concentration (MIC) of 2-4 μg/mL against various species within the genus Candida, making it a valuable tool for research in antifungal mechanisms and therapies.
Product Information
Catalog NumA27654
FormulaC58H103N13O18
Molecular Weight1270.51
CAS Number223465-78-9
SMILESNC(C(O)CC1C(N[C@](C(N[C@@](C(NC(C(NCC(NCCC(NC(C(N[C@@H](C(N[C@H](C(N[C@@H](C(N1)=O)C)=O)CC(N)=O)=O)CC(N)=O)=O)CCCCCCCC(O)CCCCC)=O)=O)=O)CCC(O)CCCCCCCCC)=O)([H])[C@H](O)C)=O)([H])[C@H](O)C)=O)=O
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