Senkyunolide B is a naturally occurring phthalide derived from Angelica sinensis, exhibiting potent antifungal activity. It effectively inhibits the spore germination and hyphal growth of Aspergillus fumigatus by down-regulating the phosphatidylinositol-PKC-calcineurin signaling pathway and the expression of ENG genes. This compound is a valuable tool for research in antifungal drug development and pathogenic fungal biology.
Senkyunolide B is a naturally occurring phthalide derived from Angelica sinensis, exhibiting potent antifungal activity. It effectively inhibits the spore germination and hyphal growth of Aspergillus fumigatus by down-regulating the phosphatidylinositol-PKC-calcineurin signaling pathway and the expression of ENG genes. This compound is a valuable tool for research in antifungal drug development and pathogenic fungal biology.
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