Other inhibitors

Dimethyl 4-hydroxyisophthalate is a methyl salicylate analogue.

TAK-778 is a derivative of ipriflavone and has been shown to induce bone growth in in vitro and in vivo models.

CP 375 is a Fe3+ chelating agent, with a log K1 value of 14.50.

TOK-8801 is a synthesized dihydroimidazothiazole carboxamide and is under development as an immunomodulator.

3-arylisoquinolinamine derivative is a 3-arylisoquinolinamine derivative with antitumor activity.

CI-943 is a potential antipsychotic agent.

Bupranolol is a non-selective beta blocker without intrinsic sympathomimetic activity (ISA), but with strong membrane stabilizing activity.

Nisoxetine hydrochloride is a selective and potent inhibitor of norepinephrine transporter with little or no affinity for a range of other neurotransmitter receptors. Nisoxetine hydrochloride is an inhibitor of SLC6A2.

Ruzadolane (UP 26-91) is a non-narcotic, centrally-acting analgesic agent.

N/A

L161240, was active against a P. aeruginosa construct in which the endogenous lpxC gene was inactivated and in which LpxC activity was supplied by the lpxC gene from E. coli.

GSK369796 Dihydrochloride Shows antimalerial activity with IC50 values of 11.2 nM for 3D7 strain, 12.6 nM for HB3 strain, 17.6 nM for K1 strain

Golotimod is an orally bioavailable synthetic peptide containing the amino acids D-glutamine and L-tryptophan connected by a gamma-glutamyl linkage with potential immunostimulating, antimicrobial and antineoplastic activities.

3,4-Dehydro Cilostazol is a metabolite of Cilostazol.

4'-trans-Hydroxy Cilostazol is a metabolite of Cilostazol.

NAV-2729 is a dual Arf1/Arf6 activation inhibitor.

NBTGR (p-Nitrobenzylthioguanosine) is a potent inhibitor of nucleoside transport; inhibits adenosine uptake with a Ki of 70 nM.

BMS-747158-02 is a fluorine 18?Clabeled pyridaben derivative designed as a new myocardial perfusion imaging agent for use with positron emission tomography (PET).

N-Methyl Metribuzin is an aminotriazinone and the methylamine analogue of the herbicide Metribuzin.

Metazathioprine is a methylated derivative of azathioprine (AZA). It demonstrated the greatest values of apparent and specific partition coefficients in n-octanol/phosphate buffer at pH 5.7 and pH 7.4 among purine derivatives such as 6-mercaptopurine (6-MP), 6-thioguanine (6-TG) and AZA.

CB-184 is a useful tools for characterization of sigma 2 receptors.

Coluracetam(MKC-231) is a new choline uptake enhancer.

Isatoribine monohydrate is a novel guanosine analogue showing immunostimulatory activity both in vivo and in vitro. This compound acts on different components of the immune system including B cells, natural killer (NK) cells and antigen-presenting cells (APC).

PKR Inhibitor is an oxindole/imidazole derivative that binds the ATP-binding site of PKR and blocks autophosphorylation with an IC50 value of 186-210 nM.3 PKR Inhibitor protects human neuroblastoma cells against cell damage triggered by tunicamycin-mediated endoplasmic reticulum stress.

CHR-6494 is a potent and selective Haspin (Haploid Germ Cell-Specific Nuclear Protein Kinase) inhibitor that blocks H3T3ph phosphorylation.

GZ-793A is a selective inhibitor of vesicular monoamine transporter 2 (VMAT2), which transports the monoamine neurotransmitters from cellular cytosol into synaptic vesicles.

N-(p-Coumaroyl) Serotonin is an antibacterial agent which inhibits the production of proinflammatory cytokines by LPS-stimulated human blood monocytes.

5-Bromo Brassinin is a derivative of Brassinin.

N-Bis(2-hydroxypropyl)nitrosamine is an agent with carcinogenic activity.

7-Methyluric Acid is a metabolite of Theobromine.

3-Methylcrotonyl Glycine is a metabolite found in 3-methylcrotonylglycinuria, a metabolic disorder.

6-Maleimido-1-hexanol is a maleimide compound with a pendant hexanol moiety.

cis-Urocanic acid is a major ultraviolet-absorbing component of the stratum corneum.

a-Hydroxyglutaric acid (2-HG) is an a-hydroxy acid. It is normally metabolized to 2-oxoglutarate by D- and L-2-hydroxyglutarate dehydrogenases, and mutations in these enzymes cause 2-hydroxyglutaric aciduria, a neurometabolic disorder.

Etofenamate is an anti-inflammatory, anti-arrhythmic amino acid.

Anticancer agent 3 (Compound 4) is a anti-cancer agent.

Nifuratel is used as an antibacterial, antifungal, and antiprotozoal (Trichomonas).

Phloroglucinol is a hygroscopic biochemical that is also potentially useful for bone decalcification in microscopy specimens or the detection of wood fibers.

Gefarnate is a synthetic isoprenoid that is used to treat chronic gastric and duodenic ulcers.

Levomefolic acid is the primary biologically active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine.

PTZ-343 is a phenothiazine derivative with chemical name: sodium 3-(10H-phenothiazin-10-yl)propane-1-sulfonate.

Gemcitabine elaidate is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity.

NBMPR is a nucleoside analog that competitively inhibits the equilibrative nucleoside transporter 1 (Kd = 0.1-1.0 nM, IC50s = 4.6 and 3.6 nM in rat and human, respectively).

NSI-189 is a nootropic and neurogenic research chemical derived from nicotinamide and pyrazine.

SCH 54292 is a novel GDP exchange inhibitor

5S rRNA modificator is a suitable electrophile for 2?€?-hydroxyl acylation on structured RNA molecules, yielding accurate structural information comparable to that obtained with existing probes; 5S rRNA RNA modification.

Cambendazole acts as an anthelmintic used in the treatment of Chagas?€? disease.

ST 101 (ZSET1446) is a novel cognitive enhancer that promotes hippocampal neurogenesis and ameliorates depressive behavior in olfactory bulbectomized mice.

Ononetin is a naturally occurring deoxybenzoin.

Tirofiban, Hydrochloride Hydrate is a specific nonpeptide platelet fibrinogen receptor (GPIIb/IIIa) antagonist.