Other inhibitors

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  1. Oxibendazole is a benzimidazole drug that is used to protect against roundworms, strongyles, threadworms, pinworms and lungworm infestations in horses and some domestic pets.
  2. Tioconazole is an antifungal medication of the imidazole class used to treat infections caused by a fungus or yeast.
  3. Tolnaftate is a synthetic thiocarbamate used as an anti-fungal agent. It is believed to inhibit the squalene epoxidase, an important enzyme in the biosynthetic pathway of ergosterol (a key component of the fungal membrane) in a similar way to allylamines.
  4. Prulifloxacin is an older synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class. Like other fluoroquinolones, Prulifloxacin prevents bacterial DNA replication, transcription, repair and recombination through inhibition of bacterial DNA gyrase.
  5. Rimantadine is an orally administered antiviral drug used to treat, and in rare cases prevent, influenzavirus A infection. Rimantadine is believed to inhibit influenza's viral replication, possibly by preventing the uncoating of the virus's protective shells, which are the envelope and capsid.
  6. Isepamicin (also Isepamycin) is an aminoglycoside antibiotic.
  7. Noradrenaline bitartrate monohydrate (Levophed) is a direct alpha-adrenergic receptors stimulator.
  8. Inulin and its analog sinistrin are used to help measure kidney function by determining the glomerular filtration rate (GFR). It is also used for rehydration and remineralization following important loss of water, like diarrhea and diaphoresis. Inulin can also be used as a vaccine adjuvant.
  9. ATP (Adenosine-Triphosphate) is a nucleoside triphosphate used in cells as a coenzyme. It is often called the "molecular unit of currency" of intracellular energy transfer. ATP transports chemical energy within cells for metabolism. It is one of the end products of photophosphorylation, cellular respiration, and fermentation and used by enzymes and structural proteins in many cellular processes, including biosynthetic reactions, motility, and cell division.
  10. Risedronic acid is a bisphosphonate used to strengthen bone, treat or prevent osteoporosis, and treat Paget's disease of bone.
  11. Genipin is a chemical compound found in gardenia fruit extract. Genipin is an excellent natural cross-linker for proteins, collagen, gelatin, and chitosan cross-linking. Furthermore, genipin can be used as a regulating agent for drug delivery, as the raw material for gardenia blue pigment preparation, and as the intermediate for alkaloid syntheses. In vitro experiments have shown that genipin blocks the action of the enzyme uncoupling protein 2.
  12. NAD+ is a major electron acceptor molecule in biological oxidations.
  13. Etidronic acid is a bisphosphonate used to strengthen bone, treat osteoporosis, and treat Paget's disease of bone. An etidronate is a salt of etidronic acid, abbeviated MnHEDP. Etidronate, unlike other bisphosphonates, also prevents bone calcification.
  14. Pamidronic acid is a nitrogen containing bisphosphonate, used to prevent osteoporosis. It is also used to strengthen bone in Paget's disease, to prevent bone loss due to steroid use, and in certain cancers with high propensity to bone, such as multiple myeloma.
  15. Fluocinonide is a potent glucocorticoid steroid used topically as an anti-inflammatory agent for the treatment of skin disorders.
  16. Fenoprofen calcium is used for symptomatic relief for rheumatoid arthritis, osteoarthritis, and mild to moderate pain.
  17. Mometasone furoate is a glucocorticosteroid used topically to reduce inflammation of the skin or in the airways.
  18. Aspartame is a methyl ester of the dipeptide of the natural amino acids L-aspartic acid and L-phenylalanine. Under strongly acidic or alkaline conditions, aspartame may generate methanol by hydrolysis.
  19. Chemically, idebenone is an organic compound of the quinone family. It is also promoted commercially as a synthetic analog of coenzyme Q10 (CoQ10).
  20. Pramiracetam is a nootropic drug derived from piracetam.
  21. Naltrexone is an opioid receptor antagonist used primarily in the management of alcohol dependence and opioid dependence.
  22. Geniposide is an iridoid glycoside with a variety of biological activities including neuroprotective, anti-diabetic, antiproliferative, and antioxidative activity.
  23. Atracurium besylate is a neuromuscular blocking agent with ED95 of 0.2 mg/kg.
  24. Amidopyrine is white crystalline substance used as an analgesic and antipyretic.
  25. Azacyclonol, also known as γ-pipradol, is a drug used to diminish hallucinations in psychotic individuals.
  26. Articaine is a dental local anesthetic which contains an additional ester group that is metabolized by estearases in blood and tissue.
  27. Altrenogest is a progestogen structurally related to veterinary steroid trenbolone.
  28. MCP inhibitor

    Bindarit is an anti-inflammatory small molecule that modulates the NFκB pathway.
  29. Fenticonazole nitrate is an azole antifungal agent.
  30. Ibandronate sodium is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.
  31. Levosimendan is a Ca2+ sensitizer that increases contractile force of the myocardium by enhancing the sensitivity of myofilaments to calcium without increasing intracellular calcium concentration.
  32. Nadifloxacin is a cell-permeable, synthetic, broad-spectrum fluoroquinolone antibiotic that inhibits the growth of both gram-positive and gram-negative microbes.
  33. Pyridoxine hydrochloride is a form of vitamin B6.
  34. Pidotimod is an immunostimulant.
  35. Moxalactam is a synthetically derived, structurally unique beta-lactam antibiotic. Its antimicrobial activity encompasses a wide spectrum and includes some strains of pseudomonal species.
  36. Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond.
  37. Carnosic acid is a diterpene compound exhibiting antioxidative, anticancer, anti-angiogenic, anti-inflammatory, anti-metabolic disorder, and hepatoprotective and neuroprotective activities.
  38. FUBP1 inhibitor

    FUBP1-CIN-1 is a potent FUSE binding protein 1 (FUBP1) inhibitor which interferes with the binding of FUBP1 to its single stranded target DNA FUSE sequence , with an IC50 value of 11.0 μM.
  39. GR antagonist

    AL082D06 is a nonsteroidal glucocorticoid receptor antagonist.
  40. PK14105 is a biological evaluation as a potential radioligand for PET studies of PBBS receptors.
  41. L-Threonine derivative-1 is a acetylsalicylic-L-threonine ester extracted from patent US 20060287244 A1.
  42. Butylphthalide is an antioxidant and one of the chemical constituents in celery oil, along with sedanolide, which is primarily responsible for the aroma and taste of celery.
  43. N-563 is an analogue of deoxyspergualin with an immunostimulating activity,it promotes resistance to Candida albicans infection in mice.
  44. non-narcotic analgesic agent

    W-2429 is a non-narcotic analgesic agent.
  45. Mad2 inhibitor

    M2I-1 is a Mad2 inhibitor targeting the binding of Mad2 to Cdc20, an essential protein-protein interaction (PPI) within the spindle assembly checkpoint (SAC).

Items 101-150 of 980

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