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E(c(RGDfK))2

Catalog No.: A57433
Peptides
E(c(RGDfK))2 is an αvβ3 integrin-specific binding peptide, designed for targeted therapy in oncology research. This agent demonstrates enhanced uptake in human ovarian cancer OVCAR-3 xenograft tumors, making it a valuable tool for studying tumor localization and targeting strategies in cancer treatment. Its specificity for integrin receptors facilitates investigations into tumor biology and the development of targeted therapies.
E(c(RGDfK))2 250612-47-6 Peptides
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Size Price Stock Qty
5mg
$245.00
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10mg
$380.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionE(c(RGDfK))2 is an αvβ3 integrin-specific binding peptide, designed for targeted therapy in oncology research. This agent demonstrates enhanced uptake in human ovarian cancer OVCAR-3 xenograft tumors, making it a valuable tool for studying tumor localization and targeting strategies in cancer treatment. Its specificity for integrin receptors facilitates investigations into tumor biology and the development of targeted therapies.
Product Information
Catalog NumA57433
FormulaC59H87N19O16
Molecular Weight1318.44
CAS Number250612-47-6
SequenceGlu[cyclo(Arg-Gly-Asp-{d-Phe}-Lys)]-cyclo(Arg-Gly-Asp-{d-Phe}-Lys)
Sequence shorteningE[cyclo(RGD-{d-Phe}-K)]-cyclo(RGD-{d-Phe}-K)
SMILESC([C@@H]1C(=O)N[C@@H](CCCCNC([C@H](CCC(NCCCC[C@@H]2NC(=O)[C@@H](CC3=CC=CC=C3)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC2=O)=O)N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N1)C4=CC=CC=C4
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