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P160 peptide

Catalog No.: A54963
Breast Cancer Targeting Peptide
P160 peptide is a breast cancer-targeting peptide that specifically binds to the keratin 1 (KRT1) receptor on breast cancer cells, exhibiting a dissociation constant (Kd) of approximately 1.1 μM. This peptide markedly enhances the cellular uptake and pro-apoptotic activity of the antimicrobial peptide MccJ25 (microcin J25). P160 peptide serves as a valuable tool in cancer research, facilitating targeted drug delivery and improving therapeutic efficacy in breast cancer models.
P160 peptide 362043-77-4 Breast Cancer Targeting Peptide
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionP160 peptide is a breast cancer-targeting peptide that specifically binds to the keratin 1 (KRT1) receptor on breast cancer cells, exhibiting a dissociation constant (Kd) of approximately 1.1 μM. This peptide markedly enhances the cellular uptake and pro-apoptotic activity of the antimicrobial peptide MccJ25 (microcin J25). P160 peptide serves as a valuable tool in cancer research, facilitating targeted drug delivery and improving therapeutic efficacy in breast cancer models.
Product Information
Catalog NumA54963
FormulaC74H105N17O17S
Molecular Weight1536.79
CAS Number362043-77-4
SequenceVal-Pro-Trp-Met-Glu-Pro-Ala-Tyr-Gln-Arg-Phe-Leu
Sequence shorteningVPWMEPAYQRFL
SMILESC([C@H](NC(=O)[C@H]1N(C([C@H](C(C)C)N)=O)CCC1)C(N[C@H](C(N[C@H](C(=O)N2[C@H](C(N[C@H](C(N[C@@H](CC3=CC=C(O)C=C3)C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)=O)C)=O)CCC2)CCC(O)=O)=O)CCSC)=O)C=5C=6C(NC5)=CC=CC6
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