Decapeptide-12

Catalog No.: A56980
Tyrosinase Inhibitor
Decapeptide-12 is a selective inhibitor of tyrosinase, exhibiting a Kd of 61.1 μM and acting as a competitive inhibitor with an IC50 of 40 μM against mushroom tyrosinase. This decapeptide enhances the transcription of SIRT and effectively reduces melanin content in melanocytes. Decapeptide-12 is valuable for research involving melanogenesis, cellular senescence, and inflammation.
Grouped product items
Size Price Stock Qty
10mg
$30.00
In stock
25mg
$55.00
In stock
50mg
$90.00
In stock
100mg
$145.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDecapeptide-12 is a selective inhibitor of tyrosinase, exhibiting a Kd of 61.1 μM and acting as a competitive inhibitor with an IC50 of 40 μM against mushroom tyrosinase. This decapeptide enhances the transcription of SIRT and effectively reduces melanin content in melanocytes. Decapeptide-12 is valuable for research involving melanogenesis, cellular senescence, and inflammation.
Product Information
Catalog NumA56980
FormulaKS3WY3
Molecular Weight1395.52
CAS Number137665-91-9
Sequence shorteningYRSRKYSSWY
SMILESC([C@@H](C(N[C@@H](CC1=CC=C(O)C=C1)C(O)=O)=O)NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=C(O)C=C3)N)=O)CCCNC(=N)N)=O)CO)=O)CCCNC(=N)N)=O)CCCCN)=O)=O)CO)=O)CO)=O)C=4C=5C(NC4)=CC=CC5
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