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MANS peptide

Catalog No.: A57574
MARCKS Inhibitor
MANS peptide is an inhibitor of myristoylated alanine-rich C kinase substrate (MARCKS), which functions by competing with MARCKS for membrane binding in cellular environments. This competitive inhibition effectively reduces the stimulation of mucin secretion and can impede processes related to tumor metastasis. MANS peptide is valuable for research investigating cellular signaling pathways and the role of MARCKS in cancer progression.
MANS peptide 479482-23-0 MARCKS Inhibitor
Grouped product items
Size Price Stock Qty
1mg
$130.00
In stock
5mg
$345.00
In stock
10mg
$590.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMANS peptide is an inhibitor of myristoylated alanine-rich C kinase substrate (MARCKS), which functions by competing with MARCKS for membrane binding in cellular environments. This competitive inhibition effectively reduces the stimulation of mucin secretion and can impede processes related to tumor metastasis. MANS peptide is valuable for research investigating cellular signaling pathways and the role of MARCKS in cancer progression.
Product Information
Catalog NumA57574
FormulaC111H184N30O35
Molecular Weight2498.83
CAS Number479482-23-0
Sequence{Myristic acid-Gly}-Ala-Gln-Phe-Ser-Lys-Thr-Ala-Ala-Lys-Gly-Glu-Ala-Ala-Ala-Glu-Arg-Pro-Gly-Glu-Ala-Ala-Val-Ala
Sequence shortening{Myristic acid-Gly}-AQFSKTAAKGEAAAERPGEAAVA
SMILESC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@@H](NC(CNC(CCCCCCCCCCCCC)=O)=O)C)=O)CCC(N)=O)=O)=O)CO)=O)CCCCN)=O)[C@@H](C)O)=O)C)=O)C)=O)CCCCN)=O)=O)CCC(O)=O)=O)C)=O)C)=O)C)=O)CCC(O)=O)=O)CCCNC(=N)N)(=O)N2[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)C)=O)[C@H](C)C)=O)C)=O)C)=O)CCC(O)=O)=O)=O)CCC2
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