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Kemptamide

Catalog No.: A57603
Peptide Substrate of MLCK
Kemptamide is a peptide substrate for myosin light-chain kinase (MLCK), comprised of a 13 amino acid sequence corresponding to residues 11-23 of gizzard light chain. This compound plays a crucial role in studies investigating MLCK activity and myosin phosphorylation. Its applications include exploring muscle contraction mechanisms and intracellular signaling pathways relevant to various physiological and pathological conditions.
Kemptamide 89315-28-6 Peptide Substrate of MLCK
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionKemptamide is a peptide substrate for myosin light-chain kinase (MLCK), comprised of a 13 amino acid sequence corresponding to residues 11-23 of gizzard light chain. This compound plays a crucial role in studies investigating MLCK activity and myosin phosphorylation. Its applications include exploring muscle contraction mechanisms and intracellular signaling pathways relevant to various physiological and pathological conditions.
Product Information
Catalog NumA57603
FormulaC65H112N24O18
Molecular Weight1517.73
CAS Number89315-28-6
Sequence shorteningKKRPQRATSNVFS-NH2
SMILESC([C@@H](NC([C@@H](NC([C@H](CCCCN)N)=O)CCCCN)=O)CCCNC(=N)N)(=O)N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(N)=O)CO)=O)=O)C(C)C)=O)CC(N)=O)=O)CO)=O)[C@@H](C)O)=O)C)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CCC1
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