CREKA peptide is a self-assembling peptide that selectively binds to fibrin, type IV collagen, and fibronectin. This peptide is utilized as a targeting ligand for modifying delivery carriers, facilitating the accumulation of therapeutic agents in tumor microenvironments and fibrotic tissues. By promoting drug internalization into specific target cells, such as cancer cells and activated hepatic stellate cells, CREKA peptide enhances targeted delivery efficiency, increasing local drug concentration while minimizing systemic side effects.
CREKA peptide is a self-assembling peptide that selectively binds to fibrin, type IV collagen, and fibronectin. This peptide is utilized as a targeting ligand for modifying delivery carriers, facilitating the accumulation of therapeutic agents in tumor microenvironments and fibrotic tissues. By promoting drug internalization into specific target cells, such as cancer cells and activated hepatic stellate cells, CREKA peptide enhances targeted delivery efficiency, increasing local drug concentration while minimizing systemic side effects.
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