β-Amyloid (1-17)

Catalog No.: A78393
β-Amyloid Peptide Fragment
β-Amyloid (1-17) is a peptide fragment of β-Amyloid that is involved in the stabilization of amyloid fibrils. This fragment plays a crucial role in the formation and aggregation of amyloid-beta aggregates, which are implicated in neurodegenerative diseases such as Alzheimer's. Research applications include studies on amyloid fibril behavior and the investigation of β-Amyloid's role in neural pathologies.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptionβ-Amyloid (1-17) is a peptide fragment of β-Amyloid that is involved in the stabilization of amyloid fibrils. This fragment plays a crucial role in the formation and aggregation of amyloid-beta aggregates, which are implicated in neurodegenerative diseases such as Alzheimer's. Research applications include studies on amyloid fibril behavior and the investigation of β-Amyloid's role in neural pathologies.
Product Information
Catalog NumA78393
FormulaC90H130N28O29
Molecular Weight2068.20
CAS Number186319-72-2
SequenceAsp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu
Sequence shorteningDAEFRHDSGYEVHHQKL
SMILES[C@@H](CC1=CN=CN1)(NC([C@H](CC2=CN=CN2)NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=C(O)C=C3)NC(CNC([C@@H](NC([C@@H](NC([C@H](CC4=CN=CN4)NC([C@@H](NC([C@H](CC5=CC=CC=C5)NC([C@@H](NC([C@@H](NC([C@H](CC(O)=O)N)=O)C)=O)CCC(O)=O)=O)=O)CCCNC(=N)N)=O)=O)CC(O)=O)=O)CO)=O)=O)=O)CCC(O)=O)=O)C(C)C)=O)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)CCCCN)=O)CCC(N)=O)=O
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