Scrambled β-amyloid (1-40)

Catalog No.: A78401
Bioactive Peptide
Scrambled β-amyloid (1-40) is a bioactive peptide that functions as a structural variant of the β-amyloid protein. This peptide mimics the assembly characteristics of the major C-terminal variants Aβ (1-40) and Aβ (1-42), both of which contribute to amyloid plaque formation in Alzheimer's disease. Research applications include the study of amyloid aggregation processes and examination of peptide interactions within neurodegenerative contexts.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionScrambled β-amyloid (1-40) is a bioactive peptide that functions as a structural variant of the β-amyloid protein. This peptide mimics the assembly characteristics of the major C-terminal variants Aβ (1-40) and Aβ (1-42), both of which contribute to amyloid plaque formation in Alzheimer's disease. Research applications include the study of amyloid aggregation processes and examination of peptide interactions within neurodegenerative contexts.
Product Information
Catalog NumA78401
FormulaC194H295N53O58S
Molecular Weight4329.80
CAS Number1678415-68-3
SequenceAla-Glu-Gly-Asp-Ser-His-Val-Leu-Lys-Glu-Gly-Ala-Tyr-Met-Glu-Ile-Phe-Asp-Val-Gln-Gly-His-Val-Phe-Gly-Gly-Lys-Ile-Phe-Arg-Val-Val-Asp-Leu-Gly-Ser-His-Asn-Val-Ala
Sequence shorteningAEGDSHVLKEGAYMEIFDVQGHVFGGKIFRVVDLGSHNVA
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