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CaMKII inhibitory peptide KIIN

Catalog No.: A78521
CaMKII Inhibitor
CaMKII inhibitory peptide KIIN is a selective inhibitor of calcium/calmodulin-dependent protein kinase II (CaMKII). This peptide effectively disrupts CaMKII activity, making it a valuable tool for studying CaMKII-dependent signaling pathways. Its use in various research applications includes investigating cellular processes such as synaptic plasticity, memory formation, and cardiac function.
CaMKII inhibitory peptide KIIN 508181-45-1 CaMKII Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCaMKII inhibitory peptide KIIN is a selective inhibitor of calcium/calmodulin-dependent protein kinase II (CaMKII). This peptide effectively disrupts CaMKII activity, making it a valuable tool for studying CaMKII-dependent signaling pathways. Its use in various research applications includes investigating cellular processes such as synaptic plasticity, memory formation, and cardiac function.
Product Information
Catalog NumA78521
FormulaC136H240N44O39
Molecular Weight3115.63
CAS Number508181-45-1
SequenceLys-Arg-Pro-Pro-Lys-Leu-Gly-Gln-Ile-Gly-Arg-Ala-Lys-Arg-Val-Val-Ile-Glu-Asp-Asp-Arg-Ile-Asp-Asp-Val-Leu-Lys
Sequence shorteningKRPPKLGQIGRAKRVVIEDDRIDDVLK
SMILESC(=O)([C@H]1N(C([C@@H](NC([C@H](CCCCN)N)=O)CCCNC(=N)N)=O)CCC1)N2[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCCN)C(O)=O)=O)CC(C)C)=O)C(C)C)=O)CC(O)=O)=O)CC(O)=O)=O)[C@H](CC)C)=O)CCCNC(=N)N)=O)CC(O)=O)=O)CC(O)=O)=O)CCC(O)=O)=O)[C@H](CC)C)=O)[C@H](C)C)=O)C(C)C)=O)CCCNC(=N)N)=O)CCCCN)=O)C)=O)CCCNC(=N)N)=O)=O)[C@H](CC)C)=O)CCC(N)=O)=O)=O)CC(C)C)=O)CCCCN)=O)CCC2
SynonymsCalmodulin Kinase IINtide; CaM-KIIN; CaM-KIINβ
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