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Activated Protein C (390-404), human

Catalog No.: A77667
Polypeptide
Activated Protein C (390-404), human is a polypeptide fragment derived from the vitamin K-dependent serine protease activated protein C (APC). This fragment specifically inhibits the anticoagulant function of APC by blocking its ability to inactivate factor Va. It serves as a valuable tool in studies of coagulation pathways and the regulation of anticoagulant mechanisms, contributing to research in thrombosis and hemostasis.
Activated Protein C (390-404), human 146340-20-7 Polypeptide
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Size Price Stock Qty
1mg
$160.00
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5mg
$285.00
In stock
10mg
$470.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionActivated Protein C (390-404), human is a polypeptide fragment derived from the vitamin K-dependent serine protease activated protein C (APC). This fragment specifically inhibits the anticoagulant function of APC by blocking its ability to inactivate factor Va. It serves as a valuable tool in studies of coagulation pathways and the regulation of anticoagulant mechanisms, contributing to research in thrombosis and hemostasis.
Product Information
Catalog NumA77667
FormulaC91H130N22O23
Molecular Weight1900.14
CAS Number146340-20-7
SequenceTyr-Gly-Val-Tyr-Thr-Lys-Val-Ser-Arg-Tyr-Leu-Asp-Trp-Ile-His
Sequence shorteningYGVYTKVSRYLDWIH
SMILESC([C@@H](C(N[C@H](C(N[C@@H](CC1=CN=CN1)C(O)=O)=O)[C@H](CC)C)=O)NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=C(O)C=C3)NC([C@@H](NC(CNC([C@H](CC4=CC=C(O)C=C4)N)=O)=O)C(C)C)=O)=O)[C@@H](C)O)=O)CCCCN)=O)[C@H](C)C)=O)CO)=O)CCCNC(=N)N)=O)=O)CC(C)C)=O)CC(O)=O)=O)C=5C=6C(NC5)=CC=CC6
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