SP-10

Catalog No.: A78700
Small Peptides
SP-10 is a small peptide that specifically targets the interaction between the spike (S) protein of SARS-CoV and the angiotensin-converting enzyme 2 (ACE2) receptor, exhibiting an IC50 value of 1.88 nM. This compound is valuable for research on SARS-CoV, particularly in studies investigating viral entry mechanisms and the development of therapeutic agents aimed at inhibiting this critical interaction. Its potent activity makes it an essential tool for exploring antiviral strategies.
Grouped product items
Size Price Stock Qty
1mg
$520.00
In stock
Bulk Size
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSP-10 is a small peptide that specifically targets the interaction between the spike (S) protein of SARS-CoV and the angiotensin-converting enzyme 2 (ACE2) receptor, exhibiting an IC50 value of 1.88 nM. This compound is valuable for research on SARS-CoV, particularly in studies investigating viral entry mechanisms and the development of therapeutic agents aimed at inhibiting this critical interaction. Its potent activity makes it an essential tool for exploring antiviral strategies.
Product Information
Catalog NumA78700
FormulaC56H94N14O20S
Molecular Weight1315.49
CAS Number882157-88-2
SequenceSer-Thr-Ser-Gln-Lys-Ser-Ile-Val-Ala-Tyr-Thr-Met
Sequence shorteningSTSQKSIVAYTM
SMILESCC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H](N)CO)[C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCSC)C(O)=O |@@:53|
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