β Amyloid (1-16) rat

Catalog No.: A78408
β-amyloid Peptide
β-Amyloid (1-16) rat is a fragment of the β-amyloid peptide (Aβ) featuring a metal-binding domain. This synthetic peptide contains three amino acid substitutions that make it distinct from the human form, resulting in reduced susceptibility to amyloid-related neurodegeneration in rodent models. It is primarily utilized in research applications focused on Alzheimer's disease mechanisms and the study of amyloid pathology.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptionβ-Amyloid (1-16) rat is a fragment of the β-amyloid peptide (Aβ) featuring a metal-binding domain. This synthetic peptide contains three amino acid substitutions that make it distinct from the human form, resulting in reduced susceptibility to amyloid-related neurodegeneration in rodent models. It is primarily utilized in research applications focused on Alzheimer's disease mechanisms and the study of amyloid pathology.
Product Information
Catalog NumA78408
FormulaC80H115N25O27
Molecular Weight1858.92
CAS Number1123154-43-7
SequenceAsp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Glu-Val-Arg-His-Gln-Lys
Sequence shorteningDAEFGHDSGFEVRHQK
SMILES[C@@H](CC1=CN=CN1)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=CC=C2)NC(CNC([C@@H](NC([C@@H](NC([C@H](CC3=CN=CN3)NC(CNC([C@H](CC4=CC=CC=C4)NC([C@@H](NC([C@@H](NC([C@H](CC(O)=O)N)=O)C)=O)CCC(O)=O)=O)=O)=O)=O)CC(O)=O)=O)CO)=O)=O)=O)CCC(O)=O)=O)[C@@H](C)C)=O)CCCNC(=N)N)=O)C(N[C@H](C(N[C@@H](CCCCN)C(O)=O)=O)CCC(N)=O)=O
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