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Hirudin (55-65) sulfated

Catalog No.: A77921
Polypeptide
Hirudin (55-65) sulfated is a polypeptide fragment that acts as a potent inhibitor of thrombin, demonstrating significant anticoagulant properties. This compound is essential for studies related to coagulation pathways and thrombin-mediated physiological processes. Its applications extend to the investigation of antithrombotic therapies and the development of pharmacological agents targeting blood coagulation disorders.
Hirudin (55-65) sulfated 109528-50-9 Polypeptide
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionHirudin (55-65) sulfated is a polypeptide fragment that acts as a potent inhibitor of thrombin, demonstrating significant anticoagulant properties. This compound is essential for studies related to coagulation pathways and thrombin-mediated physiological processes. Its applications extend to the investigation of antithrombotic therapies and the development of pharmacological agents targeting blood coagulation disorders.
Product Information
Catalog NumA77921
FormulaC64H90N12O27S
Molecular Weight1491.53
CAS Number109528-50-9
SequenceH-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr(SO3H)-Leu-Gln-OH
Sequence shorteningDFEEIPEE-{Y(SO3H)}-LQ
SMILESC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@H](CC(O)=O)N)=O)=O)CCC(O)=O)=O)CCC(O)=O)=O)[C@H](CC)C)(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=C(OS(=O)(=O)O)C=C3)C(N[C@H](C(N[C@@H](CCC(N)=O)C(O)=O)=O)CC(C)C)=O)=O)CCC(O)=O)=O)CCC(O)=O)=O)CCC2
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