NYLTHRQ

Catalog No.: A34783
Peptide
NYLTHRQ is a peptide that specifically disrupts the interaction between soluble VEGFR1 isoform i13 and β1 integrin, leading to the inhibition of VEGFR1 and VEGFR2 activation. This modulation results in a reduction of cancer cell proliferation, highlighting its potential in cancer therapeutics. NYLTHRQ is particularly relevant for research focused on tumors, including lung squamous cell carcinoma.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionNYLTHRQ is a peptide that specifically disrupts the interaction between soluble VEGFR1 isoform i13 and β1 integrin, leading to the inhibition of VEGFR1 and VEGFR2 activation. This modulation results in a reduction of cancer cell proliferation, highlighting its potential in cancer therapeutics. NYLTHRQ is particularly relevant for research focused on tumors, including lung squamous cell carcinoma.
Product Information
Catalog NumA34783
FormulaC40H62N14O12
Molecular Weight931.01
CAS Number1004284-41-6
SequenceAsn-Tyr-Leu-Thr-His-Arg-Gln
Sequence shorteningNYLTHRQ
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