KLTWQELYQLKYKGI

Catalog No.: A34728
Proangiogenic Peptide
KLTWQELYQLKYKGI is a proangiogenic peptide designed to mimic vascular endothelial growth factor (VEGF) and activate VEGF receptors. This peptide significantly enhances the attachment, spreading, and proliferation of human umbilical vein endothelial cells, as well as promoting the proliferation, migration, and osteogenic differentiation of bone marrow stromal cells (BMSCs). KLTWQELYQLKYKGI has demonstrated synergistic effects in accelerating angiogenesis and bone regeneration in rat cranial defect models, making it valuable for applications in brain tissue engineering, traumatic brain injury repair, and bone tissue engineering.
Grouped product items
Size Price Stock Qty
5mg
$70.00
In stock
10mg
$120.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionKLTWQELYQLKYKGI is a proangiogenic peptide designed to mimic vascular endothelial growth factor (VEGF) and activate VEGF receptors. This peptide significantly enhances the attachment, spreading, and proliferation of human umbilical vein endothelial cells, as well as promoting the proliferation, migration, and osteogenic differentiation of bone marrow stromal cells (BMSCs). KLTWQELYQLKYKGI has demonstrated synergistic effects in accelerating angiogenesis and bone regeneration in rat cranial defect models, making it valuable for applications in brain tissue engineering, traumatic brain injury repair, and bone tissue engineering.
Product Information
Catalog NumA34728
FormulaC92H143N21O23
Molecular Weight1911.25
CAS Number917760-16-8
SequenceLys-Leu-Thr-Trp-Gln-Glu-Leu-Tyr-Gln-Leu-Lys-Tyr-Lys-Gly-Ile
Sequence shorteningKLTWQELYQLKYKGI
SMILESC([C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=C(O)C=C1)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=C(O)C=C2)C(N[C@H](C(NCC(N[C@@H]([C@H](CC)C)C(O)=O)=O)=O)CCCCN)=O)=O)CCCCN)=O)CC(C)C)=O)CCC(N)=O)=O)=O)CC(C)C)=O)CCC(O)=O)=O)CCC(N)=O)=O)NC([C@@H](NC([C@@H](NC([C@H](CCCCN)N)=O)CC(C)C)=O)[C@@H](C)O)=O)C=3C=4C(NC3)=CC=CC4
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