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CK3 peptide

Catalog No.: A35205
NRP-1 Targeting Peptide
CK3 peptide is an NRP-1 targeting peptide characterized by the amino acid sequence CLKADKAKC. It selectively binds to NRP-1 on breast cancer cells, facilitating targeted imaging and therapeutic applications. In vivo studies utilizing single-photon emission computed tomography (SPECT) and near-infrared fluorescence (NIRF) imaging demonstrate significant accumulation of CK3 peptide in xenograft tumors within nude mice. This peptide is suitable for molecular imaging research in breast cancer.
CK3 peptide 1801552-75-9 NRP-1 Targeting Peptide
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCK3 peptide is an NRP-1 targeting peptide characterized by the amino acid sequence CLKADKAKC. It selectively binds to NRP-1 on breast cancer cells, facilitating targeted imaging and therapeutic applications. In vivo studies utilizing single-photon emission computed tomography (SPECT) and near-infrared fluorescence (NIRF) imaging demonstrate significant accumulation of CK3 peptide in xenograft tumors within nude mice. This peptide is suitable for molecular imaging research in breast cancer.
Product Information
Catalog NumA35205
FormulaC40H72N12O12S2
Molecular Weight977.20
CAS Number1801552-75-9
SequenceCys-Leu-Lys-Ala-Asp-Lys-Ala-Lys-Cys (disulfide bridge:Cys1-Cys9)
Sequence shorteningCLKADKAKC (disulfide bridge:Cys1-Cys9)
SMILESC(CCCN)[C@@H]1NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CSSC[C@@H](C(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC1=O
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