Lyn peptide inhibitor

Catalog No.: A34911
Lyn Kinase Inhibitor
Lyn Peptide Inhibitor is a selective inhibitor of Lyn kinase that specifically targets the Lyn-coupled IL-5 receptor signaling pathway. This compound effectively blocks Lyn activation and disrupts the interaction between Lyn tyrosine kinase and the βc subunit of IL-3/GM-CSF/IL-5 receptors. The Lyn Peptide Inhibitor is valuable for investigating mechanisms underlying asthma, allergic reactions, and various eosinophilic disorders, providing insights into potential therapeutic approaches.
Grouped product items
Size Price Stock Qty
1mg
$55.00
In stock
5mg
$150.00
In stock
10mg
$245.00
In stock
25mg
$455.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLyn Peptide Inhibitor is a selective inhibitor of Lyn kinase that specifically targets the Lyn-coupled IL-5 receptor signaling pathway. This compound effectively blocks Lyn activation and disrupts the interaction between Lyn tyrosine kinase and the βc subunit of IL-3/GM-CSF/IL-5 receptors. The Lyn Peptide Inhibitor is valuable for investigating mechanisms underlying asthma, allergic reactions, and various eosinophilic disorders, providing insights into potential therapeutic approaches.
Product Information
Catalog NumA34911
FormulaC115H184N30O24
Molecular Weight2370.88
CAS Number222018-18-0
Sequence{Stearoyl}-Tyr-Gly-Tyr-Arg-Leu-Arg-Arg-Lys-Trp-Glu-Glu-Lys-Ile-Pro-Asn-Pro-NH2
Sequence shortening{Stearoyl}-YGYRLRRKWEEKIPNP-NH2
SMILESC([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=C(O)C=C1)NC(CNC([C@H](CC2=CC=C(O)C=C2)NC(CCCCCCCCCCCCCCCCC)=O)=O)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCCN)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N3[C@H](C(N[C@H](C(=O)N4[C@H](C(N)=O)CCC4)CC(N)=O)=O)CCC3)[C@H](CC)C)=O)CCCCN)=O)CCC(O)=O)=O)CCC(O)=O)=O)C=5C=6C(NC5)=CC=CC6
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