Catalog No.
Product Name
Application
Product Information
Citations
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Bactericide
HMR-3787 is a 2-fluoroketolide that functions as a bactericide. It exhibits potent bactericidal activity against multiple strains of Haemophilus influenzae, making it a valuable tool for microbiological research. HMR-3787 is particularly useful for studies focused on bacterial resistance and the development of novel therapeutic agents. -
Bacterial Inhibitor
INF55 is a multidrug resistance pump inhibitor targeting bacterial efflux mechanisms. By inhibiting the NoA pump, INF55 enhances the antibacterial efficacy of compounds such as berberine, reducing their efflux and overcoming bacterial resistance. Structural variants of INF55 demonstrate diverse NoA inhibitory activities, which can influence the antibacterial effectiveness of their respective heterocomplexes. This versatility makes INF55 and its derivatives valuable tools in the study and development of novel antimicrobial strategies. -
Antibacterial Agent
FOL7185 is an antibacterial agent that targets the IspD and IspE enzymes found in bacterial species. This compound exhibits potent inhibitory activity, disrupting critical biochemical pathways involved in bacterial cell wall biosynthesis. FOL7185 is useful for research applications aimed at understanding bacterial resistance mechanisms and developing novel antimicrobial therapies. -
Anti-Bacterial Agent
Pacidamycin 4 is an anti-bacterial agent with a primary mechanism of inhibiting Pseudomonas aeruginosa. It also exhibits activity against several other bacterial strains, including Staphylococcus aureus and Escherichia coli. The antibacterial efficacy of Pacidamycin 4 is influenced by serum and is affected by variations in pH, making it important for researchers to consider these factors in experimental design. This compound is valuable for studies exploring bacterial resistance and the development of novel antimicrobial therapies. -
Anti-Bacterial Agent
Gilvocarcin E is an anti-bacterial agent that primarily targets Gram-positive bacteria. It exhibits significant biological activity against various strains, as well as inhibitory effects on sarcoma 180 and P388 leukemia cells. This compound is valuable for research in microbiology and cancer biology, providing insights into bacterial resistance and potential therapeutic approaches. -
Antibiotic Intermediate
7-APRA is a semi-synthetic intermediate of cephalosporin antibiotics, targeting bacterial cell wall synthesis. It exhibits significant antibacterial activity and serves primarily in the synthesis of other antibiotics, such as Cefaclor and Cefprozil. This compound is valuable in microbiological research and the development of cephalosporin-based therapeutics. -
Anti-Bacterial Agent
Fumaryl-DL-alanine, recognized for its antibacterial properties, primarily targets Gram-positive bacteria. This compound exhibits significant activity against bacterial strains, making it a valuable tool for research in antimicrobial efficacy and mechanism of action studies. Its properties facilitate investigations into bacterial resistance and the development of new antibacterial agents. -
β-Lactamase
ETX1317 is a potent β-lactamase inhibitor designed to restore the antibacterial efficacy of various β-lactam antibiotics, including third-generation cephalosporins like Cefpodoxime. This reagent is ideal for investigating bacterial resistance mechanisms and enhancing the therapeutic effectiveness of β-lactam therapies in research settings focused on bacterial infections. -
Bacterial Inhibitor
Racemomycin B is a potent bacterial inhibitor derived from Streptomyces lavendulae OP-2, characterized as a streptothricin antibiotic with three β-lysine groups. It demonstrates significant antimicrobial activity against plant pathogenic microorganisms, effectively inhibiting the root growth of Brassica rapa L. at a concentration of 50 ppm. Racemomycin B exhibits a minimum inhibitory concentration (MIC) of 0.4 μg/ml against Pseudomonas syringae pv. tabaci IFO-3508 and a MIC range of 0.1-2.0 μg/ml against various strains of Fusarium oxysporum. The biological efficacy of this compound is enhanced by the increasing number of β-lysine groups, making it a valuable tool for agricultural research. -
Anti-Bacterial Agent
Glysperin C is an anti-bacterial agent targeting both Gram-positive and Gram-negative bacteria, including those resistant to aminoglycoside antibiotics. Its broad-spectrum activity makes it a valuable tool for research into bacterial resistance mechanisms and the development of new therapeutic strategies against various infectious diseases. -
Anticancer Agent
Previridicatumtoxin is a fungal metabolite known for its antibacterial and anticancer properties. Derived from the organism P. aethiopicum, this compound demonstrates significant biological activity against cancer cells and has potential applications in cancer research and studies related to infections. Its unique mechanism of action makes it a valuable tool for exploring therapeutic strategies in oncology and microbiology. -
Antibacterial Agent
Octenidine (saccharin) is a potent antibacterial agent that targets multidrug-resistant Gram-negative pathogens. This compound exhibits significant activity by inhibiting the expression of biofilm-associated genes, which disrupts biofilm formation. Its unique properties make it valuable for research applications focused on combating antibiotic resistance and biofilm-related infections. -
Anti-Bacterial Agent
Diatretyne I is an anti-bacterial agent that exhibits selective activity against Gram-positive bacteria. This compound demonstrates potential in addressing bacterial infections and may serve as a valuable tool in microbiological research for evaluating antibacterial efficacy and understanding resistance mechanisms. -
Anti-Bacterial Agent
Galacardin B is an anti-bacterial agent that specifically targets Gram-positive bacteria. It exhibits potent bactericidal activity, making it valuable in research focused on developing treatments for infections caused by resistant bacterial strains. This compound serves as a critical tool for scientists investigating antibacterial mechanisms and therapeutic options in microbiology. -
Antibacterial Agent
Palmitanilide is an antibacterial agent that specifically targets Gram-positive bacteria. It exerts its activity by electrostatically binding to components within the bacterial cell wall, leading to alterations in cell membrane structure and disruption of normal cell functions. This compound shows promise for research applications focused on infectious diseases caused by Gram-positive pathogens, such as Bacillus cereus. -
Anti-Bacterial Agent
Fosfocytocin is an antibacterial agent derived from the strain of Pseudomonas fluorescens PK-52. It exhibits low antibacterial activity, making it a subject of interest for studying bacterial resistance mechanisms. This compound may serve as a valuable tool in research applications focused on antimicrobial peptides and their interactions with bacterial pathogens. -
Anti-Bacterial Agent
Chlorocardicin is a monocyclic beta-lactam antibiotic that primarily targets bacterial cell wall synthesis. It demonstrates moderate in vitro activity against Enterobacteriaceae and Pseudomonas aeruginosa, making it a valuable tool for studying bacterial infections and resistance mechanisms. This compound is applicable in research focused on antibiotic development and evaluating the efficacy of beta-lactam antibiotics. -
Anti-Bacterial Agent
15-Deoxy-15-oxolankamycin is an anti-bacterial agent with a specific mechanism targeting Gram-positive bacteria. This compound exhibits weak antibacterial activity, making it a valuable tool for studying bacterial resistance and the efficacy of antibiotics. Its applications extend to microbiological research, where it can aid in the investigation of bacterial growth and response to various treatments. -
Anti-Bacterial Agent
Ditrisarubicin A is an anti-bacterial agent with demonstrated efficacy against Gram-positive bacteria. In addition to its antibacterial properties, it exhibits cytotoxic effects on L-1210 cells, highlighting its potential in cancer research. This compound can be utilized in studies aimed at understanding bacterial resistance mechanisms and evaluating therapeutic strategies for both bacterial infections and cancer. -
Anti-Bacterial Agent
Oganomycin GB is an antibacterial agent derived from the fermentation of Streptomyces str. oganonensis Y-G 19Z. It exhibits potent activity against both Gram-positive and Gram-negative bacteria, demonstrating stability and efficacy superior to its precursor compounds. Oganomycin GB's mechanism involves the inhibition of D-amino acid oxidase, leading to alterations in metabolic pathways that enhance its antibacterial properties. This reagent is valuable for research in microbiology and antibiotic development. -
Antibacterial Agent
Aldgamycin F is an antibacterial agent that exhibits potent antimicrobial activity through its interaction with bacterial ribosomes, inhibiting protein synthesis. This compound is primarily used in research focused on developing new antibiotics and studying mechanisms of bacterial resistance. Its effectiveness against various bacterial strains makes it a valuable tool in microbiological and pharmaceutical investigations. -
Anti-Bacterial Agent
Cladospolide A is a natural compound derived from the fungus Cladosporium sp. FT-0012, exhibiting potential anti-bacterial properties. Although its antibacterial activity is limited, it serves as a valuable tool for research into microbial interactions and the development of novel antimicrobial strategies. Further studies can explore its specific mechanisms and applications in the field of infectious disease research. -
Antibiotic
Phenelfamycins C is an antibiotic derived from Streptomyces violaceoniger strains AB 9991-80 and AB 1047T-33. Its primary mechanism involves targeting and inhibiting the growth of eutrophic bacteria, demonstrating notable antibacterial activity. This compound is valuable for research applications focused on antibiotic development and studies of bacterial resistance mechanisms. -
Bacterial Inhibitor
(R,R)-Ethambutol is a bacterial inhibitor primarily targeting Mycobacterium tuberculosis, exhibiting significant antituberculosis activity. It is commonly utilized in combination therapies to enhance the therapeutic efficacy against tuberculosis. Additionally, (R,R)-Ethambutol demonstrates effectiveness in inhibiting infections caused by Mycobacterium avium complex and Mycobacterium kansasii, making it a valuable reagent for research in mycobacterial infections. -
Bacterial Regulator
N-Pentadecanoyl-L-homoserine lactone is an N-acyl homoserine lactone that functions as a bacterial regulator. It acts as a signaling molecule involved in quorum sensing, enabling bacteria to coordinate group behaviors based on population density. This compound is utilized in research to study bacterial communication and the regulation of virulence factors, offering insights into microbial pathogenesis and potential therapeutic interventions. -
Bacterial Mutagenic Compound
Catalpin is an iridoid compound derived from Catalpae Fructus, known for its mutagenic activity. It exhibits significant mutagenicity towards the Salmonella typhimurium strain TA100, making it a valuable reagent for studying bacterial mutation mechanisms. This compound is useful in research applications focused on mutagenesis and the assessment of genetic variations induced by environmental factors. -
Anti-Bacterial Agent
Istamycin B is an anti-bacterial agent that demonstrates potent activity against both Gram-positive and Gram-negative bacteria. Its mechanism of action involves disrupting bacterial cell wall synthesis, leading to cell lysis and death. This compound is valuable for research applications focusing on developing new antibiotics and understanding bacterial resistance mechanisms. -
Anti-Bacterial Agent
Cephamycin B is a β-lactam antibiotic that exerts its antibacterial effects by inhibiting bacterial cell wall synthesis. It demonstrates moderate activity against both Gram-positive and Gram-negative bacteria. This compound is particularly useful in microbiological research for studying antibiotic resistance and bacterial growth dynamics. -
Antibacterial Agent
K13787 is an acetohydroxyacid synthase (AHAS) inhibitor that exhibits antibacterial activity. This compound demonstrates efficacy against a range of nontuberculous mycobacteria (NTM) and strains resistant to clarithromycin. K13787 is valuable for research involving antibacterial resistance mechanisms and the development of new therapeutic agents targeting mycobacterial infections. -
Antimycobacterial Agent
Antitubercular agent-57 is a selective antimycobacterial agent targeting Mycobacterium tuberculosis. It demonstrates significant efficacy against both drug-sensitive and multidrug-resistant strains, including extensively drug-resistant variants, while maintaining low toxicity towards mammalian cell lines, such as hepatocytes. Antitubercular agent-57 exhibits no cross-resistance with established first and second-line antitubercular agents and shows no antimicrobial activity against Gram-positive and Gram-negative bacteria or fungal strains. This reagent is valuable for research focused on tuberculosis and multidrug-resistant tuberculosis. -
Anti-Bacterial Agent
Chrysospermin A is an antibacterial agent with demonstrated activity against various Gram-positive bacteria, including Staphylococcus aureus and Bacillus subtilis, as well as against Klebsiella pneumoniae. Additionally, it exhibits inhibitory effects on individual yeast species such as Ocher echinoderma and Saccharomyces cerevisiae. This compound is valuable for research applications focused on the development of antibacterial therapies and the study of antimicrobial resistance. -
Antibacterial Agent
LL-BM123γ2 is an antibacterial agent that exhibits activity against a broad spectrum of microorganisms. Its efficacy makes it suitable for research applications focused on understanding antibacterial mechanisms and developing new therapeutic strategies. -
Anti-Bacterial Agent
Cinerubin R is an anti-bacterial agent that exhibits potent activity against Gram-positive bacteria. Additionally, it demonstrates inhibitory effects on tumor cell proliferation and is effective against multidrug-resistant (MDR) cells, displaying similar inhibitory potency to protocells. This compound is valuable for research in antibacterial therapies and cancer treatment strategies. -
Anti-Bacterial Agent
Basidalin is an anti-bacterial agent exhibiting activity against both Gram-positive and Gram-negative bacteria. It has demonstrated efficacy in inhibiting the proliferation of mouse leukemia L-1210 cells, making it a valuable tool for research in microbiology and oncology. Its broad-spectrum antibacterial properties and potential antitumor activity support various applications in experimental studies related to infectious diseases and cancer research. -
Anti-Bacterial Agent
Ochracenomicin C is an antibacterial agent derived from the strain Amicolatopsis sp. MJ 950-891. It exhibits moderate antibacterial activity, demonstrating potential utility in studying antibiotic resistance and the mechanisms of bacterial growth inhibition. This compound may serve as a valuable tool in research focused on developing new antibacterial strategies. -
Anti-Bacterial Agent
Ilicicolin B is a potent anti-bacterial agent that specifically inhibits Bacillus carbonifera at a concentration of 6 μg/mL. Its selectivity is highlighted by a toxic concentration of 0.3 μg/mL in HeLa cells. This compound is valuable for research on bacterial infections and the study of bacterial resistance mechanisms. -
Anti-Bacterial Agent
Cinnatriacetin B is a natural compound derived from the fungus Fistulina hepatica, primarily exhibiting anti-bacterial activity against Gram-positive bacteria. Its unique mechanism of action makes it a valuable agent for studying bacterial inhibition and resistance mechanisms. Cinnatriacetin B is applicable in microbiological research and offers potential insights into the development of novel antibacterial therapies. -
Anti-Bacterial Agent
Dactylocycline E is an anti-bacterial agent that exhibits activity against Gram-positive bacteria. This compound is particularly valuable in the study of bacterial infections and the development of novel antimicrobial therapies. Its mechanism of action involves inhibition of bacterial protein synthesis, making it an important tool in microbiological research. -
Anti-Bacterial Agent
Fenbenicillin potassium is a semi-synthetic penicillin that targets bacterial cell wall synthesis. It exhibits potent antibacterial activity against a range of Gram-positive and certain Gram-negative bacteria. This reagent is primarily utilized in microbiological research to study bacterial infections and antibiotic resistance mechanisms. -
Anti-Bacterial Agent
Coriolin B is an anti-bacterial agent that exhibits significant activity against Gram-positive bacteria, as well as limited efficacy against Gram-negative bacteria and yeast. At a concentration of 5 μg/mL, Coriolin B demonstrates an inhibitory effect on the growth of Yoshida sarcoma by 61.6%. Notably, it shows no inhibitory effect on Ehrlich ascites carcinoma in animal models, highlighting its selective action. This compound is useful for research applications focused on antimicrobial activity and cancer biology. -
Antibacterial Peptide
Albonoursin is an antibacterial peptide derived from microbial secondary metabolites, primarily targeting bacterial cell membranes. This compound exhibits significant antibacterial activity against a range of pathogenic organisms and shows potential for antitumor activity as well. Albonoursin is valuable in research focused on antibiotic development and cancer therapeutics. -
β-lactamase Inhibitor
CB-618 is a β-lactamase inhibitor that reversibly covalently interacts with Ambler class A, C, and select class D serine β-lactamases. While it exhibits limited antibacterial activity on its own, CB-618 notably enhances the effectiveness of Meropenem against enzyme-producing Enterobacteriaceae. This compound is a valuable tool for research focused on combating drug-resistant bacterial strains. -
Anti-Bacterial Agent
Curromycin A is an antibacterial agent primarily targeting Gram-positive bacteria, including Bacillus subtilis. It exhibits notable antibacterial activity and has demonstrated the ability to inhibit the replication of human immunodeficiency virus (HIV). Additionally, Curromycin A has shown efficacy against mouse melanoma B16 and leukemia P388 cell lines, making it a useful reagent for various biological research applications. -
Anti-Bacterial Agent
Cepacin B is an anti-bacterial agent that exhibits activity against both Gram-positive and Gram-negative bacteria. This compound can be utilized in various research applications focused on bacterial inhibition and antibiotic development. Its broad-spectrum efficacy makes it a valuable tool in microbiological studies. -
β-Lactamase Inhibitor
LN-1-255 sodium is a β-lactamase inhibitor designed to effectively combat resistance in bacteria. It exhibits a broad-spectrum inhibitory effect on type D carbapenemases, demonstrating an IC50 of 3 nM against OXA-48, while also showing strong activity against OXA-23 and OXA-24/40. The compound enhances the efficacy of carbapenem antibiotics through a synergistic mechanism. LN-1-255 sodium is a valuable tool for researching the challenges posed by carbapenem-hydrolyzing class D β-lactamases (CHDLs) in bacterial resistance. -
Antibacterial Agent
LY 255262 is an antibacterial agent that demonstrates potent inhibitory activity against a range of Gram-positive and Gram-negative bacteria. In vitro studies reveal minimum inhibitory concentration (MIC) values of 64 μg/mL for Staphylococcus aureus, 0.25 μg/mL for Streptococcus pneumoniae, and 0.5 μg/mL for Haemophilus influenzae, among others. Notably, LY 255262 exhibits a reduced effect on Pseudomonas species with an MIC greater than 128 μg/mL. This compound is suitable for applications in antibacterial research. -
Antibacterial Agent
Antibacterial Agent 174 targets bacterial infections through its potent anti-infective properties. This compound exhibits significant efficacy in vivo, demonstrating favorable pharmacokinetic profiles. Antibacterial Agent 174 is particularly effective in biofilm removal, while exhibiting low hemolytic activity and acceptable toxicity towards mammalian cells, making it a valuable tool for research on bacterial infections and treatment strategies. -
Anti-Bacterial Agent
Oleficin is an anti-bacterial agent that demonstrates resistance to Gram-positive bacteria. This compound has shown effectiveness in preclinical models, particularly in addressing subcutaneous transplantation of Yoshida sarcoma. Its biological activity makes it a valuable tool for research in infectious diseases and tumor biology. -
Anti-Bacterial Agent
Paulomenol A is an antibacterial agent that exhibits potent activity against Gram-positive bacteria, including Staphylococcus aureus, Streptococcus pyogenes, and Streptococcus pneumoniae. This compound is of significant interest for research applications aimed at combating bacterial infections and exploring new therapeutic strategies in antimicrobial drug development. Its effectiveness in inhibiting the growth of these pathogens makes it a valuable tool for investigating antibacterial mechanisms and resistance. -
Bacterial Metabolite
Ilicicolin F is a fungal metabolite that primarily targets bacterial oxidases, specifically inhibiting T. vivax alternative oxidase and E. coli ubiquinol oxidase cytochrome bo, with IC50 values of 0.43 and 0.37 μM, respectively. It exhibits antifungal activity against Aspergillus fumigatus and Candida albicans, demonstrating minimum inhibitory concentrations ranging from 1.66 to 13.33 μg/mL. Additionally, Ilicicolin F displays significant cytotoxicity in HeLa cells, with an EC50 value of 0.003 μg/mL, making it a potent candidate for research in microbial and cancer studies.
