Catalog No.
Product Name
Application
Product Information
Citations
-
Sulfonamide Antibacterial
Sulfamerazine-d4 is a deuterated form of sulfamerazine, a sulfonamide antibacterial agent. It functions by inhibiting bacterial dihydrofolic acid synthesis through competitive inhibition of para-aminobenzoic acid (PABA) binding to dihydropteroate synthase. This compound is valuable for studying sulfonamide mechanisms and understanding bacterial resistance in research applications. -
Anti-bacterial Agent
3,4-Dimethoxytropolone is an anti-bacterial agent with activity against both Gram-positive and Gram-negative bacteria. This compound can be isolated from fermentation broths of Streptoverticillium hadanonense. Its potent antimicrobial properties make it a valuable tool for research applications focused on bacterial resistance and infection mechanisms. -
Anti-Bacterial Agent
20-Deoxysalinomycin is an anti-bacterial agent primarily targeting Gram-positive bacteria. It exhibits significant efficacy against coccidia in poultry, making it a valuable compound for studies on veterinary pharmacology and animal health. Its specific action on these pathogens supports research into effective treatments and prevention strategies in agricultural settings. -
Anti-Bacterial Agent
Cerexin A is an anti-bacterial agent that exhibits strong activity against Gram-positive bacteria. This compound disrupts bacterial cell wall synthesis, leading to cell lysis and death. It holds potential for research applications in developing novel antibacterial therapies and studying mechanisms of resistance in Gram-positive pathogens. -
Antibacterial Metabolite
Renierone is an antibacterial metabolite derived from the marine sponge Reniera sp. It exhibits significant antibacterial activity, making it a valuable tool for research focused on antibiotic development and the exploration of marine-derived compounds. Its unique structure and mechanism of action provide insight into novel therapeutic approaches against bacterial infections. -
Anti-Bacterial Agent
Coriolin C is an anti-bacterial agent known for its activity against Gram-positive bacteria, with limited efficacy against Gram-negative bacteria and yeast, as well as effects on vaginal trichomoniasis. At a concentration of 5 μg/mL, Coriolin C demonstrates a significant inhibitory effect on the growth of Yoshida sarcoma by 61.6%. It is important to note that Coriolin C does not exhibit inhibitory effects on Ehrlich ascites carcinoma in animal models. This compound is valuable for research in microbiology and cancer biology. -
Antibacterial Agent
Leoidin is an inhibitor of the OATP1B1 and OATP1B3 transporters, exhibiting Ki values of 0.08 and 1.84 μM, respectively. This compound effectively blocks sodium fluorescein uptake in CHO cells expressing these transporters. As an antibacterial agent, Leoidin demonstrates activity against both Gram-positive and Gram-negative bacteria by inhibiting phenylalanyl-tRNA synthetase (PheRS) with an IC50 of 42 μM, thereby disrupting bacterial protein synthesis. Leoidin can be isolated from the marine organism L. gangaleoides, making it a valuable tool for microbiological research. -
Antibacterial Agent
Crenatine is an antibacterial agent that primarily targets and disrupts the cell wall synthesis of bacteria. It exhibits greater efficacy against Gram-positive bacteria compared to Gram-negative strains, making it a valuable tool for studies in bacterial infections. Crenatine is ideal for research applications aiming to evaluate antibacterial activity and mechanisms of resistance. -
Anti-Bacterial Agent
Glysperin A is an anti-bacterial agent that targets both Gram-positive and Gram-negative bacteria, including those resistant to aminoglycoside antibiotics. Its broad-spectrum activity makes it a valuable reagent for research applications focused on bacterial resistance mechanisms and the development of new antimicrobial therapies. Glysperin A may facilitate investigations into the efficacy of novel anti-infective strategies and the understanding of bacterial pathogenicity. -
Anti-Bacterial Agent
Monorden E is an anti-bacterial agent that primarily targets cell cycle progression, effectively arresting Jurkat cells in the G1 and G2/M phases. In addition to its cytostatic properties, Monorden E exhibits potent anti-Aspergillus niger activity, making it a valuable tool for research in microbial pathogenesis and cell cycle regulation. -
Antibacterial Activity
Coreoside B, also known as 14-Hydroxycoreoside A, is a naturally occurring flavonoid derived from Coreopsis tinctoria Nutt. It exhibits weak antibacterial activity, making it of interest in microbiological research. Its potential as a lead compound for investigating antibacterial properties can support studies focused on developing new antibacterial agents. -
Anti-Bacterial Agent
Janthinocin A is a potent anti-bacterial agent that targets Gram-positive bacteria, demonstrating strong antimicrobial activity, while also exhibiting moderate efficacy against Gram-negative bacteria. This compound is useful in research aimed at understanding bacterial resistance mechanisms and the development of new antimicrobial therapies. Its unique properties make it a valuable tool for investigating the effects of bacterial infections and potential treatment strategies in the field of microbiology. -
Anti-Bacterial Agent
Saframycin B is an anti-bacterial agent primarily targeting Gram-positive bacteria. It exhibits notable efficacy against various strains, while also demonstrating weak activity against mycobacteria. This compound is useful in research applications aimed at understanding bacterial resistance and developing new antimicrobial strategies. -
Anti-Bacterial Agent
Ekatetrone is an anti-bacterial agent primarily effective against both Gram-positive and Gram-negative bacteria, with notable potency against Mycobacterium tuberculosis. This compound demonstrates significant antibacterial properties, making it a valuable tool for research focused on tuberculosis and other bacterial infections. Its selective activity positions Ekatetrone as a candidate for further investigation in antimicrobial drug development. -
Antibacterial Agent
Antibacterial Agent 310 is a bis-benzimidazole-derived chelating ligand primarily targeting bacterial infections. This compound exhibits significant antibacterial activity and demonstrates the ability to inhibit intracellular viruses. It is suitable for use in antibacterial research and related studies. -
Anti-Bacterial Agent
Pyrronamycin A is an antibacterial agent that exhibits activity against both Gram-positive and Gram-negative bacteria. It has demonstrated efficacy against a range of pathogens, including Staphylococcus aureus, Enterococcus, Escherichia coli, Klebsiella pneumoniae, Proteus, Shigella, and Salmonella. This compound is valuable for research applications focused on antibacterial development and the mechanisms of bacterial resistance. -
Bacterial Inhibitor
VCC234718 is a selective inhibitor of inosine monophosphate dehydrogenase (GuaB2), effectively targeting Mycobacterium tuberculosis (Mtb) to inhibit its growth. With a K value of 100 nM, VCC234718 exhibits non-competitive inhibition involving both IMP and NAD+, demonstrating its ability to disrupt enzymatic function through direct interactions with these metabolites. This compound is valuable for studying mycobacterial infections and developing new treatments for tuberculosis. -
Bacterial Inhibitor
Antitubercular agent-47 (compound 5C) is a potent bacterial inhibitor specifically targeting Mycobacterium tuberculosis. It demonstrates significant efficacy against drug-sensitive (DS), multidrug-resistant (MDR), and extensively drug-resistant (XDR) clinical isolates. This compound is valuable for research applications focused on tuberculosis treatment and drug resistance mechanisms. -
Antibacterial Agent
Austroside A is an antibacterial agent derived from Evodia austrosinensis, targeting bacterial cell functions. It exhibits significant antibacterial activity against antibiotic-resistant strains of Staphylococcus aureus. This compound is particularly valuable for research exploring new therapeutic approaches to combat resistant bacterial infections. -
Anti-Bacterial Agent
Azirinomycin is an anti-bacterial agent that exhibits activity against both Gram-positive and Gram-negative bacteria. Its mechanism of action involves the inhibition of bacterial protein synthesis, making it a valuable tool in the study of bacterial infections and resistance mechanisms. This compound holds potential for the development of novel therapeutic strategies in combating bacterial pathogens. -
Anti-Bacterial Agent
Naphthomycin A is an anti-bacterial agent that primarily targets Gram-positive bacteria and fungi. It functions by inhibiting fatty acid synthesis in coliform bacteria, making it a valuable tool for studying bacterial resistance and metabolic pathways. This compound is suitable for research applications in microbiology and pharmacology, particularly in developing antibiotic compounds. -
Antibacterial Agent
(E)-Nitrofurazone, a topical broad-spectrum antibacterial agent, targets both Gram-negative and Gram-positive bacteria. It also exhibits antiprotozoal and antiparasitic activities. This compound is utilized in research related to superficial wounds, burns, skin infections, pyoderma, infectious skin diseases, as well as conditions such as trypanosomiasis and acute bacillary dysentery. -
Anti-Bacterial Agent
Dihydrodaunomycin is an anti-bacterial agent that exhibits significant antibacterial and antitumor properties. It is effective in research applications aimed at elucidating mechanisms of action against bacterial infections and cancer cell proliferation. Its dual activity makes it a valuable compound for studying the interplay between antibacterial and antitumor effects in various biological contexts. -
ClpP Activator
ACP1b is an activator of the ClpP protease, exhibiting a binding affinity with a Kd of 3.2 μM. This compound demonstrates significant antibacterial activity, effectively inhibiting Neisseria meningitidis and Haemophilus influenzae, with minimum bactericidal concentrations (MBC) of 16 μg/mL and 8 μg/mL, respectively. ACP1b serves as a valuable tool in microbiological research, particularly in studies focused on bacterial protease function and antibiotic resistance mechanisms. -
Bacterial Metabolite
Deoxyenterocin is a bacterial metabolite obtained from Streptomyces, primarily known for its diverse biological activities, including antibiotic, antiviral, and antioxidant effects. It exhibits significant antibacterial activity by inhibiting the growth of pathogens such as S. lutea, S. aureus, K. pneumoniae, and V. percolans at a concentration of 500 μg/mL. Additionally, deoxyenterocin demonstrates antiviral properties, reducing the cytopathic effect of influenza A H1N1 by 60.6% at 50 μg/mL. Moreover, at a concentration of 1 μM, it protects mouse primary cortical neurons from hydrogen peroxide-induced oxidative stress by preserving glutathione levels and mitochondrial membrane potential. -
Anti-Bacterial Agent
Ochracenomicin A is an anti-bacterial agent that exhibits potent activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), as well as Gram-negative bacteria and Candida albicans. This compound is valuable for research applications aimed at investigating bacterial resistance mechanisms and developing new antimicrobial therapies. Its broad-spectrum efficacy makes it a key reagent in studies focused on bacterial infections and potential treatments. -
Anti-Bacterial Agent
Piloquinone is a phenanthrene derivative that exhibits antibacterial activity primarily against mycobacteria and certain protozoa. While its inhibitory effects are not exceptionally potent, it serves as a valuable tool for research applications targeting microbial resistance and the study of antimicrobial mechanisms. This compound may assist in understanding the biochemical pathways involved in bacterial infection and resistance. -
LasB Inhibitor, Antibacterial Activity
Elastase LasB-IN-1 is a selective inhibitor of elastase LasB, exhibiting a potent IC50 value of 76 nM. This compound demonstrates significant antibacterial activity, making it an important tool for research applications focused on bacterial infections. Its specificity for LasB facilitates investigations into the role of elastolytic enzymes in microbial pathogenesis. -
Antibiotic
2-Hydroxyaclacinomycin B is an anthracycline antibiotic known for its ability to inhibit RNA synthesis. Isolated from Streptomyces galilaeus A-862 (FERM BP-45), this compound exhibits significant anti-tumor activity. It serves as a valuable tool in cancer research, enabling studies focused on mechanisms of action and therapeutic potential within oncology. -
Bacterial Inhibitor
Antibacterial agent 149 is a potent laccase inhibitor that exhibits significant antibacterial properties. This compound is particularly effective against bacterial pathogens and has demonstrated high fungicidal activity, making it a valuable tool for studying rice sheath blight and related diseases. Its mechanism of action and specificity enhance its utility in researching bacterial inhibition and plant pathogenic interactions. -
Anti-Bacterial Agent
Bamicetin is an anti-bacterial agent that primarily targets Gram-positive bacteria and Mycobacteria. It exhibits significant activity against various strains, making it a valuable tool for research in microbial resistance and infectious disease studies. Its efficacy in combating these pathogens supports its use in investigations focused on antibiotic development and bacterial virulence mechanisms. -
Antifungal Agent
Ayapin is a phytoalexin primarily derived from sunflower, functioning as a potent antifungal agent. It effectively inhibits the growth of Sclerotinia sclerotiorum, exhibiting an IC50 value of 0.16 mM for 50% inhibition. Ayapin is valuable for research applications focused on the mechanisms of antifungal resistance and strategies to combat sclerotinia infections. -
Anti-Bacterial Agent
4-Diazo-3-methoxy-2,5-cyclohexadien-1-one primarily targets bacterial cells to exert its anti-bacterial activity. It demonstrates effective inhibition against anaerobic bacteria, with a minimum inhibitory concentration (MIC) of 0.4 μg/mL for Clostridium and Bacteroides, and 0.2 μg/mL for Haemophilus. This compound is suitable for research applications focused on developing antibacterial agents and understanding mechanisms of bacterial resistance. -
Antibacterial Agent
2-Acetylthiophene thiosemicarbazone acts as an antibacterial agent, demonstrating significant efficacy against various bacterial strains. Additionally, it exhibits anticancer activity, with an IC50 value of 8.6 μM against HT-29 colon cancer cells. This compound is suitable for research applications focusing on antibacterial and anticancer mechanisms. -
Bacterial Inhibitor
15-Methylhexadeca Sphinganine is an iso-branched sphingolipid that acts as a bacterial inhibitor. It is identified as a component of ceramide-containing phospholipids in bacterial cell membranes. This compound is valuable for research applications focused on understanding bacterial lipid metabolism and exploring potential therapeutic strategies against bacterial infections. -
Anti-Bacterial Agent
Chrysospermin C is an antibacterial agent with demonstrated activity against various Gram-positive bacteria, including Staphylococcus aureus and Bacillus subtilis, as well as the pathogen Klebsiella pneumoniae. Additionally, it exhibits efficacy against individual yeast strains such as Ocher echinoderma and Saccharomyces cerevisiae. This compound is valuable for research applications focusing on antimicrobial resistance and infection control. -
Anti-Bacterial Agent
Cephaibol A is an anti-bacterial agent primarily effective against Gram-positive bacteria. It demonstrates significant activity in targeting infections caused by sensitive Gram-positive strains while showing no efficacy against Gram-negative bacteria. Additionally, Cephaibol A exhibits properties that aid in deworming and combating ectoparasitic infestations. This versatility makes it a valuable tool in research focused on bacterial infections and parasitic diseases. -
Anti-Bacterial Agent
Saquayamycin C1 is an anti-bacterial agent with significant antimicrobial properties. It demonstrates a pronounced inhibitory effect on leukemia P388 cells as well as Adriamycin-resistant P388 cells, making it a valuable compound for cancer research. Its selective activity, particularly against specific cancer cell lines, underscores its potential applications in exploring therapeutic strategies targeting resistant leukemia. However, it shows a weaker effect against Gram-negative bacteria, indicating a selectivity that may be beneficial in tailored antibiotic research. -
Anti-Bacterial Agent
Chloroquinocin is an anti-bacterial agent that exhibits moderate activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). This compound is valuable for research applications aimed at understanding bacterial resistance mechanisms and developing new therapeutic strategies against resistant strains. Its targeted action makes it a significant tool for researchers focusing on infections caused by resilient bacterial pathogens. -
Anti-Bacterial Agent
Papyracon D, an anti-bacterial agent, demonstrates a modest inhibitory effect on L1210 and HL60 cell lines, indicating potential cytotoxicity in certain cancer research applications. Additionally, Papyracon D exhibits weak antibacterial activity against Gram-positive bacteria and some nematodes. Its biological activities may be explored in studies focusing on bacterial resistance and cancer cell modulation. -
Antibacterial Agnet
Carfecillin sodium is an orally active phenyl ester of carbenicillin that functions as an antibacterial agent. It exhibits significant antibacterial activity, making it suitable for research on urinary tract infections and related microbial studies. Its profile allows for exploration in clinical settings focused on antibiotic efficacy and resistance patterns. -
Antibacterial Agent
Celesticetin is an antibacterial agent that targets and inhibits the growth of Sulfolobus acidocaldarius. It demonstrates significant bactericidal activity, making it useful in studying microbial dynamics and mechanisms of antibacterial resistance. Its application extends to various research areas, including microbiology and biochemistry, facilitating the exploration of bacterial cell processes. -
Anti-Bacterial Agent
Griseolutein B is an anti-bacterial agent that exhibits activity against both Gram-positive and Gram-negative bacteria. This compound is useful in studies focused on bacterial infection mechanisms and the development of new antimicrobial therapies. Its broad-spectrum efficacy makes it a valuable tool for researchers investigating bacterial resistance and treatment options. -
Anti-Bacterial Agent
Monorden B is an anti-bacterial agent that disrupts the cell cycle in Jurkat cells, effectively halting progression in both G1 and G2/M phases. This compound demonstrates notable anti-Aspergillus niger activity, making it a valuable tool for research in microbiology and cell cycle regulation. Its unique mechanism of action may provide insights into therapeutic strategies against bacterial infections and fungal pathogens. -
Antibacterial Agent
(E)-2-(4-Cinnamoylphenoxy)acetic acid functions as an antibacterial agent. It exhibits potent antimicrobial activity, demonstrating a minimum inhibitory concentration of 125 μg/mL against various pathogens, including Mycobacterium smegmatis, Staphylococcus aureus, and Candida albicans. This compound is valuable for research applications focused on antimicrobial resistance and the development of new therapeutic agents. -
Anti-Bacterial Agent
Fomecin A is an anti-bacterial agent that exhibits significant activity against Gram-positive bacteria, with weaker effects observed against Gram-negative bacteria and fungi. Its mechanism of action involves disruption of bacterial cell wall synthesis, making it a valuable tool for research focused on combating bacterial infections. Fomecin A can be utilized in studies exploring the efficacy of new antimicrobial compounds and their potential applications in clinical settings. -
Anti-Bacterial Agent
2"-N-Formimidoylsporaricin A is an anti-bacterial agent that exhibits activity against both Gram-positive and Gram-negative bacteria, including strains resistant to aminoglycosides. This compound demonstrates potent antibacterial properties, making it a valuable tool for microbiological research and the development of new therapeutic strategies against resistant bacterial infections. Its broad-spectrum efficacy positions it as a significant candidate for studies focused on antimicrobial resistance and therapeutic intervention. -
Anti-Bacterial Agent
Azicemicin A is an antibacterial agent that exhibits weak antibacterial activity. It has been shown to possess no acute toxicity in mouse models, making it a potential candidate for further research in antibiotic development and safety assessments. Its unique properties may facilitate investigations into the mechanisms of antibiotic action and resistance. -
Anti-Bacterial Agent
Megovalicin B is an anti-bacterial agent that exhibits potent activity against Bacillus subtilis and Escherichia coli. This compound is valuable for research applications aimed at understanding bacterial resistance mechanisms and developing novel antibacterial therapies. Its efficacy in inhibiting pathogenic microbial growth makes it an important tool in microbiology and pharmaceutical development. -
Anti-Bacterial Agent
Ostreogrycin B3 is an anti-bacterial agent targeting Gram-positive bacteria. This compound exhibits significant inhibitory effects against various strains, making it suitable for studies in microbial resistance and antibacterial efficacy. It is a valuable reagent for research applications focused on developing new therapeutics for bacterial infections.
